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Sorbitan monooleate 80 span 80

Manufactured by Daejung Chemicals
Sourced in Cameroon

Sorbitan monooleate 80 (Span 80) is a non-ionic surfactant. It is a viscous liquid with an HLB value of 4.3. Span 80 is primarily used as an emulsifier and stabilizer in various applications.

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2 protocols using sorbitan monooleate 80 span 80

1

Formulation and Characterization of Bezafibrate Delivery Systems

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Bezafibrate was from Cayman Chemical Co. (Pittsfield Charter Township, MI, USA). Hydroxypropyl methylcellulose (HPMC), hydroxypropyl cellulose (HPC) and polyvinyl alcohol (PVA) were bought from Shin-Etsu Co. (Tokyo, Japan). Carboxymethylcellulose sodium (Na-CMC) and gelatin were purchased from Duksan Chemical Co. (Ansan, South Korea). Dextran, docusate sodium and hyaluronic acid were from Sigma-Aldrich (St. Louis, MO, USA), respectively. Polyvinylpyrrolidone (PVP K30), solutol HS15, poloxamer 188, poloxamer 407 and cremophor ELP were procured from BASF (Ludwigshafen, Germany). Polyethylene glycol 6000 and polyethylene glycol 1540 were acquired from Duksan Chemical Co. (Ansan, South Korea). Sodium lauryl sulphate (SLS), polysorbate 20 (Tween 20), polysorbate 80 (Tween 80), sorbitan monolaurate 20 (Span 20) and sorbitan monooleate 80 (Span 80) were obtained from Daejung Chemical Co. (Siheung, South Korea). Polysorbate 60 (Tween 60) (Croda, Singapore) was purchased from Masung and Co. (South Korea). All other solvents and chemical substances were of reagent grade.
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2

Fenofibrate Formulation Optimization

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Fenofibrate was supplied by Hanmi Pharm. Co. (Suwon, South Korea). Hydroxypropyl methylcellulose, hydroxypropyl cellulose, and polyvinyl alcohol were procured from Shin-Etsu Co. (Tokyo, Japan). Carboxymethylcellulose sodium and dextran were obtained from Duksan Chemical Co. (Ansan, South Korea) and Sigma-Aldrich (St Louis, MO, USA), respectively. PVP K30, Solutol HS15, poloxamer 407, cremophore A25, cremophore RH40, cremophore EL, and cremophore ELP were purchased from BASF (Ludwigshafen, Germany). Polyethylene glycol (400 and 6000) was acquired from Duksan Chemical Co. Gelatin, polysorbate 80 (Tween 80), and sorbitan monooleate 80 (Span 80) were supplied by Daejung Chemical Co. (Siheung, South Korea). Fenofibric acid, HP-β-CD, SLS, and docusate sodium were obtained from Hanmi Pharm. Co. Clofibric acid was purchased from Sigma-Aldrich. All other solvents and chemical substances were of reagent grade.
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