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Sorafenib

Manufactured by Adooq
Sourced in United States

Sorafenib is a lab equipment product. It is a small molecule that inhibits multiple kinases, including Raf kinases, VEGFR, and PDGFR.

Automatically generated - may contain errors

2 protocols using sorafenib

1

Hepatoma Cell Line Culture and Drug Treatments

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Human hepatoma cell lines HepG2 and Huh7 were used as previously described [9 (link),40 (link)]. Cells were maintained in Roswell Park Memorial Institute medium (RPMI1640) (Sigma-Aldrich, St. Louis, MO, USA) supplemented with 10% fetal calf serum (FCS) and 200 U/mL penicillin and 200 μg/mL streptomycin at 37 °C in a 5% CO2 atmosphere. Sorafenib, regorafenib, and lenvatinib were purchased from AdooQ Bioscience (Irvine, CA, USA), Cayman Chemical (Ann Arbor, MI, USA), and ChemScene LLC (Monmouth Junction, NJ, USA), respectively.
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2

Viral Transduction Constructs for FLT3 Signaling

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pMSCV-Ires-GFP, pMSCV-FLT3WT-Ires-GFP, and pMSCV-FLT3ITD-Ires-GFP were described previously.21 (link) Ruxolitinib and pacritinib were purchased from Chemietech Inc. Quizartinib, sorafenib, midostaurin, lestaurtinib, crenolanib, gilteritinib, and momelotinib were purchased from AdooQ Bioscience.
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