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Magnesium stearate st mg

Manufactured by Merck Group
Sourced in United States

Magnesium stearate (St-Mg) is a fine, white, powder-like substance. It is a common excipient used in the pharmaceutical and nutraceutical industries. Magnesium stearate functions as a lubricant, helping to prevent ingredients from sticking to manufacturing equipment during the production process.

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5 protocols using magnesium stearate st mg

1

Puerarin-Based Dry Powder Inhalation

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Puerarin (analytical grade, Fig 1), CAS Number 3681-99-0 was procured from Sigma Aldrich (P5555). Lactose monohydrate (Inhalation grade; Inhalac 120) was offered by Meggle GmbH (Wasserburg, Germany). Leucine, magnesium stearate (Mg-St) and hard gelatin capsules (size 3) were purchased from Sigma-Aldrich (Australia).
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2

Micronized Ciprofloxacin Dry Powder Formulation

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Micronized ciprofloxacin hydrochloride (µCIP), a fluoroquinolone-type antibiotic, (D50: 5.09 µm) was kindly supplied by Teva Pharmaceutical Works Ltd. (Debrecen, Hungary). Lactose monohydrate, Inhalac ® 70 (IH 70) (D50: 215.00 µm) (MEGGLE Group, Wasserburg, Germany) was used as a carrier base. Magnesium stearate (MgSt) was applied as a surface modifier (Sigma-Aldrich, Budapest, Hungary) (D50: 6.92 µm). Sodium stearate (NaSt) (Alfa Aesar, Heysham, United Kingdom) was used for habit modification.
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3

Amlodipine Besylate Tablet Formulation

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Amlodipine besylate was supplied by Daewon Pharmaceutical Co., Ltd. (Seoul, Korea). Silicified microcrystalline cellulose (Prosolv SMCC® 90) and croscarmellose sodium (CCM-Na) were purchased from JRS PHARMA GmbH & Co. KG (Rosenberg, Germany). Polyvinylpyrrolidone (PVP K25) was purchased from BASF AG (Ludwigshafen, Germany). Magnesium stearate (St-Mg) was purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). All other reagents were of analytical or HPLC grade and were used as received.
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4

Formulation Development of Amlodipine Besylate

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Amlodipine besylate was obtained from Daewon Pharmaceutical Co., Ltd. (Seoul, Korea). MCC was purchased from the following manufacturers: DFE Pharma (Pharmacel®, Dusseldorf, Germany), FMC BioPolymer (Avicel®, Philadelphia, PA, USA), Blanver (MICROCEL® MC, Farmoquímica, Sao Paulo, Brazil), and JRS Pharma GmbH & Co. KG (PROSOLV®SMCC (Silicified microcrystalline cellulose), VIVAPUR®, Heweten®, Rosenberg, Germany). Polyvinylpyrrolidone (PVP) was purchased from BASF AG (Kolidon®, Ludwigshafen, Germany). Croscarmellose sodium (CCS) was purchased from FMC BioPolymer (Ac-Di-Sol®, Philadelphia, PA, USA). Magnesium stearate (St-Mg) was purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). All other reagents were of analytical or high-performance liquid chromatography (HPLC) grade.
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5

Formulation and Characterization of Metformin and Dapagliflozin Tablets

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Metformin HCl and dapagliflozin l-proline were supplied by Kyung-dong Pharm (Seoul, Korea). Hydroxypropyl methylcellulose (Metolose® 90 SH 100,000 SR) and low-substituted hydroxypropyl cellulose (L-HPC) were purchased from Shin-Etsu Chemical Co., Ltd. (Tokyo, Japan). Lactose monohydrate, magnesium stearate (St–Mg), and silicon dioxide were purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). Microcrystalline cellulose (MCC 101) was purchased from DFE Pharma (Goch, Nordrhein-Westfalen, Germany). Calcium silicate was purchased from Fluka (Buchs, St. Gallen, Switzerland). All other reagents used were of analytical or HPLC grade.
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