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Axiom biobank plus genotyping array

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The Axiom Biobank Plus Genotyping Array is a high-throughput genotyping platform designed for large-scale population-based biobank studies. The array features a comprehensive set of markers selected to provide genome-wide coverage and enable robust, cost-effective genotyping of a diverse range of human populations.

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Close spelling variants of this product

Axiom array (59 citations) Axiom Biobank array (36 citations) BioBank Array (9 citations) PLUSTM (3 citations)

2 protocols using axiom biobank plus genotyping array

1

Replication of Psoriatic Arthritis GWAS

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We used an independent cohort of 2234 PsA cases and 5708 controls to replicate our findings. Briefly, people of European Caucasian ancestry were collected in North America and Sweden, and were genotyped using the Affymetrix Axiom Biobank Plus Genotyping Array. More details of this cohort, as well as quality control procedures applied to the genotype data, have been described previously.17
Budu-Aggrey A., Bowes J., Stuart P.E., Zawistowski M., Tsoi L.C., Nair R., Jadon D.R., McHugh N., Korendowych E., Elder J.T., Barton A, & Raychaudhuri S. (2017). A rare coding allele in IFIH1 is protective for psoriatic arthritis. Annals of the Rheumatic Diseases, 76(7), 1321-1324.
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2

Genome-wide genotyping of psoriasis cohort

Cited 1 time
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Psoriasis cases (n = 6344) and unrelated, unaffected controls (n = 6085) of European Caucasian descent were collected in North America and Sweden (Supplementary Material, Table S1). The cohort was genotyped using the Affymetrix Axiom Biobank Plus Genotyping Array at the Affymetrix facility (Santa Clara, CA). In addition to the exome array content analysed in the present study, the chip included genome-wide and customized content analysed as part of a concurrent GWAS meta-analysis (16 (link)).
Dand N., Mucha S., Tsoi L.C., Mahil S.K., Stuart P.E., Arnold A., Baurecht H., Burden A.D., Callis Duffin K., Chandran V., Curtis C.J., Das S., Ellinghaus D., Ellinghaus E., Enerback C., Esko T., Gladman D.D., Griffiths C.E., Gudjonsson J.E., Hoffman P., Homuth G., Hüffmeier U., Krueger G.G., Laudes M., Lee S.H., Lieb W., Lim H.W., Löhr S., Mrowietz U., Müller-Nurayid M., Nöthen M., Peters A., Rahman P., Reis A., Reynolds N.J., Rodriguez E., Schmidt C.O., Spain S.L., Strauch K., Tejasvi T., Voorhees J.J., Warren R.B., Weichenthal M., Weidinger S., Zawistowski M., Nair R.P., Capon F., Smith C.H., Trembath R.C., Abecasis G.R., Elder J.T., Franke A., Simpson M.A, & Barker J.N. (2017). Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling. Human Molecular Genetics, 26(21), 4301-4313.
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