A 3 T MAGNETOM Verio scanner was used (Siemens Healthcare, Erlangen, Germany). Participants were scanned using T2* weighted multiband echo-planar imaging (EPI) sequence in resting-state. They were requested to have their eyes open and fixated on a white cross displayed on a dark background on the display, using an Avotec projection system. They were asked to not think of anything specific. Scanning parameters were as follows: TR = 600 ms, TE = 30 ms, FA = 55°, multiband factor = 2, voxel size = 3 × 3 × 4 mm3 and 1000 volumes. Brain coverage was restricted to the cerebral cortex, midbrain, pons and subcortical structures (cerebellum excluded). Two separate scans were done for every subject (same day), hence providing 174 sessions of rs-fMRI data for 87 subjects. This mathematically boosted the statistical power of our analysis.
3 t magnetom verio scanner
Manufactured by Siemens
Sourced in Germany
The 3-T MAGNETOM Verio scanner is a high-field magnetic resonance imaging (MRI) system manufactured by Siemens. It operates at a magnetic field strength of 3 Tesla, which provides enhanced image quality and resolution compared to lower field strengths. The 3-T MAGNETOM Verio is designed for a wide range of clinical applications, including neuroimaging, musculoskeletal imaging, and body imaging.
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Lab products found in correlation
9 protocols using 3 t magnetom verio scanner
1
Resting-state fMRI of Healthy Brains
2
Resting-State fMRI of Healthy Brain Function
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Participants arriving at the research lab for their scheduled testing appointment
were re-screened for eligibility, thoroughly screened for MRI contraindications,
and re-consented to ensure full comprehension of the study’s procedures,
benefits and their rights.
Functional magnetic resonance imaging. Participants were scanned
in a 3T MAGNETOM Verio scanner (Siemens Healthcare, Erlangen, Germany) using
T2*-weighted multiband echo planar imaging (EPI) sequence in resting state
(participants were required to keep their eyes open and not think of anything
specific and fixated on a white cross displayed in dark background on the screen
using an Avotec projection system), with TR = 600 ms, TE = 30 ms, voxel
size = 3 × 3 × 5 mm3, FA = 55°, multiband factor = 2, 1000
volumes. Brain coverage was limited to cerebral cortex, subcortex, and midbrain
(cerebellum was excluded).
were re-screened for eligibility, thoroughly screened for MRI contraindications,
and re-consented to ensure full comprehension of the study’s procedures,
benefits and their rights.
Functional magnetic resonance imaging. Participants were scanned
in a 3T MAGNETOM Verio scanner (Siemens Healthcare, Erlangen, Germany) using
T2*-weighted multiband echo planar imaging (EPI) sequence in resting state
(participants were required to keep their eyes open and not think of anything
specific and fixated on a white cross displayed in dark background on the screen
using an Avotec projection system), with TR = 600 ms, TE = 30 ms, voxel
size = 3 × 3 × 5 mm3, FA = 55°, multiband factor = 2, 1000
volumes. Brain coverage was limited to cerebral cortex, subcortex, and midbrain
(cerebellum was excluded).
3
Multimodal Brain MRI Acquisition Protocol
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Patients’ brain MRI were acquired with a 3T MAGNETOM Verio scanner (Siemens,
Germany) or 3T MR750 scanner (GE Healthcare, USA) in Huashan Hospital, Fudan
University. The following sequences were obtained: axial T2-weighted images,
axial T1-weighted images, fluid-attenuated inversion recovery images,
diffusion-weighted images, and contrast-enhanced T1-weighted images.
Germany) or 3T MR750 scanner (GE Healthcare, USA) in Huashan Hospital, Fudan
University. The following sequences were obtained: axial T2-weighted images,
axial T1-weighted images, fluid-attenuated inversion recovery images,
diffusion-weighted images, and contrast-enhanced T1-weighted images.
4
3T MRI Structural Brain Imaging
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Magnetic resonance imaging (MRI) was performed on a 3 T Magnetom Verio scanner (Siemens, Erlangen, Germany, equipped with a 32-channel head array coil and syngo MR B17 software).
