Eight channel sense head coil

Whole-brain T1-weighted anatomic images were obtained using a Philips 3T Achieva scanner equipped with an eight-channel SENSE-Head coil and using a 3D FFE T1-weighted structural sequence applied in the sagittal plane with 190 1-mm thick slices (TR/TE = 7.6/3.5 ms; acquisition matrix = 256 × 250; the field of view = 256 mm; flip angle = 8°; total acquisition time = 7:23 min). Images were visually inspected for significant motion artifact by trained raters (DJL, WS).
Amygdala nuclei were measured by quantitative morphometric analysis of T1-weighted MRI data using an automated segmentation protocol from FreeSurfer v6.0¹ with a procedure that uses Bayesian inference with a probabilistic atlas derived from manual delineations of the amygdala using ultra-high-resolution ex vivo MRI scans (Saygin et al., 2017 (link)). Bilateral whole amygdala and hippocampal volumes were measured using an automated protocol from FreeSurfer v6.0. The automated segmentation of amygdala nuclei has been validated for standard resolution T1 data of varying MR contrast. The approach takes individual underlying anatomy into account, thus providing greater spatial sensitivity (Saygin et al., 2017 (link)). Segmentations were visually inspected for failures and manually corrected where necessary. All neuroimaging was completed within 1 year of social network data collection.

fMRI data were acquired using a 3.0 Tesla Philips Achieva MRI scanner with an eight-channel SENSE head coil. Whole-brain functional images were acquired using axial oblique slices (tilted 15° anterior higher than posterior relative to the AC-PC line) with an isotropic 2.5-mm³ voxel size (TR = 2 s, TE = 25 ms, flip angle = 90°, acquisition matrix = 96 × 96, no gap). The first two volumes of each functional run were discarded for equilibration. High-resolution anatomical images were acquired in the sagittal plane using a T1-weighted volumetric 3D SPGR sequence (TR = 7.9 ms, TE = 3.7 ms, flip angle = 7°, acquisition matrix: 256 × 256, 1-mm³ isotropic resolution). Foam cushioning between participants’ head and the birdcage coil was used to minimize motion. During the structural, scout, and reference scans, participants watched a preferred video, with the restriction that it could not be related to the topic presented in their own interest condition. During the functional scan, participants were instructed simply to pay attention to each picture. They were informed prior to scanning that they would be tested after the scan regarding how many pictures they remembered.

Magnetic resonance imaging data were acquired on a Philips Achieva 3T scanner equipped with an eight-channel SENSE head coil, including the following scans: (a) sagittal three-dimensional T1-weighted scan (TR = 8.1 ms, TE = 3.7 ms, flip angle = 6°, acquisition matrix = 256 × 256 × 160, field of view = 256 mm × 256 mm × 160 mm, voxel size = 1 mm × 1 mm × 1 mm, and SENSE factor of 2 along the left–right direction); (b) sagittal three-dimensional FLAIR (TR = 8000 ms, TI = 2400 ms, TE = 337 ms, flip angle = 6°, acquisition matrix = 256 × 256 × 160, field of view = 256 mm × 256 mm × 160 mm, voxel size = 1 mm × 1 mm × 1 mm, and SENSE factor of 2 along the left–right direction and 2.5 along the anterior–posterior direction); and (c) multi-echo SWI using an axial 3D gradient echo scan (TR = 36 ms, TE = 6/12/18/24/30 ms, flip angle = 17°, acquisition matrix = 440 × 222 × 64, field of view = 220 mm × 166 mm × 128 mm, acquired voxel size = 0.5 mm × 0.5 mm × 2 mm, reconstructed voxel size = 0.5 mm × 0.5 mm × 1 mm, and SENSE factor of 1.2 along the left–right direction) (8 (link)).

The experiment was conducted on a 3 Tesla scanner (Philips Achieva), equipped with an eight-channel SENSE-head coil. Stimuli were projected on a screen behind the scanner, which participants viewed via a mirror mounted on the head-coil. T2*-weighted functional images were acquired using a gradient-echo echo-planar imaging sequence. An acquisition time of 2000 ms was used (image resolution: 3.03 × 3.03 × 4 mm³, TE = 30, flip angle = 90°). After the functional runs were completed, a high-resolution T1-weighted structural image was acquired for each participant (voxel size = 1 × 1 × 1 mm³, TE = 3.8 ms, flip angle = 8°, FoV = 288 × 232 × 175 mm³). Four dummy scans (4 ×2000 ms) were routinely acquired at the start of each functional run and were excluded from analysis.

Functional MR images were acquired at the Sir Peter Mansfield Imaging Centre, University of Nottingham, using a Philips Achieva 3.0-Tesla scanner equipped with an eight-channel SENSE head coil. Structural images were acquired using 3D MPRAGE sequence (1 mm³ isotropic resolution, repetition time (TR)/echo time (TE) = 8.278/2.3 ms, flip angle = 8°, 160 slices, FOV = 256 mm × 256 mm). For functional images, echo-planar imaging (EPI) sequence (TR/TE = 2,000/35 ms, flip angle 90°, 32 slices, FOV = 240 mm × 240 mm, voxel size = 3 mm × 3 mm × 3 mm) was used for the task and resting conditions.

Adults participated in a magnetic resonance imaging (MRI) scan in a Philips Achieva 3-Tesla scanner (Philips Medical Systems, Inc., Best, Netherlands) using an eight-channel SENSE head coil, housed in the Vanderbilt University Institute of Imaging Science (Nashville, TN, USA). High-resolution three-dimensional anatomical T1-weighted MRI images were acquired using a turbo field echo sequence with full brain coverage and the following parameters: field of view = 256 × 256 mm²; in plane voxel resolution = 1 × 1 mm²; repetition time = 8.9 ms; echo time = 4.6 ms; flip angle = 8°; slice thickness = 1 mm and 170 slices with no slice gap.