Gemini tf

Manufactured by Philips

Sourced in United States

The Gemini TF is a high-performance analytical instrument manufactured by Philips. It is designed for materials analysis, offering advanced imaging and spectroscopy capabilities. The Gemini TF provides users with versatile and accurate data collection to support a wide range of research and industrial applications.

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Lab products found in correlation

Ingenuity tf, by Philips (9 mentions) Gemini gxl, by Philips (3 mentions) Biograph mct, by Siemens (3 mentions) Discovery mi, by GE Healthcare (2 mentions) Discovery st, by GE Healthcare (2 mentions) Discovery ste, by GE Healthcare (2 mentions) Omnipaque 300, by GE Healthcare (2 mentions) Biograph mct 64, by Siemens (2 mentions) 18f flutemetamol, by GE Healthcare (1 mentions) Intera, by GE Healthcare (1 mentions) Ge discovery 690, by GE Healthcare (1 mentions) Ge discovery mi, by GE Healthcare (1 mentions) Ge discovery 710, by GE Healthcare (1 mentions) Biograph truepoint 64, by Siemens (1 mentions) Pmod 3, by PMOD Technologies (1 mentions) Matlab 2016a, by MathWorks (1 mentions) Discovery 600, by GE Healthcare (1 mentions) Biograph truev, by Siemens (1 mentions) Gemini xl, by Philips (1 mentions) Biograph hi rez, by Siemens (1 mentions)

Spelling variants of this product

Gemini TF 16 (37 citations) Gemini TF 64 scanner (8 citations) GEMINI TF BIG BORE PET/CT (7 citations) Gemini TF PET/CT system (7 citations) Gemini TF 16 PET/CT scanner (6 citations) Gemini TF TOF 64 (5 citations) Gemini TF-II (2 citations) Gemini TF CT scanner (2 citations) GEMINI TF Big Bore PET/CT system (2 citations) Gemini TF Big Bore PET/CT scanner (2 citations)

74 protocols using gemini tf

Multimodal Imaging Protocol for Prostate Cancer

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Contrast-enhanced PET/CT imaging was performed 1 h after injecting 111-148 MBq (3-4 mCi) of 68 Ga-PSMA-HBED-CC. Imaging was performed on Philips Gemini TF (Philips, The Netherlands) at 512 × 512 matrix for CT at 300 mAs and 120 kV and for 2 min/bed position at 144 × 144 matrix for PET. The images were acquired from base of skull to mid-thigh. The images are reconstructed using RAMLA reconstruction algorithm.
Fluorine-18 sodium fluoride PET/computed tomography scan protocol PET/CT imaging was performed 60 min after injecting 5 MBq/Kg 18 F-NaF, intravenously. Imaging was performed on Philips Gemini TF (Philips, The Netherlands) PET/ CT scanner. PET emission images were obtained in a 3-dimensional mode at 2 min/bed position at 144 × 144 matrix. The CT was acquired at 300 mAs and 120 kV and reconstructed in a 512 × 512 matrix with a thickness of 3.75 mm. The images are reconstructed using RAMLA reconstruction algorithm. Thin reconstruction in bone algorithm was done as and when needed. PET-CT and fusion images were reviewed on an Extended Brilliance Workspace (EBW) Philips workstation, version V4.5.3.40140.

Agrawal A., Natarajan A., Mithun S., Bakshi G., Joshi A., Murthy V., Menon S., Purandare N., Shah S., Puranik A., Choudhury S., Prakash G., Pal M., Maitre P., Prabhash K., Noronha V, & Rangarajan V. (2022). Bone metastases in prostate cancer - Gallium-68-labeled prostate-specific membrane antigen or Fluorine 18 sodium fluoride PET/computed tomography - the better tracer?. Nuclear medicine communications, 43(12).

