Lo dose insulin syringe 29 g 1 2 inch

medetomidine (1000 µg/mL, Domitor; Nippon Zenyaku Kogyo Co., Ltd., Fukushima, Japan) at a dose of 200 µg/kg was administered intramuscularly to rats in all groups. Fifteen minutes after medetomidine administration, atipamezole (5000 µg/mL, Antisedan; Nippon Zenyaku Kogyo Co., Ltd., Fukushima, Japan) at doses of 400, 800, or 1600 µg/kg or 0.32 mL/kg saline solution (equal volume to 1600 µg/kg atipamezole) was administered. According to the treatment received, groups were named MA400, MA800, MA1600, and control groups, respectively. The drug solution was injected into the caudal part of the left thigh using a microsyringe (1/2 mL BD Lo-Dose Insulin Syringe 29 G × 1/2 inch; BD, Franklin Lakes, NJ, USA) at 10:00 a.m.

Medetomidine (1000 µg/mL, Domitor; Nippon Zenyaku Kogyo Co., Ltd., Fukushima, Japan) in doses of 50, 100, or 200 µg/kg, or a physiological saline solution (0.2 mL/kg) as the control, were administered intramuscularly to the rats. According to the treatment received, groups were named MED50, MED100, MED200, and control group, respectively. The drug solution was injected into the caudal part of the left thigh using a micro syringe (1/2 mL BD Lo-Dose Insulin Syringe 29 G × 1/2 inch; BD, Franklin Lakes, NJ, USA) at 10:00 a.m.