Antibodies against phospho iκbα

Manufactured by Cell Signaling Technology

Sourced in United States

Antibodies against phospho-IκBα are laboratory reagents that specifically recognize the phosphorylated form of the IκBα protein. IκBα is an inhibitor of the NF-κB transcription factor and its phosphorylation is a key regulatory step in the activation of NF-κB signaling.

Automatically generated - may contain errors

Lab products found in correlation

Capric acid, by Merck Group (1 mentions) Phospho jnk, by Cell Signaling Technology (1 mentions) Phospho erk, by Cell Signaling Technology (1 mentions) Phospho p38, by Cell Signaling Technology (1 mentions) Anti p65 antibody, by Santa Cruz Biotechnology (1 mentions) Anti nfatc1 antibody, by BD (1 mentions) Anti bim antibody, by BD (1 mentions) Phospho c jun, by Cell Signaling Technology (1 mentions) M csf, by R&D Systems (1 mentions) Rankl, by R&D Systems (1 mentions) β actin, by Cell Signaling Technology (1 mentions) Lipopolysaccharide lps, by Merck Group (1 mentions)

2 protocols using antibodies against phospho iκbα

Osteoclastogenesis Signaling Pathways

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Capric acid was purchased from Sigma (USA). RANKL and MCSF were obtained from R&D Systems (USA). Antibodies against phospho-IκBα, phospho-JNK, phospho-p38, phospho-ERK, IκBα, JNK, p38, ERK, phospho-c-Jun, and nucleophosmin were purchased from Cell Signaling Technology (USA). Anti-Bim antibody was obtained from BD Biosciences (USA). Anti-p65 antibody was obtained from Santa Cruz Biotechnology (USA). Anti-NFATc1 antibody was purchased from BD Pharmingen (USA).

Kim H.J., Yoon H.J., Kim S.Y, & Yoon Y.R. (2014). A Medium-Chain Fatty Acid, Capric Acid, Inhibits RANKL-Induced Osteoclast Differentiation via the Suppression of NF-κB Signaling and Blocks Cytoskeletal Organization and Survival in Mature Osteoclasts. Molecules and Cells, 37(8), 598-604.

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LPS and MTT Assay with Protein Analysis

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Lipopolysaccharide (LPS) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Antibodies against phospho-IκB-α, IκB-α, phosphoextracellular signal-regulated kinase1/2 (p-ERK1/2), ERK1/2, phospho-p38 (p-p38), p38, p65 and β-actin were purchased from Cell Signaling technology (Bervely, MA, USA).

Park G.H., Park Y., Hong S.S., & Park G.H. (2020). Anti-inflammatory effects of 18-nor-ent-pimara-9(11),15-diene-4β-ol isolated from the roots of Aralia continentalis on LPS-induced in RAW264.7 cells. Applied Biological Chemistry, 63(1).

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