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Strain code 236 cb17scid

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Strain Code 236-CB17SCID is a laboratory mouse model commonly used in research. It is a severe combined immunodeficiency (SCID) strain that lacks functional T and B cells, making it useful for studies involving xenografts and other applications requiring an immunodeficient host.

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Lab products found in correlation

Anti gfp antibody, by Rockland Immunochemicals (2 mentions)

2 protocols using strain code 236 cb17scid

1

Teratoma Formation from Embryonic Stem Cells

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Teratoma generation was described previously (Zhang et al., 2016b (link)). Briefly, 4-weeks old female severe combined immunodeficiency (SCID) mice (Charles River Laboratory Strain Code 236-CB17SCID) were subcutaneously injected with ESCs for teratoma formation. Approximately 9 weeks after injection, tumors were dissected and fixed in 4% paraformaldehyde. Tissues were then Paraffin-embedded and subjected for either Hematoxylin and Eosin (H&E) staining or immunohistochemistry using anti-GFP antibody (Rockland, 600–406-215) using standard procedures at University of Michigan ULAM in vivo animal core.
Zhang H., Khoa L.T., Mao F., Xu H., Zhou B., Han Y., O’Leary M., Nusrat A., Wang L., Saunders T.L, & Dou Y. (2019). MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State. Cell reports, 29(9), 2659-2671.e6.
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2

Teratoma Formation from Embryonic Stem Cells

Check if the same lab product or an alternative is used in the 5 most similar protocols
Teratoma generation was described previously (Zhang et al., 2016b (link)). Briefly, 4-weeks old female severe combined immunodeficiency (SCID) mice (Charles River Laboratory Strain Code 236-CB17SCID) were subcutaneously injected with ESCs for teratoma formation. Approximately 9 weeks after injection, tumors were dissected and fixed in 4% paraformaldehyde. Tissues were then Paraffin-embedded and subjected for either Hematoxylin and Eosin (H&E) staining or immunohistochemistry using anti-GFP antibody (Rockland, 600–406-215) using standard procedures at University of Michigan ULAM in vivo animal core.
Zhang H., Khoa L.T., Mao F., Xu H., Zhou B., Han Y., O’Leary M., Nusrat A., Wang L., Saunders T.L, & Dou Y. (2019). MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State. Cell reports, 29(9), 2659-2671.e6.
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