5
Multimodal MRI in Dementia Subtypes
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Twenty-four patients with DLB, nine patients with AD and fifteen healthy control subjects underwent cerebral MRI in a 3-T MAGNETOM Verio scanner (Siemens Healthcare, Erlangen, Germany). T1-weighted spin echo sequences were collected using the following parameters: repetition time = 1900 ms, echo time = 2.53 ms, inversion time = 900 ms, field of view = 192 mm and slice thickness = 1 mm. The voxel size was 1 mm × 1 mm × 1 mm.
6
Multi-Echo fMRI Acquisition Protocol
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For MK and G1, multi-echo (ME) fMRI images24 (link) were acquired on a Siemens 3 T MAGNETOM Prisma scanner, with a 20-channel receive-only head coil: TR 1.3 s; multi-TE 15, 34.24, 53.48 ms; flip angle 68°; voxel size 3 × 3 × 3 mm; 48 slices. An anatomical T1-weigthed image was acquired: TR 2.3 s; TE 2.76 ms; flip angle 9°; voxel size 1 × 1 × 1 mm). For G2, single-echo sequences were acquired on a Siemens 3 T MAGNETOM Verio scanner, with a 20-channel receive-only head coil: TR 3 s; TE 25 ms; flip angle 90°; voxel size 2 × 2 × 2.5 mm; 49 slices. An anatomical T1-weigthed image was acquired: TR 2.3 s; TE 4.18 ms; flip angle 9°; voxel size 1 × 1 × 1 mm).
7
3T MRI for Whole-Brain Structural and Functional Imaging
8
Volumetric Brain Imaging Protocol with FreeSurfer
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T1-weighted images were acquired with a 3-T Magnetom Verio Scanner (Siemens Healthcare, Erlangen, Germany) using three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP-RAGE) protocol with the following parameters: inversion time 900 ms; repetition time 2,300 ms; echo time 2.98 ms; flip angle 9°; field of view 256 × 240 × 176 mm; voxel size 1 × 1 × 1 mm. To analyze gray matter volume and cortical thickness, T1-weighted images were preprocessed using FreeSurfer version 5.3.0 (https://surfer.nmr.mgh.harvard.edu/) 19 (link).
MR images were preprocessed using the standard pipeline recon-all. After normalization and skull-stripping of the T1-weighted images, cortical tissue boundaries were reconstructed and transformed to a subject-specific surface mesh. The distance between pial and gray/white matter surfaces at each vertex location of the mesh was calculated in order to obtain cortical thickness measurements20 (link). Based on Desikan-Killiany’s cortical parcellation, regional cortical thickness and gray matter volume was extracted separately for the several brain regions in each hemisphere and averaged for the analysis. All images were visually checked for misplaced tissue boundaries and manually corrected if necessary.
MR images were preprocessed using the standard pipeline recon-all. After normalization and skull-stripping of the T1-weighted images, cortical tissue boundaries were reconstructed and transformed to a subject-specific surface mesh. The distance between pial and gray/white matter surfaces at each vertex location of the mesh was calculated in order to obtain cortical thickness measurements20 (link). Based on Desikan-Killiany’s cortical parcellation, regional cortical thickness and gray matter volume was extracted separately for the several brain regions in each hemisphere and averaged for the analysis. All images were visually checked for misplaced tissue boundaries and manually corrected if necessary.
9
3T MRI for Whole-Brain Structural and Functional Imaging
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Images were acquired using a Siemens 3-T MAGNETOM Verio scanner with a 32-channel head coil at the Texas A&M Institute for Preclinical Studies (TIPS), College Station, TX. High-resolution whole-brain anatomical images were acquired using a T1-weighted magnetization prepared rapid gradient echo (MPRAGE) pulse sequence [150 coronal slices, voxel size = 1 mm isotropic, repetition time (TR) = 7.9 ms, echo time (TE) = 3.65 ms, flip angle = 8°]. Whole-brain functional images were acquired using a multiband T2*-weighted echo planar imaging (EPI) pulse sequence [56 axial slices, multiband factor = 8, TR = 600 ms, TE = 29 ms, flip angle = 52°, image matrix = 96 × 96, field of view = 240 mm, slice thickness = 2.5 mm with no gap]. Each EPI pulse sequence began with dummy pulses to allow the MR signal to reach steady state and concluded with an additional 6 s blank epoch to allow for measurement of the unfolding of the blood oxygenation level dependent (BOLD) response.
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