Dulbecco tablets

All solutions were prepared with deionized water or phosphate-buffered saline (PBS) solutions. Phosphate-buffered saline solutions were prepared using Dulbecco tablets obtained from Oxoid Limited (Basingstoke, UK). (±)-Fluoxetine hydrochloride salt (99%), and (S)-duloxetine hydrochloride salt (99%) were both purchased from TCI Chemicals Ltd. (Oxford, UK). Clomipramine hydrochloride salt (98%), initiator azobisisobutyronitrile (AIBN) and caffeine were purchased from Sigma-Aldrich (Gillingham, UK). Methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA), 2-(hydroxyethyl)methacrylate (HEMA), acrylamide (AA), itaconic acid (IA), acrylonitrile, 2-vinylpyridine (2-VP), toluene, methanol, and dimethylsulfoxide (DMSO) were purchased from Acros (Loughborough, UK). Prior to polymerization, the stabilizers in all monomers and crosslinker monomers were removed by passing the solutions over a column packed with alumina (Sigma-Aldrich). Solutions of HCl and NaOH (0.1 mM) in water were used to adjust the pH values of these solutions.

Ethylene glycol dimethacrylate (EGDMA), methacrylic acid (MAA), dopamine hydrochloride salt (99%), and methanol were purchased from Acros (Loughborough, Leicestershire, UK). Prior to polymerization, the stabilizers in the MAA and EGDMA were removed by passing the solutions over a column packed with alumina. 4,4’-Azobis(4-cyanovaleric acid) and serotonin creatinine sulfate monohydrate (98%) were purchased from Sigma Aldrich (Gillingham, UK). For the heat-transfer measurements, a 1× phosphate buffered saline (PBS) solution was prepared with Dulbecco tablets obtained from Oxoid Limited (Basingstoke, UK).