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Amyloid PET Imaging Protocol

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Ninety minutes after [18F]flutemetamol (GE Healthcare, Chicago, IL, USA) intravenous injection (target activity 185 ± 5 MBq), a 30-min list-mode PET/CT acquisition was performed using a Philips Gemini TF (Philips Healthcare, Amsterdam, The Netherlands). The images were reconstructed as a dynamic scan of 6 × 5 min frames with 2 mm isometric voxels, including attenuation, scatter, and decay corrections, in addition to time-of-flight information using the manufacturer’s standard reconstruction algorithm. No partial volume correction was applied to the data.

Colmant L., Boyer E., Gerard T., Sleegers K., Lhommel R., Ivanoiu A., Lefèvre P., Kienlen-Campard P, & Hanseeuw B. (2024). Definition of a Threshold for the Plasma Aβ42/Aβ40 Ratio Measured by Single-Molecule Array to Predict the Amyloid Status of Individuals without Dementia. International Journal of Molecular Sciences, 25(2), 1173.

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Multimodal Imaging for ASCC Staging

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MRI scanners from different manufacturers were used (1.5-T scanners: Siemens Avanto, Symphony, Aera, Philips Intera and GE Optima and Signa; 3-T scanners: Siemens Trio, and GE Discovery). The routine MRI protocol for staging ASCC included standard T2W images in axial, sagittal, and two oblique directions. The slice thickness in axial T2W was in the range of 3–5 mm. When analyzing the LNs, the axial (non-oblique) T2W sequence was primarily used.
PET-CT acquisitions were performed using one of two different equipment: Discovery MI (GE Healthcare, Milwaukee, WI, USA), and Philips Gemini TF (Philips Healthcare, Cleveland, OH, USA). Fasting for at least 4 h before the examination and a glucose level ≤ 180 mg/dl was required. The accumulation time, defined as the duration between intravenous injection of 4 MBq/kg body weight of 18F-FDG and the initiation of image acquisition, was uniformly set at 60 min for all subjects. A PET scan was performed from the upper thighs to the base of the skull. In our clinical protocol, attenuation correction and anatomical correlation of PET images for radiotherapy treatment planning were conducted through either a diagnostic CT with intravenous and oral contrast or a low-dose CT without contrast. Integration with a low-dose CT was implemented when a diagnostic CT had not been performed within the preceding four weeks.

Gulevski S., Frennered A., Trägårdh E., Nilsson M.P., Johnsson A., Buchwald P., Blomqvist L, & Zackrisson S. (2024). MRI morphological characteristics of lymph nodes in anal squamous cell carcinoma. Abdominal Radiology (New York), 49(4), 1042-1050.

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FDG-PET/CT Imaging Protocol for Bladder Cancer Staging

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The Department of Medical Imaging and Physiology at Skåne University Hospital in Lund/Malmö, Kristianstad County Hospital, and Växjö County Hospital, Sweden, conducted the FDG-PET/CT scans. The systems used were Philips Gemini TF (Philips Medical Systems, Cleveland, OH), GE Discovery 690 (GE Healthcare, Milwaukee, WI, USA), GE Discovery 710 (GE Healthcare, Milwaukee, WI, USA) or GE Discovery MI (GE Healthcare, Milwaukee, WI, USA). To decrease the concentration of FDG in the urinary tract, a diuretic (intravenous furosemide 20 mg) was administrated at the same time as ¹⁸F-FDG (4 MBq/kg), and imaging was performed 120 min after radiopharmaceutical administration (Anjos et al. 2007 (link)). The patients were scanned from the inguinal region to the base of the skull. CT images were acquired for attenuation correction and anatomic correlation of the PET images. A diagnostic CT with intravenous and oral contrast or a low-dose CT without contrast was performed. A low-dose CT was chosen in 51/157 (32%) of the patients when a previous diagnostic CT was performed within 4 weeks of the FDG-PET/CT scan, and thus, no direct comparison between the CT and FDG-PET/CT was feasible. Instead, the outcome measure preoperative lymph node stage in the current study was derived from a reassessment and visual analyses by one nuclear medicine physician and one radiologist at the MDT prior to RC.

Pihl V., Markus M., Abrahamsson J., Bläckberg M., Hagberg O., Kollberg P., Simoulis A., Trägårdh E, & Liedberg F. (2023). FDG-PET/CT for lymph node staging prior to radical cystectomy. European Journal of Hybrid Imaging, 7, 13.

