The morphologies of bare 316L SS, PTMC and PTMC-E5 samples were observed by scanning electron microscopy (SEM, JSM-7001F, Japan Electron Optics Laboratory Co., Ltd., Tokyo, Japan), and the surface chemical composition of PTMC-E5 was examined using Fourier transform infrared spectrometry (FTIR,
NICOLET 5700, Thermo Electron Corporation, Waltham, MA, USA) with reflectance mode and X-ray photoelectron spectroscopy (XPS, K-Alpha, Thermo Electron Limited, Winsford, UK) [29 (
link),30 (
link),31 (
link)]. The wettability of the bare 316L SS, PTMC and PTMC-E5 sample surfaces was assessed by water and blood contact angle measurement (
DSA 100, Krüss GmbH, Hamburg, Germany) [32 (
link)]: the samples were first dried and then fixed to a glass slide. A droplet of dH
2O was added to the surface to detect contact angle using a horizontal microscope. For each sample, the mean value of the contact angle was calculated from at least three individual measurements taken at different locations on the samples examined. The drug-eluting portion of the estradiol was also investigated, as described elsewhere [16 (
link)].
Yao H., Li J., Li N., Wang K., Li X, & Wang J. (2017). Surface Modification of Cardiovascular Stent Material 316L SS with Estradiol-Loaded Poly (trimethylene carbonate) Film for Better Biocompatibility. Polymers, 9(11), 598.