All the patients underwent non-enhanced chest CT examinations for detecting COVID-19 pneumonia in the supine position during end-inspiration. The CT scans of non-pregnant adults were performed with a 64-section multi-detector CT scanner (uCT780, United imaging, Shanghai, China, or Optima 660, GE Medical System, Milwaukee, WI, USA). The CT scans of pregnant women and children were all performed with the same 64-section multi-detector CT scanner (Optima 660, GE Medical System, Milwaukee, WI, USA). The protocols were as follows. For non-pregnant adults: tube voltage 120 kV, automatic tube current (120–380) mA, thickness (5–7) mm, slice interval 5 mm, rotation speed 0·5 s, and helical pitch 1·0875:1 or 1·375:1. For pregnant women: tube voltage 120 kV, automatic tube current (10–300) mA, thickness (7–10) mm, slice interval 5 mm, rotation speed 0·6 s, helical pitch 1·375:1, and noise index 15. Thyroid, abdomen, and plevis were protected by the lead sheath. The dose-length product (DLP) was 50–150 mGy·cm. For children: tube voltage 100 kV, automatic tube current (30-100) mA, thickness (3–5) mm, slice interval 1 mm, rotation speed 0·6 s, and helical pitch 0·969:1. Lung window images at 0·625 to 1 mm thickness were reconstructed. Iterative reconstruction technique was implemented. The informed consents for CT examination were obtained from all patients.
Optima 660
Manufactured by GE Healthcare
Sourced in United States, China, Germany
The Optima 660 is a compact centrifuge designed for general laboratory applications. It features a fixed-angle rotor with a maximum speed of 6,000 rpm and a maximum RCF of 4,500 x g. The Optima 660 has a capacity of 6 x 50 mL tubes.
Automatically generated - may contain errors
Lab products found in correlation
Somatom definition as, by Siemens (9 mentions)
Uct 780, by United Imaging (8 mentions)
Discovery hd 750, by GE Healthcare (5 mentions)
Lightspeed vct, by GE Healthcare (5 mentions)
Iomeron 400, by Bracco (4 mentions)
Somatom sensation 16, by GE Healthcare (3 mentions)
Optima ct540, by GE Healthcare (3 mentions)
Lightspeed pro 16, by GE Healthcare (2 mentions)
Omnipaque, by GE Healthcare (2 mentions)
Lightspeed xtra, by GE Healthcare (2 mentions)
Discovery ct750 hd, by GE Healthcare (2 mentions)
Somatom sensation 16, by Siemens (2 mentions)
Ict sp 128 slice, by Philips (2 mentions)
Somatom drive, by Siemens (1 mentions)
Ge optima ct660, by GE Healthcare (1 mentions)
Bright speed 16, by GE Healthcare (1 mentions)
Lightspeed 16, by GE Healthcare (1 mentions)
Lightspeed vct 64, by GE Healthcare (1 mentions)
Uct 760, by United Imaging (1 mentions)
Somatom definition scanner, by Siemens (1 mentions)
57 protocols using optima 660
1
CT Imaging of COVID-19 Pneumonia
2
Liver MDCT Imaging Protocol
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Non contrast-enhanced phase and triple-phase contrast-enhanced MDCT was performed with a 64-detector row scanner (Optima 660, GE Healthcare, USA). MDCT scanning parameters were 120 kVp, 100–470 mAs (NI 16.36), 2.5-mm slice thickness and table speed 0.984/1mm/rotation. Scans were carried out including a region encompassing the liver from diaphragm to iliac crests. Phases were as follows; hepatic arterial phase 30–40 s after injection of 120 mL of a nonionic contrast medium (Iomeprol, Iomeron 400, Bracco, Milan, Italy) with a bolus-triggered technique (120 kVp; 40–60 mA), portal and equilibrium phase 90 s and 120 s after contrast injection. The contrast medium was administered at a rate of 4 mL/s through antecubital vein with an automated injector system (Empower CTA, E-Z-EM Inc., New York, USA).
3
Standardized CT Acquisition Protocol
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CT scans were obtained using a 64-detector row (Brilliance; Philips Healthcare, Cleveland, OH, USA), 128-detector row (Optima 660; GE Healthcare, Waukesha, WI, USA), or 256-detector row (iCT; Philips Healthcare) CT scanner. Scans were obtained from the lung apices to the lung bases. The CT acquisition parameters were as follows: 120–140 kVp; 100–200 mA; reconstruction interval, 1–2.5 mm; and section thickness, 1.3–2.5 mm and 1–2.5 mm for axial and coronal images, respectively. All CT data were reconstructed using a high spatial frequency algorithm.
4
CT Angiography for Coronary Artery Bypass Graft Evaluation
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CT angiography (OPTIMA 660, GE, 64 slices) was performed to assess grafts patency and lumen uniformity 6–12 after CABG (Fig. 2 ). Oral nitroglycerin was given prior to the scan in order to achieve coronary vasodilatation; β-blocker (Esmololo, 1 fl) was also administered to patients with heart rate above 65 bpm. After defining the region of interest, 95 ml of an iodine based contrast agent (Ultravist 370) was injected at a flow rate of 5 ml/sec followed by a saline chaser bolus of 40 mL at 5 ml/sec, via a 20 gauge needle in the antecubital fossa. The gantry rotation time was 0.35 s, peak tube voltage was 120kVp, and current (mA) was adjusted per patient’s body weight. SVG were graded by an independent observer (radiologist) to be (1) patent with < 50% stenosis (2) patent with > 50% stenosis (3) occluded. In addition, as shown in Fig. 3 , SVG were classified to have uniform lumen or lumen irregularities defined as lumen diameter variation > 0.5 mm.
