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Modular analytics evo

Manufactured by Roche
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Sourced in Germany

The Modular Analytics EVO is a versatile and automated laboratory instrument designed for clinical chemistry and immunoassay analysis. It offers a modular and scalable platform to support a wide range of diagnostic testing needs.

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Lab products found in correlation

Kx 21 hematology analyzer, by Sysmex (1 mentions)

4 protocols using modular analytics evo

1

Comprehensive Blood Analysis Protocol

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Blood analysis was performed by Sysmex KX‐21 hematology analyzer. Serum levels of glutamine‐pyruvate transaminase (GPT), lactate dehydrogenase (LDH), ferritin, and triglycerides were quantified using Roche Modular Analytics Evo. Soluble CD25 in serum was determined using IL‐2Ralpha DuoSet kit (R&D Systems), and serum IFNγ was determined with mouse IFN‐gamma ELISA MAX (Biolegend).
Weißert K., Ammann S., Kögl T., Dettmer‐Monaco V., Schell C., Cathomen T., Ehl S, & Aichele P. (2022). Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH). EMBO Molecular Medicine, 14(12), e16085.
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2

Assessing Liver Injury Post-Trauma

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Post‐injury serum samples were collected to assess the extent of liver injury using alanine transaminase assay (P800; Modular Analytics EVO, Roche, Mannheim, Germany). The results were analyzed and displayed with GraphPad Prism software, representing the mean and standard deviation and analyzed using two-sided Student’s t-test. (GraphPad Software Inc., La Jolla, CA, USA).
Melin N., Sánchez-Taltavull D., Fahrner R., Keogh A., Dosch M., Büchi I., Zimmer Y., Medová M., Beldi G., Aebersold D.M., Candinas D, & Stroka D. (2021). Synergistic effect of the TLR5 agonist CBLB502 and its downstream effector IL-22 against liver injury. Cell Death & Disease, 12(4), 366.
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3

Maternal and Fetal Blood Sampling Protocol

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Maternal venous blood was collected at 24 and 34 weeks of gestation and during labor. Umbilical venous blood samples were collected within 30 minutes after placental delivery from a double-clamped section of umbilical cord. EDTA and serum collection tubes were used (Vacutainer: 368857 and 367953) for hematological assessment and biochemical analyses respectively. Blood samples for serum preparation were left at 4 C for 15 minutes to allow blood clotting, centrifuged at 3500 rpm for 10 minutes, and the serum fraction transferred into sterile tubes. Samples were stored at 4 C for same-day analyses or at –80 C for further analysis. Hematological parameters were analyzed using a hematology analyzer (Sysmec XE-2100, Roche Diagnostics) and flow cytometer (Advia 120-160858, Bayer HealthCare). Plasma glucose and triglycerides were measured enzymatically (Modular Analytics EVO, Roche), whereas serum leptin concentrations measured by ELISA (Biosource Kap 2281).
Martino J., Sebert S., Segura M.T., García-Valdés L., Florido J., Padilla M.C., Marcos A., Rueda R., McArdle H.J., Budge H., Symonds M.E, & Campoy C. (2015). Maternal Body Weight and Gestational Diabetes Differentially Influence Placental and Pregnancy Outcomes. The Journal of Clinical Endocrinology and Metabolism, 101(1), 59-68.
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4

Liver Injury Assessment Post-Hepatectomy

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Serum samples post partial hepatectomy were collected to assess the extent of liver injury using aspartate aminotransferase (AST) and alanine transaminase assay (Modular Analytics EVO, P800; Roche, Germany).
Kudira R., Malinka T., Kohler A., Dosch M., de Agüero M.G., Melin N., Haegele S., Starlinger P., Maharjan N., Saxena S., Keogh A., Stroka D., Candinas D, & Beldi G. (2016). P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration. Hepatology (Baltimore, Md.), 63(6).
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