Scanning was carried out at the Montreal Neurological Institute on a 1.5 T Siemens whole body MRI system. Structural T1 volumes were acquired for each participant using a three-dimensional (3D) gradient echo pulse sequence with sagittal volume excitation (repetition time = 22 ms, echo time = 9.2 ms, flip angle = 30°, 180 1 mm contiguous sagittal slices). The rectangular field-of-view for the images was 256 mm (SI)×204 mm (AP). Patient groups did not differ as to when sessions took place past entry (weeks; PNS mean = 15.9, s.d. = 5.8; non-PNS mean = 19.9, s.d. = 7.8; t = 1.82, df = 60, p = 0.07).
Whole body mri system
Manufactured by Siemens
The Whole-body MRI system is a medical imaging device designed to capture detailed images of the entire human body. It utilizes powerful magnetic fields and radio waves to generate high-resolution images, allowing medical professionals to diagnose and monitor a wide range of health conditions.
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5 protocols using whole body mri system
1
Structural MRI of Patient Groups
2
Structural and Functional Brain Imaging
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MRI scanning was performed on a 1.5-Tesla Siemens whole-body MRI system at Xuan Wu Hospital in Beijing. Gradient echo-planar imaging was used to acquire 20 axial slices (6 mm thickness, 1.8 mm gap, field of view, 220 × 220 mm2; matrix size, 64 × 64; repeat time, 2000 ms; echo time, 50 ms; flip angle, 90°; 132 repetitions per time series). A high-resolution T1-weighted 3D MRI sequence with the following parameters was used: 1.9 mm thickness; 0.95 mm gap; repeat time, 1970 ms; echo time, 3.93 ms; and flip angle, 15°.
3
Resting-state fMRI Acquisition Protocol
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Functional Magnetic Resonance Imaging data were collected using a 3-T Siemens whole-body MRI system at the Tiantan Hospital. Subjects were asked to keep heads still, eyes closed, and stay awake during scans. Resting-state functional scans were acquired with a T2*-weighted echo-planar imaging sequence, with specific scanning parameters: echo time, 30 ms; repetition time, 2,480 ms; flip angle, 90°, 36 axial slices in each volume; field of view, 256 mm × 256 mm; matrix size, 64 × 64; slice thickness, 3 mm, and voxel size = 3 mm × 3 mm × 4 mm. A total of 240 volumes were collected (9 min and 55 s in total) for each subject.
4
Resting-State fMRI Dataset for Functional Connectivity
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The normative rs-fcMRI dataset consisted of 104 healthy participants (41 males, mean age 21.4 ± 2.8 years) who were part of a publicly available dataset (Buckner ; Thomas Yeo et al., 2011 (link)). The study was conducted with the written consent of each subject and approved by the Partners’ Institutional Review Board. Imaging was performed on a 3 T Siemens whole-body MRI System with a phased-array head coil. Each subject completed two 6.2-min (124 frames) resting-state functional magnetic resonance imaging (fMRI) scans (TR = 3000 ms, TE = 30 ms, FA = 85°, 3 × 3 × 3 mm voxels, FOV = 216, 47 axial slices with interleaved acquisition and no gap). Participants were asked to rest in the scanner with their eyes open. rs-fcMRI data were processed in accordance with the strategy of Fox et al. (Fox et al., 2005 (link)) as implemented by Van Dijk et al. (Van Dijk et al., 2010 (link)). Structural data, including a high-resolution, multi-echo, T1-weighted, magnetization-prepared, gradient-echo image (TR = 2200 ms, TI = 1100 ms, TE = 1.54 ms for image 1 to 7.01 ms for image 4, FA = 7°, 1.2 × 1.2 × 1.2 mm voxels, FOV = 230), were also downloaded from the same dataset as rs-fc MRI.
5
3D T1-weighted MRI Acquisition
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T1-weighted MRI images were acquired at the Montreal Neurological Institute on a 1.5T Siemens whole-body MRI system using a 3D gradient-echo pulse sequence (TR = 22ms; TE = 9.2ms; flip angle = 30º; FOV = 256mm SI x 204mm AP; 180 sagittal slices; voxel size = 1mm 3 ).The same scanner and identical parameters were used for all subjects and timepoints.
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