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Connectome

Manufactured by Siemens
Sourced in Germany

Connectome is a high-performance lab equipment designed for advanced neuroimaging applications. It utilizes the latest imaging technologies to capture detailed, high-resolution images of the brain's neural connections and structure. The core function of Connectome is to provide researchers and scientists with a powerful tool for mapping and analyzing the complex networks within the human brain.

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4 protocols using connectome

1

Accuracy of Huygens' Surface Approximation

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We compared the B-field, E-field, and the PNS oracle values generated through Equation 3 (Huygens’ surface representation) with that from the computationally intensive direct calculation to test how well the fast Huygens’ based solution approximates the expensive full model (EM simulation plus PNS oracle extraction). We assessed the accuracy of the approach for the female and male model in seven Siemens gradient coils (Siemens Healthineers, Erlangen, Germany): four whole-body gradients (Sonata, Quantum, Prisma, and Connectome) and three head-only gradients (AC84, AC88, and the more recent “Impulse” head gradient54 ). We compared the estimates B˜C , E˜C , and P˜C with their directly computed counterparts BC, EC, and PC (computed using full EM simulations from the coil windings) as follows:
χB=maxBCB˜CBCχE=maxECE˜CECχP=maxPCP˜CPC.
Note that we only assessed this metric in regions where the amplitude of the quantity is above 1% of its global maximum, as the metric is ill-posed in low-amplitude regions. We assessed the error as a function of the number of basis functions on the Huygens’ surface by randomly removing basis functions and reporting the resulting error. Truncation of the full Huygens’ basis sets was done randomly, and we report χ for the average of 200 such choices.
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2

Accuracy of Huygens' Surface Approximation

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We compared the B-field, E-field, and the PNS oracle values generated through Equation 3 (Huygens’ surface representation) with that from the computationally intensive direct calculation to test how well the fast Huygens’ based solution approximates the expensive full model (EM simulation plus PNS oracle extraction). We assessed the accuracy of the approach for the female and male model in seven Siemens gradient coils (Siemens Healthineers, Erlangen, Germany): four whole-body gradients (Sonata, Quantum, Prisma, and Connectome) and three head-only gradients (AC84, AC88, and the more recent “Impulse” head gradient54 ). We compared the estimates B˜C , E˜C , and P˜C with their directly computed counterparts BC, EC, and PC (computed using full EM simulations from the coil windings) as follows:
χB=maxBCB˜CBCχE=maxECE˜CECχP=maxPCP˜CPC.
Note that we only assessed this metric in regions where the amplitude of the quantity is above 1% of its global maximum, as the metric is ill-posed in low-amplitude regions. We assessed the error as a function of the number of basis functions on the Huygens’ surface by randomly removing basis functions and reporting the resulting error. Truncation of the full Huygens’ basis sets was done randomly, and we report χ for the average of 200 such choices.
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3

Language Comprehension and Arithmetic Processing fMRI

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Language fMRI data were collected using a 3T scanner (Siemens Connectome) with an echo-planar imaging (EPI) sequence (32-channel head coil, repetition time [TR] = 720 ms, echo time [TE] = 33.1 ms, in-plane field-of-view [FOV] = 208 × 180 mm, 72 slices, 2.0-mm isotropic voxels, and multiband acceleration factor of 8). The language task (block design) consisted of math and story trials. The math trials (auditory presentation) included addition and subtraction problems (e.g., “Fourteen plus twelve”), and participants responded to a two-alternative forced-choice by pressing a button (e.g., “twenty-nine or twenty-six”). The difficulty of the question increased after three consecutive correct answers and decreased after one failure. The same difficulty adjustment was employed in the story trials. In story trials passages adapted from Aesop’s fables were presented (5–9 sentences), after which participants responded to a two-alternative forced-choice for comprehension (e.g., after a story about an eagle that saves a man who had done him a favor, participants were asked, “Was that about revenge or reciprocity?”)
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4

Cardiac MRI Imaging of Artificial Heart

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Retrospective steady-state gradient recall echo (GRE) cinematographic
(CINE) MRI [repetition time (TR) = 5.1, echo time (TE) = 1.4, flip angle =
12°, 1 mm by 1 mm by 6 mm, 24 frames per heartbeat] was performed on a 3T
clinical scanner (Connectome, Siemens Healthineers, Erlangen, Germany) and
synced to the 40 bpm pneumatic actuator pumps. CINE GRE MRI was performed over
five actuator cycles to reconstruct a high-resolution 2D section and repeated to
cover the entire heart. 3D high-resolution structural GRE MRI (TR = 5.1, TE =
1.4, flip angle = 12°, 1 mm isotropic resolution) was performed to
identify actuators, silicone myocardium, and ventricular chamber.
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