Participants were scanned on a Siemens 3T Connectome Skyra with a 100 mT gradient coil and a 32-channel Siemens receive head coil (Glasser et al., 2013 (link)). B0 field maps, B1- and B1 + maps were collected to correct for readout distortion and intensity inhomogeneities. T1-weighted (T1w) images were collected as a 3D single-echo magnetization prepared – rapid gradient echo (MP-RAGE) images with the following acquisition parameters: voxel size = 0.7 mm isotropic, FOV = 224 mm, matrix = 320, 256 sagittal slices per slab, TR = 2400 ms, TE = 2.14 ms, TI = 1000 ms, FA = 8°, Bandwidth = 210 Hz per pixel, echo spacing = 7.6 ms, GRAPPA factor = 2, 10% phase encoding over-sampling (A-P), dwell time = 7.4 μs. T2-weighted (T2w) images were collected as 2 variable flip angle turbo spin-echo sequences averaged together with the following acquisition parameters: voxel size = 0.7 mm isotropic, FOV = 224 mm, matrix = 320, 256 sagittal slices per slab, TR = 3200 ms, TE = 565 ms, BW = 744 Hz/pixel, no fat suppression pulse, GRAPPA = 2, turbo factor = 314, echo train length = 1105 echoes, 10% phase encoding oversampling, dwell time = 2.1 μs.
3t connectome skyra
Manufactured by Siemens
Sourced in Germany
The 3T Connectome Skyra is a powerful magnetic resonance imaging (MRI) system designed by Siemens. It operates at a field strength of 3 Tesla, providing high-resolution imaging capabilities. The core function of the 3T Connectome Skyra is to generate detailed images of the human brain and its neural connections.
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5 protocols using 3t connectome skyra
1
High-Resolution MRI Brain Imaging Protocol
2
High-Resolution Diffusion-Weighted MRI Acquisition
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MRI acquisitions were carried out using a custom‐made Siemens 3T “Connectome Skyra” (Siemens, Erlangen, Germany), provided with a Siemens SC72 gradient coil and stronger gradient power supply with maximum gradient amplitude (Gmax) of 100 mT/m (initially 70 and 84 mT/m in the pilot phase), which allows improvement of diffusion‐weighted imaging (DWI).
High‐resolution T1‐weighted MPRAGE images were collected using the subsequent parameters: voxel size = 0.7 mm, TE = 2.14 ms, TR = 2400 ms (Van Essen et al.,2012 ). DWIs were acquired using a single‐shot 2D spin‐echo multiband Echo Planar Imaging sequence and equally distributed over three shells(b‐values 1,000; 2,000; 3,000 mm/s2), 90 directions per shell, spatial isotropic resolution of 1.25 mm (Sotiropoulos et al., 2013 ). More details about experimental setup and preprocessing pipelines are described elsewhere (Glasser et al., 2013 ; Glasser et al., 2016 ; Sotiropoulos et al., 2013 ; van Essen et al., 2012 ).
High‐resolution T1‐weighted MPRAGE images were collected using the subsequent parameters: voxel size = 0.7 mm, TE = 2.14 ms, TR = 2400 ms (Van Essen et al.,
3
Structural MRI of Connectome Skyra
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All participants were scanned on a customized Siemens 3T “Connectome Skyra” at Washington University using a standard 32-channel Siemens receive and a body transmission coil (van Essen). The distortion corrected T1 weighted images [3D MPRAGE TR = 2400 ms, TE = 2.14 ms, TI = 1000 ms, FA = 8°, Bandwidth (BW) = 210 Hz per pixel, Echo Spacing (ES) = 7.6 ms, 0.8 mm isotropic resolution] and T2 weighted images (SPACE, TR = 3200 ms, TE = 565 ms, 0.8mm isotropic resolution with same matrix and slices as T1 weighted images) were used for this project.
4
Multimodal MRI Acquisition Protocols
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2.2.1 DTD and HC2 databases. Participants were scanned using a 3T GE Discovery 750 MRI with an eight-channel head coil. Twenty-two individuals (DTD=9, HC2=13) were scanned in 2011 and 2013, and anatomical images were acquired using a T1-weighted SPGR sequence (Minimum Full TE, 11° flip angle, 1 mm isotropic voxels, 25.6 cm FOV). Sixteen additional individuals (DTD=11, HC2=5) were scanned in the same scanner in 2017, with anatomical images acquired using a T1-weighted fast SPGR sequence (Minimum Full TE, 10° flip angle, 1 mm isotropic voxels, 25.6 cm FOV, ARC factor 2). 2.2.2 HC1 database. All HC participants were scanned on a customized Siemens 3T "Connectome Skyra" housed at Washington University in St. Louis, using a standard 32-channel Siemens head coil and a body transmission coil designed by Siemens using the gradients of the WU-Minn and MGH-UCLA Connectome scanners. T1-weighted 3D MPRAGE were acquired with TR=2400 ms, TE=2.14 ms, TI=1000 ms, 8° flip angle, FOV=224x224, 0.7 mm isotropic voxel, bandwidth=210 Hz/px, iPAT=2, and acquisition time=7:40 (min:sec).
5
Structural MRI Acquisition and Preprocessing
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Anatomical data were sourced from the publicly available dataset of the Human Connectome Project (HCP) 1200 Subjects Data Release under the HCP Open Access Data Use terms ( https://www. humanconnectome.org/study/hcp-young-adult/document/1200subjects-data-release ; Van Essen et al., 2013 ) (link). The following description of data acquisition and preprocessing steps from the HCP project follow reporting guidelines from Horien et al. (2021) on the use of secondary neuroimaging datasets.
HCP data were acquired using a custom Siemens 3T Connectome Skyra scanner with a 32 channel receiver head coil and custom body transmission coil. Data were acquired over four separate scanning sessions; each session was approximately one hour in length. The structural data were acquired during one of those sessions. Two T1 weighted anatomical images were acquired using a 3D magnetization-prepared rapid gradient-echo (MP-RAGE) sequence with GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) (R = 2) [TR = 2400ms; TE = 2.14ms; TI = 1000ms; slices = 256; voxel volume = 0.7mm 3 ; slice thickness = 0.7mm; distance factor = 50%; slice oversampling = 0.0%; FOV = 224 × 224mm; matrix = 320 × 320; flip angle = 8°; phase encoding direction = A → P; interleaved acquisition; echo spacing = 7.6ms].
HCP data were acquired using a custom Siemens 3T Connectome Skyra scanner with a 32 channel receiver head coil and custom body transmission coil. Data were acquired over four separate scanning sessions; each session was approximately one hour in length. The structural data were acquired during one of those sessions. Two T1 weighted anatomical images were acquired using a 3D magnetization-prepared rapid gradient-echo (MP-RAGE) sequence with GeneRalized Autocalibrating Partially Parallel Acquisitions (GRAPPA) (R = 2) [TR = 2400ms; TE = 2.14ms; TI = 1000ms; slices = 256; voxel volume = 0.7mm 3 ; slice thickness = 0.7mm; distance factor = 50%; slice oversampling = 0.0%; FOV = 224 × 224mm; matrix = 320 × 320; flip angle = 8°; phase encoding direction = A → P; interleaved acquisition; echo spacing = 7.6ms].
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