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B6.129s6 nlrp3 1bhk j

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The B6.129S6-Nlrp3™1Bhk/J is a mouse strain that carries a targeted mutation in the Nlrp3 gene, which is involved in the activation of the NLRP3 inflammasome. This strain is commonly used in research related to the NLRP3 inflammasome and its role in various biological processes.

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Lab products found in correlation

C3heb fej, by Jackson ImmunoResearch (2 mentions) B6.129p2 nos2 1lau j, by Jackson ImmunoResearch (2 mentions) B6.129s2 alox15 1fun j, by Jackson ImmunoResearch (2 mentions) C57bl 6, by Jackson ImmunoResearch (2 mentions)

Spelling variants of this product

Nlrp3−/−, (33 citations) B6.Nlrp3−/−, (2 citations)

2 protocols using b6.129s6 nlrp3 1bhk j

1

Genetically Modified Mouse Strains

Check if the same lab product or an alternative is used in the 5 most similar protocols
C57BL/6 (stock no. 000664), Nos2-/- (B6.129P2-Nos2™1Lau/J, stock no. 002609), Alox15-/- (B6.129S2-Alox15™1Fun/J, stock no. 002778) and Alox5-/- (B6.129S2-Alox5™1Fun/J, stock no. 004155), C3HeB/FeJ (stock no. 00658), B6.SJL-Ptprca Pepcb/BoyJ carrying the pan leukocyte marker CD45.1 or Ly-5.1 (stock no. 002014), Ltb4r1-/- (B6.129S4-Ltb4r1™1Adl/J, stock no. 008102), Il1r1-/- (B6.129S7-Il1r1™1Imx/J, stock no. 003245and Nlrp3-/- (B6.129S6-Nlrp3™1Bhk/J, stock no. 021302) were purchased from the Jackson Laboratory. Mice were housed under specific pathogen-free conditions, and in accordance with the University of Massachusetts (UMASS) Medical School, IACUC guidelines. All mouse strains used in this study were of C57BL/6 background unless otherwise indicated.
Mishra B.B., Lovewell R.R., Olive A.J., Zhang G., Wang W., Eugenin E., Smith C.M., Yao J.P., Long J.E., Dubuke M.L., Palace S.G., Goguen J.D., Baker R.E., Nambi S., Mishra R., Booty M.G., Baer C.E., Shaffer S.A., Dartois V., McCormick B., Chen X, & Sassetti C.M. (2017). Nitric oxide prevents a pathogen permissive granulocytic inflammation during tuberculosis. Nature microbiology, 2, 17072.
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2

Genetically Modified Mouse Strains

Check if the same lab product or an alternative is used in the 5 most similar protocols
C57BL/6 (stock no. 000664), Nos2-/- (B6.129P2-Nos2™1Lau/J, stock no. 002609), Alox15-/- (B6.129S2-Alox15™1Fun/J, stock no. 002778) and Alox5-/- (B6.129S2-Alox5™1Fun/J, stock no. 004155), C3HeB/FeJ (stock no. 00658), B6.SJL-Ptprca Pepcb/BoyJ carrying the pan leukocyte marker CD45.1 or Ly-5.1 (stock no. 002014), Ltb4r1-/- (B6.129S4-Ltb4r1™1Adl/J, stock no. 008102), Il1r1-/- (B6.129S7-Il1r1™1Imx/J, stock no. 003245and Nlrp3-/- (B6.129S6-Nlrp3™1Bhk/J, stock no. 021302) were purchased from the Jackson Laboratory. Mice were housed under specific pathogen-free conditions, and in accordance with the University of Massachusetts (UMASS) Medical School, IACUC guidelines. All mouse strains used in this study were of C57BL/6 background unless otherwise indicated.
Mishra B.B., Lovewell R.R., Olive A.J., Zhang G., Wang W., Eugenin E., Smith C.M., Yao J.P., Long J.E., Dubuke M.L., Palace S.G., Goguen J.D., Baker R.E., Nambi S., Mishra R., Booty M.G., Baer C.E., Shaffer S.A., Dartois V., McCormick B., Chen X, & Sassetti C.M. (2017). Nitric oxide prevents a pathogen permissive granulocytic inflammation during tuberculosis. Nature microbiology, 2, 17072.
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