Image acquisition was performed in accordance with the Society of Cardiovascular Computed Tomography guidelines.
23 (
link) If needed, β-blockers were administered to target a heart rate of 60 beats/min. CT was performed using a 256-section CT scanner (
Brilliance iCT; Philips Healthcare). Noncontrast prospective electrocardiographically triggered CT was performed to evaluate coronary calcium score on a per–coronary artery basis.
Subsequently, 0.4 mg of nitroglycerine was sublingually administered to all patients. Patients were given 70 to 80 mL of
contrast agent (Bayer Healthcare Pharmaceuticals), followed by a 50- to 67-mL mixed contrast/saline solution bolus and 30 to 40 mL of intravenous saline solution (injected at a rate of 6-6.7 mL/s). The contrast/saline solution bolus consisted of a 50%/50% mixture for the dialysis cohort and a 30%/70% mixture for the non-CKD group. Coronary CT angiography was performed by using a prospectively electrocardiographically triggered sequential scan (≤60 beats/min) or retrospectively electrocardiographically gated helical scan (>60 beats/min). Depending on body mass, tube voltage ranged between 80 and 120 kV peak, and tube current, between 200 and 300 mA for prospectively triggered scans and 600 mA for retrospectively gated scans. Images were reconstructed with a section thickness of 0.9 mm and an increment of 0.45 mm using a standard kernel.
Jansz T.T., Go M.H., Hartkamp N.S., Stöger J.L., Celeng C., Leiner T., de Jong P.A., Visseren F.J., Verhaar M.C, & van Jaarsveld B.C. (2021). Coronary Artery Calcification as a Marker for Coronary Artery Stenosis: Comparing Kidney Failure to the General Population. Kidney Medicine, 3(3), 386-394.e1.