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Anti tβrii

Manufactured by Santa Cruz Biotechnology
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Anti-TβRII is a laboratory reagent that recognizes and binds to the Transforming Growth Factor-Beta Receptor II (TβRII) protein. TβRII is a cell surface receptor that plays a crucial role in the TGF-beta signaling pathway, which regulates various cellular processes. The anti-TβRII reagent can be used for the detection and analysis of TβRII expression in cellular and biological samples.

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Lab products found in correlation

Polyvinylidene fluoride membrane, by Merck Group (1 mentions) Enhanced chemiluminescence, by Cytiva (1 mentions) Anti β actin, by Santa Cruz Biotechnology (1 mentions) Anti c myc, by Cell Signaling Technology (1 mentions) Anti p21cip1, by Santa Cruz Biotechnology (1 mentions) Anti smad4, by Santa Cruz Biotechnology (1 mentions) Anti ki67, by Vector Laboratories (1 mentions) Anti c myc, by Santa Cruz Biotechnology (1 mentions) Anti phospho smad2, by Cell Signaling Technology (1 mentions) Anti phospho smad3, by Cell Signaling Technology (1 mentions) Anti smad2, by Cell Signaling Technology (1 mentions) Anti smad3, by Cell Signaling Technology (1 mentions) Tgf β1, by R&D Systems (1 mentions)

Spelling variants of this product

TβRII (16 citations) Anti-TβRII (clone L21) and PAI-1 (2 citations) Anti-TβRII monoclonal primary antibody (clone C-4) (2 citations)

2 protocols using anti tβrii

1

Western Blot Protein Analysis

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Total cell lysates were harvested and boiled in sample buffer. Equal amounts of protein lysate were resolved by SDS-PAGE and transferred onto polyvinylidene fluoride membranes (Millipore). The following primary antibodies were used in our analysis: anti-TβRII, anti-β-actin (Santa Cruz Biotechnology, Inc.), anti-p21CIP/WAF1, and anti-c-Myc (Cell Signaling Technology). Proteins were visualized by enhanced chemiluminescence (Amersham Biosciences).
Wu Y., Su M., Zhang S., Cheng Y., Liao X.Y., Lin B.Y, & Chen Y.Z. (2016). Abnormal expression of TGF-beta type II receptor isoforms contributes to acute myeloid leukemia. Oncotarget, 8(6), 10037-10049.
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2

Transforming Growth Factor-β1 Regulation

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TGF-β1 was purchased from R&D Systems (Minneapolis, MN). Human has-miR-20a mimics and control miRNA mimics were from Thermo Scientific Dharmacon (Lafayette, CO). Antibodies were purchased as follows: anti-Smad2, anti-Smad3, anti-phospho-Smad2 and anti-phospho-Smad3 from Cell Signaling (Denver, MA); anti-p21CIP1, anti-Smad4, anti-c-Myc and anti-TβRII from Santa Cruz Biotechnology (Santa Cruz, CA); anti-Ki67 from VECTOR (Burlingame, CA); and anti-β-actin from Sigma Biochemicals (St Louis, MO). The TRKI (LY2109761) was kindly provided by Dr. Jonathan Yingling (Eli Lilly Pharmaceuticals, Indianapolis, IN).
Yang S., Cho Y.J., Jin L., Yuan G., Datta A., Buckhaults P, & Datta P.K. (2015). An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC. Oncotarget, 6(32), 33237-33252.
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