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– CT angiography of externally stented SVG to the right coronary artery in a 2D (
5
Comprehensive CT Imaging of COVID-19 Patients
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All images were obtained with one of three CT systems (uCT 780, United Imaging, Shanghai, China; Optima 660, GE Healthcare, Milwaukee, WI, USA; SOMATOM Definition AS+, Siemens Healthineers, Erlangen, Germany); patients were scanned in the supine position. The main scanning parameters were as follows: tube voltage, 120 kVp; automatic tube current modulation (ATCM), 30–70 mA s; pitch, 0.99–1.22 mm; matrix, 512 ×512; field of view, 350 mm × 350 mm. All images were reconstructed with a slice thickness of 0.625–1.250 mm with the same increment. We analyzed peak CT images (CT image of the largest lesion range on multiple CT examinations during hospitalization) as well as CT images at discharge and during follow-up after discharge. Since physicians did not have a deep understanding of COVID-19 at the beginning of the epidemic and since the condition of patients in the acute phase changed rapidly, most patients received multiple CT scans during their hospitalization, with an average of 4.64±2.02.
6
CTPA Imaging Protocol for COVID-19 Assessment
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Computed tomography pulmonary angiogram (CTPA) was performed within 48 h of ICU admission using a 64-slice multidetector CT machine (General Electric Optima 660 or General Electric Discovery HD). All patients were non-intubated and examined in a supine position. A breath-hold was requested from the patients trying to avoid respiratory motion artifact. Bolus IV injection of non-ionic contrast medium was using an injector pump followed by 40 ml of saline solution. Rotation time was 0.33 s, 0.62 mm thickness, 0.7 reconstruction increment (mm), and 1 pitch. The images were transferred to the workstation (General Electric®, Milwaukee, WI, USA, AW 4.7), where the axial slides and multi-planar reformation were reviewed retrospectively by an experienced cardiothoracic radiologist (JV) blinded to clinical data. The following items were reported specifically for the study: (1) chest CT-SS for COVID-19 infection, (2) RV and LV diameters, (3) aorta diameter, and (4) pulmonary artery (PA) diameter (Figure 1 ).
7
Paranasal Sinus CT Imaging for Nasal Secretions
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Children with sticky purulent secretion in the nasal cavity or with a headache as the chief complaint underwent a paranasal sinus computed tomography (CT) scan (Optima 660; GE, Norwalk, CT, USA).
8
CTA Neck Imaging Protocol
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CTA neck studies were performed on one of our institution's CT scanners, including the Optima 660, Lightspeed Xtra, Lightspeed Pro‐16 or Discovery HD‐750 (GE Healthcare; Milwaukee, WI). CTA studies were acquired in helical scanning mode with coverage extending from the aortic arch to the C1 ring. Studies were collimated at 0.625 mm, with kVp of 120, auto‐mA, and with a rotation time of 0.5 s. For each study, ≈90 mL of nonionic iodinated contrast (iohexol, Omnipaque, GE Healthcare) was administered at a rate of 4 to 5 mL/s using a power injector and SmartPrep region‐of‐interest on the aortic arch via an 18‐gauge peripheral intravenous catheter.
9
CT Imaging Protocol for Respiratory Disease
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CT scan data were available for 980 patients representing a total of 506,341 2D images (517 slices per patient on average). Summary statistics for the clinical, biological, and CT scan data are provided in Table 1 . Three different models of CT scanners were used: two General Electric CT scanners (Discovery CT750 HD and Optima 660 GE Medical Systems, Milwaukee, USA) and a Siemens CT scanner (Somatom Drive; Siemens Medical Solutions, Forchheim, Germany). All patients were scanned in a supine position during breath-holding at full inspiration. The acquisition and reconstruction parameters were of 120 kV tube voltage with automatic tube current modulation (100–350 mAs), 1 mm slice thickness without interslice gap, using filtered-back-projection (FBP) reconstruction (Somatom Drive) or blended FBP/iterative reconstruction (Discovery or Optima). Axial images with slice thickness of 1 mm were used for coronal and sagittal reconstructions.
10
Non-Enhanced Chest CT Scans for Pregnant and Non-Pregnant Women
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All patients underwent non-enhanced chest CT scans in the supine position during end-inspiration, using one of the 64-section multi-detector CT scanners (uCT780, United imaging, Shanghai, China, or Optima 660, GE Medical System, Milwaukee, WI, USA). The CT scan covered from thoracic entrance to the level of posterior costophrenic angle. The parameters were as follows: tube voltage 120 kV, automatic tube current (100–380) mA, thickness (5–10) mm, slice interval 5 mm, rotation speed 0.5 s or 0.6 s, and helical pitch 1.0875:1 or 1.375:1. The noise index (NI) and dose-length product (DLP) were 15 and 50–150 mGy·cm for pregnant women, while 7.99 and 250–400 mGy·cm for non-pregnant women. Thyroid, abdomen, and pelvis were protected by lead sheath during CT examinations. Lung window images at 0.625 to 1 mm thickness were reconstructed. Iterative reconstruction technique was implemented. The informed consents for CT examination were obtained from all patients.
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