Alum 77161

Manufactured by Thermo Fisher Scientific

Sourced in United States

Alum (77161) is a chemical compound commonly used in various laboratory applications. It serves as a coagulant and flocculant, assisting in the precipitation and removal of suspended particles from liquid solutions. The product is available in powder form.

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Lab products found in correlation

M csf 216 mc, by R&D Systems (1 mentions) Nigericin n7143, by Merck Group (1 mentions) Flagellin from salmonella typhimurium tlrl stfla, by InvivoGen (1 mentions)

2 protocols using alum 77161

Inflammatory Stimuli Reagents Protocol

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LPS (L3024), ATP (A7699) and nigericin (N7143) were purchased from Sigma-Aldrich (St. Louis, MO, USA). MSU (tlr-msu) was purchased from Invivogen (San Diego, CA, USA). Alum (77161) was purchased from Thermo-Scientific (Thermo Fisher Scientific, MA, USA). M-CSF (216-MC) was purchased from R&D Systems (Lille, France). Recombinant HSP70 was kindly provided by Carmen Garrido’s team.

Martine P., Chevriaux A., Derangère V., Apetoh L., Garrido C., Ghiringhelli F, & Rébé C. (2019). HSP70 is a negative regulator of NLRP3 inflammasome activation. Cell Death & Disease, 10(4), 256.

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Immune Modulators and Signaling Inhibitors

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Nigericin sodium salt (catalog no. N7143), BFA (B7651), ATP (A2383), and LPS from E. coli 055:B5 (L2880) were purchased from Sigma-Aldrich. CRT 0066101 (4975), kb ND 142–70 (3962), 2-APB (1124), BAPTA-AM (2787), U73122 (1268), CID 755673 (3327), Gö 6976 (2253), and Gö 6983 (2285) were purchased from Tocris Bioscience. Nano-SiO₂ (tlrl-sio) and flagellin from Salmonella typhimurium (tlrl-stfla) were obtained from InvivoGen. Alum (77161) was purchased from Thermo Fisher Scientific.

Zhang Z., Meszaros G., He W.T., Xu Y., de Fatima Magliarelli H., Mailly L., Mihlan M., Liu Y., Puig Gámez M., Goginashvili A., Pasquier A., Bielska O., Neven B., Quartier P., Aebersold R., Baumert T.F., Georgel P., Han J, & Ricci R. (2017). Protein kinase D at the Golgi controls NLRP3 inflammasome activation. The Journal of Experimental Medicine, 214(9), 2671-2693.

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