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Multimodal CT Imaging Protocol Comparison

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Training CT scans were acquired using an integrated PET/CT system (Biograph Truepoint 64; Siemens Healthineers, Erlangen, Germany). A low-dose CT scan (64-slice helical, 120 kVp, 30 mAs, 512 × 512 matrix) was obtained from the base of the skull to the mid-thigh, with a slice thickness was 3 mm. The test CT scans were acquired using an integrated PET/CT system (Philips Gemini TF, Philips Healthcare, Best, The Netherlands). A low-dose CT scan (16-slice helical, 120 kV, 50–300 mAs based on the patient’s total body mass, 512 × 512 matrix) was obtained from the base of the skull to the mid-thigh, with a slice thickness was 5 mm. The test set included CT scans obtained both with and without intravenous and/or oral contrast agents. The training and separate test studies were obtained from two different hospitals, Sahlgrenska University Hospital, Gothenburg, Sweden and Skåne University Hospital, Malmö/Lund, Sweden respectively. The PET images were not used in this study.

Borrelli P., Kaboteh R., Enqvist O., Ulén J., Trägårdh E., Kjölhede H, & Edenbrandt L. (2021). Artificial intelligence-aided CT segmentation for body composition analysis: a validation study. European Radiology Experimental, 5, 11.

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PET/CT Imaging for Cancer Diagnosis

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Baseline PET/CT examination was performed within 2 weeks before biopsy and CCRT. During the study, PET/CT images was acquired using two whole-body PET/CT scanners; the Philips Gemini TF (Phillips Medical Systems, Holland) was used at the Shandong First Medical University Affiliated Cancer Hospital and Philips ingenuity TF (Phillips Medical Systems, Holland) was used at the Xinjiang Medical University Affiliated Cancer Hospital. The patients fasted for more than 6 h, and their blood glucose levels were measured to ensure a level of < 140 mg/dL. The patients received ¹⁸F-FDG intravenously at a dose of 4.4 MBq/kg; whole-body PET and CT scans were performed one hour later. Spiral CT scans (dose modulation with a quality reference of 150 mAs, 130 kV, a 512 × 512 matrix, and 3-mm slice thickness) were performed immediately prior to the PET scans (1 min in each bed; 144 × 144 matrix); images were acquired from the distal femur to the top of the skull. The PET images were attenuated, corrected, and reconstructed using an iterative ordered subset expectation maximization method. The PET images were then fused with CT images to obtain whole-body transverse, coronal, and sagittal images. All images were acquired using the respiratory gating technique.

Liu H., Cui Y., Chang C., Zhou Z., Zhang Y., Ma C., Yin Y, & Wang R. (2024). Development and validation of a 18F-FDG PET/CT radiomics nomogram for predicting progression free survival in locally advanced cervical cancer: a retrospective multicenter study. BMC Cancer, 24, 150.

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Standardized NaF PET/CT Imaging Protocol

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NaF-PET/CT scans were acquired in accordance with EANM guidelines, which include quality control, calibration and harmonization of the scanner and SUV calculations [19, (link)20] (link). The scanners underwent regular quality and calibration control that fully met all EARL requirements. NaF PET/CT was performed using the hybrid PET/CT scanners Philips Gemini TF (Philips, Amsterdam, Netherlands) and GE STE/VCT/Rx/690PET/CT (GE, Milwaukee, WI). PET images were acquired 45 min after intravenous NaF administration with an acquisition time of 2.5 min/bed. A low-dose CT (LDCT) scan was used for attenuation correction and followed by a 3-D PET scan using a 'whole-body' (base of skull to mid-thigh) acquisition protocol.

Zirakchian Zadeh M., Østergaard B., Raynor W.Y., Revheim M.E., Seraj S.M., Acosta-Montenegro O., Ayubcha C., Yellanki D.P., Al-Zaghal A., Nielsen A.L., Constantinescu C.M., Gerke O., Werner T.J., Zhuang H., Abildgaard N., Høilund-Carlsen P.F, & Alavi A. (2020). Comparison of ¹⁸F-sodium fluoride uptake in the whole bone, pelvis, and femoral neck of multiple myeloma patients before and after high-dose therapy and conventional-dose chemotherapy. European journal of nuclear medicine and molecular imaging, 47(12).

