MRI scans were acquired on either a GE Healthcare System 1.5T or 3.0T platform (GE Discovery MR750, GE Optima MR450w, GE Signa EXCITE, GE Signa HDxt, and GE Signa HDxt; GE Healthcare, Waukesha, WI) using a phase-array coil. The minimum sequence required was high spatial resolution axial oblique T2-weighted image (WI) through the tumor. Diffusion weighted imaging (DWI) and dynamic contrast-enhanced (DCE) were used when available. The oblique axial T2WI sequence was obtained perpendicular to the long axis of the rectal tumor. MR imaging parameters at our institution are summarized in Table 1 . Rectal MRI scans were included if fulfilled the minimum standards agreed upon by the investigators. The minimum standards were the presence of high spatial resolution axial oblique T2WI through the tumor with a slice thickness of 3 mm and an FOV of 180 mm.
Ge optima mr450w
Manufactured by GE Healthcare
Sourced in United States
The GE Optima MR450w is a magnetic resonance imaging (MRI) system designed for high-performance imaging. It offers a powerful superconducting magnet and advanced imaging capabilities to deliver detailed images for diagnostic purposes. The system is engineered to provide efficient workflow and operational performance.
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Lab products found in correlation
Ge signa excite, by GE Healthcare (1 mentions)
Ge discovery mr750, by GE Healthcare (1 mentions)
Ge signa hdxt, by GE Healthcare (1 mentions)
Achieva dstream, by Philips (1 mentions)
Intera, by Philips (1 mentions)
Brilliance 64, by Philips (1 mentions)
Fortrans, by Ipsen (1 mentions)
Cvi42, by Circle Cardiovascular Imaging (1 mentions)
6 protocols using ge optima mr450w
1
Rectal MRI Imaging Protocol
2
MRI-Based Volumetric Analysis of Ventricles
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MRI images were acquired before operation with the resolution of 1mm3/voxel. The MRI used at Sahlgrenska University hospital was either a 1.5 T Intera (Philips Medical Systems, Best, The Netherlands) or a 1.5 T Achieva dStream (Philips Medical Systems, Best, The Netherlands) whereas the MRI used at Östersund Regional Hospital was either a 1.5 T GE Optima MR450w (GE Healthcare, Wausheka, WI, USA) or a 1.5 T GE Signa Voyager (GE Healthcare, Wausheka, WI, USA). The images were exported using DICOM format. The lateral and third ventricle volumes were semi-automatically segmented using the ITK-SNAP software [34 (link)], a method used in a recent study of volumetric change after shunt surgery [42 (link)] and exemplified in fig. 1 .
3
Cross-Modality Imaging Protocol for Abdominal Diagnosis
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Diagnostic CT scans were performed on a 64-detector row CT system (Brilliance 64, Philips Medical Systems, Cleveland, OH) using 0.5 s of gantry rotation time. The routine protocol for abdominal scan uses tube current modulation (TCM) at 120 kVp with 5 mm slice thickness. The reference parameter of the TCM system is the dose right index (DRI), which is set as 15 in our routine practice. The acquired data were reconstructed by iDose iterative reconstruction algorithm with standard reconstruction kernel (B). The voxel size of the reconstructed CT image was 0.68 mm in the axial plane and 5 mm in the longitudinal direction.
Diagnostic MRI scans were performed on a 1.5 T system (GE Optima MR450w, GE Medical Systems Inc., Waukesha, WI, USA), which has a flat indexed tabletop to which a constructed receiver coil frame can be attached without patient body contact. The T1-weighted in-phase and out-phase MR image sets were obtained with a 2D fast RF-spoiled dual gradient echo sequence. Echo time was 4.4/2.2 ms, whereas repetition time and flip angle were 110 ms and 80°, respectively. The bandwidth for the entire FOV (34 cm × 34 cm) was 62.5 kHz. The frequency encoding direction was anterior–posterior. Acquired data were reconstructed axially using a 512 × 512 matrix. The voxel size of the reconstructed MRI image was 0.66 mm in the axial plane and 8 mm in the longitudinal direction.
Diagnostic MRI scans were performed on a 1.5 T system (GE Optima MR450w, GE Medical Systems Inc., Waukesha, WI, USA), which has a flat indexed tabletop to which a constructed receiver coil frame can be attached without patient body contact. The T1-weighted in-phase and out-phase MR image sets were obtained with a 2D fast RF-spoiled dual gradient echo sequence. Echo time was 4.4/2.2 ms, whereas repetition time and flip angle were 110 ms and 80°, respectively. The bandwidth for the entire FOV (34 cm × 34 cm) was 62.5 kHz. The frequency encoding direction was anterior–posterior. Acquired data were reconstructed axially using a 512 × 512 matrix. The voxel size of the reconstructed MRI image was 0.66 mm in the axial plane and 8 mm in the longitudinal direction.
4
T1 Mapping for Cardiac Fibrosis Assessment
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CMR with the same 1.5T scanner (GE Optima MR450w, GE Healthcare, Milwaukee, WI) and 32-channel cardiac coil was performed on all the patients. Mid-ventricular short axis images were obtained. T1 was measured i.e., T1 mapping was performed with a ECG-triggered Look-Locker sequence (TR 4440 s, TE 2.016 ms, 30 TI's between 95 and 1279 ms, in-plane resolution 1.48 mm, slice thickness 8 mm). The images were acquired during breath holds. MRI images were analyzed off-line using an in-house MATLAB application (Matlab, MathWorks Inc, Natick, MA). Regions of interest were segmented manually. The segments with visible LGE i.e., replacement fibrosis were excluded from the analysis. The possible position differences between images with different TI's were taken into account by segmenting each image separately and calculating ROI-wise T1 using the mean intensities of each image. T1 relaxation time was measured 10–15 min after contrast agent injection (0.4 mL/kg but not more than 30 mL of Dotarem (500 mM, Guerbet AG, Zürich, Switzerland).
5
MRI Examination with Intestinal Distension
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On the day of MRI, patients had to have been fasting for at least four h before the examination. An oral ingestion of 500 mL to 1000 mL of PEG (Fortrans®, Ipsen Pharma, Paris, France) was used to achieve an adequate intestinal distension.The MRI imaging examinations with no bowel cleansing the day before the examination and with no colonic distension (no enema) were performed as previously described[20 (link),21 (link),23 (link),24 (link)] with a 1.5 Tesla GE Optima MR 450w (General Electric HealthCare, Fairfield, CT) in Clermont-Ferrand, France, and with a 1.5 Tesla Avanto MRC1 (Siemens, Erlangen, Germany) in Reims, France.
6
Cardiac Imaging Evaluation Protocol
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Accuracy of the echocardiographic methods was defined by agreement according to CMR15 (link)–17 (link). CMR images were obtained using a 1.5 Tesla system (GE Optima MR450W, GE Healthcare, Waukesha, WI) with a phased-array cardiac coil. Cine images were acquired during breath-hold using a steady-state free precession cine sequence with retrospective gating18 (link). Slice thickness 8 mm, no gaps, field of view 300–360 mm, 25 phases/cycle. Analysis was performed using CVI42 (Circle Cardiovascular Imaging Inc., Version 5.6.5, Canada). End-diastole was defined as for echocardiography. Endocardium and epicardium were manually delineated in the short-axis-stack, papillary muscles were considered part of the LV volume. The subjects were classified in four groups according to age, gender and indexed values19 (link) of the EDVENDO and LVM20 (link); normal, dilatation, hypertrophy, dilatation and hypertrophy.
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