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Amiodarone hcl

Manufactured by Merck Group
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Sourced in Japan

Amiodarone HCL is a pharmaceutical ingredient used in the production of various medical products. It functions as an antiarrhythmic agent, primarily used in the treatment of certain types of irregular heartbeat conditions. The core function of Amiodarone HCL is to help maintain normal heart rhythm and prevent potentially life-threatening arrhythmias.

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Lab products found in correlation

Sodium iodide, by Merck Group (1 mentions) Diethyl ether et2o, by Thermo Fisher Scientific (1 mentions) Piperidine, by Chem-Impex (1 mentions) 1 2 2 6 6 pentamethylpiperidine, by Merck Group (1 mentions) Ofloxacin, by Merck Group (1 mentions) Fenofibrate, by Fujifilm (1 mentions) Sodium lauryl sulfate, by Merck Group (1 mentions) Rose bengal, by Fujifilm (1 mentions) Benzophenone, by Fujifilm (1 mentions) Hexachlorophene, by Merck Group (1 mentions) Ketoprofen, by Fujifilm (1 mentions) 8 methoxypsoralen, by Merck Group (1 mentions) Chlorpromazine hcl, by Merck Group (1 mentions) Chlorhexidine dihydrochloride, by Merck Group (1 mentions) Promethazine, by Tokyo Chemical Industry (1 mentions) Sulisobenzone, by Merck Group (1 mentions) 6 methylcoumarin, by Merck Group (1 mentions) P aminobenzoic acid, by Merck Group (1 mentions) Norfloxacin, by Fujifilm (1 mentions) 5 methoxypsoralen, by Merck Group (1 mentions)

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Amiodarone (42 citations)

2 protocols using amiodarone hcl

1

Peptide Synthesis Using Fmoc Chemistry

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All solvents and reagents used were purchased from commercial sources and used without further purification. Fmoc-Ala-OH, Fmoc-Pro-OH, Fmoc-Trp (Boc)-OH, Fmoc-His (Trt)-OH, Fmoc-Leu- OH, Fmoc-Ser(tBu)-OH, Fmoc-Gln (Trt)-OH, Fmoc-Tyr (tbu)-OH, Fmoc-Arg (Pbf)-OH, Fmoc- Thr (tBu)-OH and Oxyma-Pure were ordered from Novabiochem (Millipore Sigma Corporation2,2,2-Trifluoroethanol (TFE), Dichloromethane (DCM), Dimethylformamide (DMF), Acetonitrile and Diethyl Ether (Et2O) were ordered from Fisher Scientific (Hampton, NH, United States). Trifluoroacetic acid (TFA), Diisopropylethylamine (DIPEA) and Piperidine were ordered from Chem-Impex International (Wood Dale, IL, United States). Amiodarone HCL, 3-(Tritylthio) propionic acid, Ethanedithiol (EDT), Triisopropylsilane (TIPS), 3-chloropropanethiol, 1,2,2,6,6- PentamethylPiperidine and Sodium Iodide were ordered from Sigma-Aldrich (St. Louis, MO, United States). 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate (TBTU) and 1- Hydroxybenzotriazole hydrate (HOBt) were ordered from P3 Biosystems (Louisville, KY, United States)., St. Louis, MO). Rink amide MBHA resin was ordered from vivitide, LLC (Garder, MA, United States).
Yurko R., Islam K., Weber B., Salama G, & Zahid M. (2023). Conjugation of amiodarone to a novel cardiomyocyte cell penetrating peptide for potential targeted delivery to the heart. Frontiers in Chemistry, 11, 1220573.
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2

Evaluation of Phototoxic Chemicals

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Twenty phototoxic chemicals and 10 non-phototoxic chemicals were evaluated, including 6 drugs, 8 antimicrobials, 6 fragrances, 6 UV absorbers, and 4 other chemicals. Amiodarone HCl (1), anthracene (7), chlorpromazine HCl (9), 5-methoxypsoralen (15), 8-methox-ypsoralen (16), 6-methylcoumarin (17), ofloxacin (18) , hexachlorophene (21), ethylhexyl dimethyl p-aminobenzoate (23), chlorhexidine dihydrochloride (24), sodium lauryl sulfate (27), p-aminobenzoic acid (28), sulisobenzone (29), and lactic acid (30) were purchased from Sigma-Aldrich Japan (Tokyo, Japan). Rose bengal (2), bithionol (4), 3,3'4,5 tetrachlorosalicylanilide (5), fenofibrate (6), benzophenone (11), ketoprofen (13), methyl n-methylantranilate ( 14), and norfloxacin (19) were purchased from Wako Pure Chemical Industries (Osaka, Japan). 3,4',5-Tribromosalicylanilide (3), musk ambrette (8), promethazine (10), musk xylene (12), protoporphyrin IX, disodium (20), 2-octyl salicylate ( 22), 2-octyl methacrylate (25), and penicillin G (26) were purchased from Tokyo Chemical Industry (Tokyo, Japan).
Toyoda A., Sugiyama M., Furihata S., Nishizumi K., Omori T, & Itagaki H. (2017). Development of a modified 3T3 Neutral Red Uptake Phototoxicity Test protocol for evaluation of poorly water-soluble substances. The Journal of toxicological sciences, 42(5).
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