The results are presented as mean ± SD. GraphPad InStat (USA) and SPSS 17.0 (SPSS, USA) software were used to conduct all statistical analyses. Means were compared using the unpaired t-test and statistical significance was considered to be shown by P values of < 0.05.
Instat
Manufactured by IBM
Sourced in United States
InStat is a high-precision laboratory equipment designed for scientific research and analysis. It is capable of performing a wide range of measurements and data collection tasks with a high degree of accuracy and reliability. The core function of InStat is to provide researchers and scientists with a versatile and powerful tool for their experimental and analytical needs.
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Lab products found in correlation
2 protocols using instat
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Statistical Analysis of Research Data
2
Randomized Trial of Novel Therapy
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Data analysis was carried out using the Graph Pad Instat and SPSS version 14 software package. Forward stepwise multiple logistic regression analysis was used for assessment of the primary end-point. Other categorical data were compared between the treatment groups by Pearson’s Chi-squared test or Fisher’s exact test, as appropriate. The unpaired t test was used for continuous variables and the Mann–Whitney test for ordinal data like the APACHE II score.
Sample size calculation was performed assuming a 28-day all-cause mortality of 30 % in the control group and 10 % in the study group. A sample size of 59 completed patients in each group was required to attain a power of 80 % at a significance level of 5 %. The primary efficacy end-point of 28-day all-cause mortality was assessed in the modified intention-to-treat population which was defined a priori. This primary analysis population included all randomized patients who had received at least six doses of the study medication. Safety was assessed in the safety population, defined as all subjects who received even a single dose of the study medication. Mortality difference in the intention-to-treat population that included all randomized subjects was analyzed as a secondary end-point.
Sample size calculation was performed assuming a 28-day all-cause mortality of 30 % in the control group and 10 % in the study group. A sample size of 59 completed patients in each group was required to attain a power of 80 % at a significance level of 5 %. The primary efficacy end-point of 28-day all-cause mortality was assessed in the modified intention-to-treat population which was defined a priori. This primary analysis population included all randomized patients who had received at least six doses of the study medication. Safety was assessed in the safety population, defined as all subjects who received even a single dose of the study medication. Mortality difference in the intention-to-treat population that included all randomized subjects was analyzed as a secondary end-point.
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