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Anti phospho chk2 thr68 clone c13c1

Manufactured by Merck Group
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The Anti-phospho-Chk2 (Thr68) (clone C13C1) is a laboratory research tool used to detect and analyze the phosphorylation of the Chk2 protein at the threonine 68 (Thr68) residue. It is a monoclonal antibody that can be used in various immunoassay techniques, such as Western blotting, to study the activation and regulation of the Chk2 protein, which plays a crucial role in the cellular DNA damage response pathway.

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Lab products found in correlation

Anti geminin clone e5q9s, by Thermo Fisher Scientific (2 mentions) Anti phospho atm ser1981 clone 10h11, by Thermo Fisher Scientific (2 mentions) Anti atm clone d2e2, by Thermo Fisher Scientific (2 mentions) Polyclonal anti phospho atr ser428, by Merck Group (2 mentions) Polyclonal anti phospho atr thr1989, by Merck Group (2 mentions) Anti atr clone e1s3s, by Merck Group (2 mentions) Anti phospho chk1 ser317 clone d12h3, by Merck Group (2 mentions) Anti mdm2 clone smp14, by Merck Group (2 mentions) Anti p53 clone 1c12, by BD (2 mentions) Anti p21 clone sxm30 ruo, by BD (2 mentions) Anti γh2ax, by Merck Group (2 mentions) Anti caspase 2 clone 11b4, by Merck Group (2 mentions) Anti actin c4 from, by MP Biomedicals (2 mentions)

2 protocols using anti phospho chk2 thr68 clone c13c1

1

Immunoblotting Antibodies for DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Unless otherwise indicated antibodies were purchased from Cell Signaling Technology (Danvers, MA). The following antibodies were used: anti-caspase-2 (clone 11B4 from Millipore); anti-Geminin (Clone E5Q9S); anti-CDT1 (Clone D10F11); anti-phospho-ATM (Ser1981) (clone 10H11 from Invitrogen and clone 10H11.E12); anti-ATM (clone D2E2); polyclonal anti-phospho-ATR (Ser428); polyclonal anti-phospho-ATR (Thr1989); anti-ATR (clone E1S3S); anti-phospho-Chk1 (Ser317) (clone D12H3); anti-Chk1 (clone 2G1D5); anti-phospho-Chk2 (Thr68) (clone C13C1); anti-Chk2 (polyclonal); anti-MDM2 (clone SMP14, Sigma-Aldrich); anti-p53 (clone 1C12); anti-p21 (clone SXM30(RUO), BD Biosciences); anti-actin (C4 from MP Biomedicals); and anti-γ-H2AX (EMD Millipore). All cell culture media reagents were purchased from Thermo Fisher (Carlsbad, CA, USA). Unless otherwise indicated, all other reagents were purchased from Sigma-Aldrich (St. Louis, MO, USA).
Boice A.G., Lopez K.E., Pandita R.K., Parsons M.J., Charendoff C.I., Charaka V., Carisey A.F., Pandita T.K, & Bouchier-Hayes L. (2021). Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis. Oncogene, 41(2), 204-219.
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2

Immunoblotting Antibodies for DNA Damage Response

Check if the same lab product or an alternative is used in the 5 most similar protocols
Unless otherwise indicated antibodies were purchased from Cell Signaling Technology (Danvers, MA). The following antibodies were used: anti-caspase-2 (clone 11B4 from Millipore); anti-Geminin (Clone E5Q9S); anti-CDT1 (Clone D10F11); anti-phospho-ATM (Ser1981) (clone 10H11 from Invitrogen and clone 10H11.E12); anti-ATM (clone D2E2); polyclonal anti-phospho-ATR (Ser428); polyclonal anti-phospho-ATR (Thr1989); anti-ATR (clone E1S3S); anti-phospho-Chk1 (Ser317) (clone D12H3); anti-Chk1 (clone 2G1D5); anti-phospho-Chk2 (Thr68) (clone C13C1); anti-Chk2 (polyclonal); anti-MDM2 (clone SMP14, Sigma-Aldrich); anti-p53 (clone 1C12); anti-p21 (clone SXM30(RUO), BD Biosciences); anti-actin (C4 from MP Biomedicals); and anti-γ-H2AX (EMD Millipore). All cell culture media reagents were purchased from Thermo Fisher (Carlsbad, CA, USA). Unless otherwise indicated, all other reagents were purchased from Sigma-Aldrich (St. Louis, MO, USA).
Boice A.G., Lopez K.E., Pandita R.K., Parsons M.J., Charendoff C.I., Charaka V., Carisey A.F., Pandita T.K, & Bouchier-Hayes L. (2021). Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis. Oncogene, 41(2), 204-219.
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