Magnetom verio syngo mr b17

MR images were acquired at the Baltic Imaging Center (Center for Diagnostic Radiology and Neuroradiology, University Medicine Greifswald) on a 3-T Siemens verio scanner (SIEMENS MAGNETOM Verio syngo MR B17) using a 32-channel head coil. Resting-state fMRI scans were acquired using an echo-planar-imaging sequence (3 × 3 × 3 mm³ voxel size, repetition time (TR) = 2000 ms, echo time (TE) = 30 ms, flip angle = 90°, 34 slices, descending acquisition, field of view 192 × 192 mm², 176 volumes, TA = 6.00 min). Participants were instructed to keep their eyes closed, to not think of anything in particular, and to try not to fall asleep (whether participants fell asleep or not was assessed per self-report directly after the resting-state scan; no participant reported to have fallen asleep). High-resolution anatomical images were acquired using a three-dimensional T1- weighted magnetization prepared rapid gradient echo imaging (1 mm³ isotropic voxel, TR = 2300 ms, TE = 2.96 ms, inversion time = 900 ms, flip angle = 9°, 256 × 240 × 192 mm³ matrix). Further, a diffusion-weighted spin-echo echo-planar imaging sequence was acquired (1.8 × 1.8 × 2.0 mm³ voxel size, TR = 11100 ms, TE = 107 ms, 70 slices, 64 directions (b = 1000 s/mm²), 1 b0).

All patients underwent MR imaging using a 3T system (Magnetom Verio, Syngo MR B17; Siemens Healthcare, Erlangen, Germany) and a pelvic phased-array coil. All examinations included unenhanced axial, sagittal and coronal turbo spin-echo T2 weighted imaging and axial DWI (b values of 0, 100, 800 and 1400 s/mm² used for calculation of ADC map). The parameters on the multi-b value DWI were: repetition time 4300 msec, echo time 80 msec, acquisition matrix 126 x 81, field of view 245 mm x 213 mm, slice thickness 5 mm, flip angle 90°, number of averages 6. A dedicated b = 1400 s/mm² sequence was obtained using similar parameters but with 16 averages. Dynamic gradient echo sequences were obtained during intravenous injection of 0.1 mmol/kg of body weight of gadoterate meglumine (Dotarem®, Guerbet, Roissy, France) at a rate of 2 mL/s.
The protocol was in line with standard guidelines [8 (link)].

Acquisitions were performed on a 3T Siemens MRI (SIEMENS Magnetom Verio syngo MR B17) using a 32-channel phased array coil. The Nordic Neurolab solution (Bergen, Norway) and EPrime 2.0.8 Professional (PST, Sharpsburg, MD, United States) were used to display the visual task via a rear-facing mirror placed on the head coil. An anatomical sequence (T1 3D MP-RAGE, FOV = 256 mm² × 256 mm², 176 slabs, TR = 1,900 ms, TE = 2.26 ms, TI = 900 ms, flip angle = 9°, voxels size = 1 mm³ × 1 mm³ × 1 mm³) and an axial T2 FLAIR sequence were acquired to detect a potential brain abnormality, in which case the subject was excluded from the analysis. fMRI with a sensitive T2-weighted gradient echoplanar imaging sequence with 36 slices of 3 mm was acquired during the 12-min cognitive task. The acquisition parameters were FOV = 192 mm² × 192 mm², EPI factor 64, voxels size = 3 mm³ × 3 mm³ × 3 mm³, TR = 2,000 ms, TE = 30 ms, and flip angle = 90°.

Magnetic resonance (MR) images were acquired on a 3 Tesla Siemens MAGNETOM Verio (Syngo MR B17) using a 32-channel head coil. T-1 weighted MPRAGE sequence (224 sagital slices, voxel size: 0.8 mm × 0.8 mm × 0.8 mm, TR: 2500 ms, TE: 3.47 ms, TI: 1100 ms, flip angle: 7°) were analyzed using region of interest (ROI) defined voxel-based morphometry with SPM 12 (Welcome Department of Cognitive Neurology, London, United Kingdom) running under Matlab (The Math Works). The data preprocessing involved gray matter segmentation, DARTEL based template creation, spatial normalization to MNI-Space and an 5 mm smoothing with a Gaussian kernel as previously described.

The brain imaging of all patients was performed with a 3 Tesla MRI scanner (Siemens Magnetom Verio Syngo MR B17, Erlangen, Germany) using 12-channel head coil. Axial T1 (repetition time [TR]: 150–160 ms, echo time [TE]: 2 ms, slice thickness: 1 mm; field of view (FOV): 210 mm) weighted image, oriented parallel to the anterior commissure-posterior commissure line were used for measurements.
MRI images were evaluated by the same radiologist blinded to the clinical information of the patients. Temporal muscle thickness and TMA was measured as perpendicular to the largest axis on transverse section. The surface area of temporal muscle (TMA) was calculated in semiquantitative volumetric method as the largest surface area from the section (Figures 1A and 1B). The orbital roof and the Sylvian fissure on T1-weighted images were used as anatomical landmarks. The TMA for both right and left temporal muscles were given in mm². Each patient’s mean TMT and TMA were calculated by measuring the left and right sides independently, adding them up, and dividing by half. If there were any indications of prior intervention on one side that could have affected temporal muscle thickness or area (such as prior craniotomy, muscle edema, or subsequent muscle atrophy), this side was excluded from measurements, and only the temporal muscle of this patient’s other side was used for further analysis.