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PET-CT Imaging in Cancer Treatment

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Two different PET-CT systems were used for image acquisition: Discovery MI (GE Healthcare, Milwaukee, WI, USA) and Philips Gemini TF (Philips Healthcare, Cleveland, OH, USA). Patients were in general examined on the same PET-CT system both before and after treatment. Time-of-flight was used on all systems. Patients received 4 MBq/kg body weight of [ 18 F]FDG intravenously. Accumulation time was 60 min before imaging. Fasting for at least 4 h before the examination and a glucose level ≤ 180 mg/dl was required.
For the baseline examination, a PET scan was performed from the upper thigh level to the base of the skull. A high-dose CT from the abdomen to upper thigh level for radiotherapy treatment dose planning, anatomic orientation and attenuation correction was usually performed, complemented by a low-dose CT from the base of the skull to the thorax.
For the follow-up examinations, a whole-body PET from the upper thigh level to the base of the scull was performed, either combined with a low-dose CT or a diagnostic CT with intravenous and oral contrast.

Markus M., Sartor H., Bjurberg M, & Trägårdh E. (2023). Metabolic parameters of [¹⁸F]FDG PET-CT before and after radiotherapy may predict survival and recurrence in cervical cancer. Acta oncologica (Stockholm, Sweden), 62(2).

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PET/CT Imaging of Acute Myocardial Infarction

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All participants underwent ¹⁸F-FDG PET/CT after overnight fasting. Participants with AMI, all of whom were treated with percutaneous coronary intervention successfully, took ¹⁸F-FDG PET/CT within 10 days after AMI onset when they were clinically stable. The image acquisition was started 60 min after injection of 5.29 MBq/kg ¹⁸F-FDG using a dedicated PET/CT scanner (GEMINI TF, Philips Medical Systems, Cleveland, OH, USA), which is composed of a lutetium-yttrium oxyorthosilicate full-ring time-of-flight capable PET and 16-slice helical CT. The scanning range covered the area from the skull base to the proximal thigh. The CT scan was performed first for attenuation correction and localization (4 mm thickness; 120 kVp; 50mA). Immediately after the CT scan, the PET scan was performed for 9 bed positions at 1 min per bed position (4.4 mm spatial resolution with 18 cm axial field of view). All the PET images were reconstructed by the iterative algorithm (three-dimensional row-action maximum likelihood algorithm), using the CT-based attenuation maps.

Pahk K., Kim E.J., Kwon H.W., Joung C., Seo H.S, & Kim S. (2021). Association of Inflammatory Metabolic Activity of Psoas Muscle and Acute Myocardial Infarction: A Preliminary Observational Study with 18F-FDG PET/CT. Diagnostics, 11(3), 511.

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Whole-Body FDG-PET/CT Imaging Protocol

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Patients were instructed to fast for at least 6 h before the PET scan. Blood glucose level was measured to ensure that it was <200 mg/dL. ¹⁸F-FDG was administered intravenously at a dosage of 3.7 MBq/kg. Approximately 60±10 min post-injection, a whole-body acquisition was initiated in 6−8 bed positions (1 min/bed) using a hybrid system (PHILIPS Gemini TF, Cleveland, Ohio, USA) that covered the area from the base of the skull to the upper thigh. This was followed by a CT component acquired in non-contrast phase (modulated 100 mAs, 120 kV, slice thickness: 3 mm) for attenuation correction and for anatomical localization purposes. Head acquisition was performed in one bed position (8−10 min/bed).

Song J., Li Z., Chen P., Yu J., Wang F., Yang Z, & Wang X. (2019). A 18FDG PET/CT-based volume parameter is a predictor of overall survival in patients with local advanced gastric cancer. Chinese Journal of Cancer Research, 31(4), 632-640.

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