Achieva 3t mri

Manufactured by Philips

The Achieva 3T MRI is a magnetic resonance imaging (MRI) system developed by Philips. It operates at a magnetic field strength of 3 Tesla, which allows for high-quality imaging and detailed visualization of the body's internal structures. The Achieva 3T MRI is designed to provide advanced imaging capabilities for a wide range of clinical applications.

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Lab products found in correlation

Spinlab, by GE Healthcare (1 mentions) 32 channel cardiac coil, by Philips (1 mentions)

5 protocols using achieva 3t mri

Automated Structural MRI Processing Pipeline

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All neuroimaging data were collected on a Philips Achieva 3T MRI at the University of Florida (Philips Electronics, Amsterdam, The Netherlands) at the McKnight Brain Institute (University of Florida, Gainesville, FL) with a 32-channel receive-only head coil. A high-resolution T1-weighted MPRAGE whole-brain T1 image was acquired in 170 interleaved sagittal 1mm slices (TR=7.0ms, TE=3.2ms, FOV=240² mm). Structural T1 data were examined for imaging artifacts, and subsequently processed through the FreeSurfer version 6.0.0 automated pipeline(Fischl et al., 2002 (link)). Freesurfer output was manually inspected by trained research staff. During this process, data were reviewed in a manner consistent with Freesurfer documentation and previously validated against histological measures (Cardinale et al., 2014 (link)). In this process control points are added when necessary to ensure accurate delineation of tissue types throughout the brain (Morey et al., 2009 (link)). The resulting segmentation data for grey and white matter volumes from this process were then utilized for further analysis in the present study (labeled “MR Volumes” hereafter) through the use of machine learning models predicting cognitive function.

Gullett J.M., Chen Z., O’Shea A., Akbar M., Jiang B., Rani A., Porges E.C., Foster T., Woods A.J., Modave F, & Cohen R.A. (2020). Micro RNA Predicts Cognitive Performance in Healthy Older Adults. Neurobiology of aging, 95, 186-194.

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In Vivo Hyperpolarized [1-^13C] NAC Imaging

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NaOH (5 M) was added to [1-¹³C] NAC powder and OX063 to produce a 3.2 M [1-¹³C] NAC solution with 17 mM OX063 at pH of 7.5. 35 mL of 3.2 M [1-¹³C] NAC with 17 mM OX063 was hyperpolarized using the SPINlab (GE Healthcare) for 3–4 h, and the scans were performed using the Philips Achieva 3 T MRI. ¹³C two dimensional spectroscopic chemical shift images (CSIs) were acquired with a 28 × 28 mm, field of view in a 10 mm axial slice through the head, a matrix size of 14 × 14, spectral width of 3333 Hz, repetition time of 86 ms, and excitation pulse width a flip angle of 3° for the mouse head, and with a 32 × 32 mm, field of view in a 10 mm coronal slice through the body, a matrix size of 16 × 16, spectral width of 3333 Hz, repetition time of 85 ms, and excitation pulse with a flip angle of 10° for the mouse body. CSIs were acquired 30 s after the beginning of the hyperpolarized [1-¹³C] NAC injections.

Yamamoto K., Opina A., Sail D., Blackman B., Saito K., Brender J.R., Malinowski R.M., Seki T., Oshima N., Crooks D.R., Kishimoto S., Saida Y., Otowa Y., Choyke P.L., Ardenkjær-Larsen J.H., Mitchell J.B., Linehan W.M., Swenson R.E, & Krishna M.C. (2021). Real-Time insight into in vivo redox status utilizing hyperpolarized [1-13C] N-acetyl cysteine. Scientific Reports, 11, 12155.

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Volumetric Brain Imaging at 10 Years

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Resonance images were obtained at 10 years of age, when the brain typically attained 95 % of its adult volume (28) . Children were scanned using a Philips Achieva 3T MRI (Philips Medical Systems, Best, Netherlands) scanner operating with an eight-channel, phased-array head coil for reception. T1-weighted threedimensional (3D) volumes were acquired using a T1-weighted 3D-turbo-gradient field echo sequence (3D-TFE), in sagittal orientation with 0•94 × 0•94 × 1•0-mm resolution (160 slides, Field of View (FOV) = 240 × 240, matrix 256 × 256 × 160), with repetition time of 8 ms, echo time of 4 ms, inversion delay of 1022•6264 ms, flip angle of 8°and band width of 191 Hz/pixel. The sequence was optimal for reducing motion sensitivity, susceptibility artefacts and field inhomogeneities. Total volumes for grey and white matter (GMV and WMV) and total intracraneal volume (TIV, obtained from GM, WM and cerebrospinal fluid (CSF) voxels in native space) were computed for each child adding up to the corresponding voxel values.

Catena A., Martínez-Zaldívar C., Diaz-Piedra C., Torres-Espínola F.J., Brandi P., Pérez-García M., Decsi T., Koletzko B, & Campoy C. (2019). On the relationship between head circumference, brain size, prenatal long-chain PUFA/5-methyltetrahydrofolate supplementation and cognitive abilities during childhood. The British journal of nutrition, 122(s1).

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Multimodal Breathing Assessment with MRI

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The MR exam consisted of chemical shift-encoded (CSE) MRI (also known as Dixon imaging) of the chest and abdominal musculature as well as dynamic MRI (a single slice imaged repeatedly over time) while participants performed breathing maneuvers as described below. All MR data were acquired using a Philips 3T Achieva MRI (Philips, Amsterdam, Netherlands) with a 32-channel cardiac coil. For imaging of the chest, participants were positioned in supine with the coil centered over the heart, ensuring coil coverage over the entirety of the lungs. CSE imaging of the chest utilized a four-lead VCG (VectorCardioGraphy) signal and a respiratory pillow to gate image acquisition. This allowed for free-breathing imaging. For abdominal imaging, the coil was centered over the umbilicus, and gating was not required. Participants were able to watch a movie or listen to music during the scan session (approximately 40–50 minutes in length).

Barnard A.M., Lott D.J., Batra A., Triplett W.T., Forbes S.C., Riehl S.L., Willcocks R.J., Smith B.K., Vandenborne K, & Walter G.A. (2019). Imaging Respiratory Muscle Quality and Function in Duchenne Muscular Dystrophy. Journal of neurology, 266(11), 2752-2763.

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Multi-Modal Imaging of Macaque Anatomy

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Macaques were scanned with a Phillips 3 T Achieva MRI. All scans were obtained with respiratory gating. Baseline structural T2-W 3-D turbo spin echo images (TR/TE = 2500/250 ms, resolution 1 mm³, matrix 452 × 226), QT2 2-D turbo spin echo images (TR/TE = 5000/12 + 12n [n = 0–8], in-plane resolution 0.94 mm², matrix 228 × 113, slice thickness 4 mm), and 3-D quantitative T2* (3-D fast field echo sequence, TR/TE = 75/6.9 + 6.9n [n = 0–8], resolution 0.94 × 0.94 × 4 mm³, matrix 228 × 228 × 113) were obtained in coronal orientation over a body region spanning from the top of the head to the pelvis. 3-D T2*-W images were obtained of the head only, in an oblique plane (TR/TE = 45/25 ms, resolution 0.89 × 0.89 × 4 mm³, matrix 100 × 100). Interleaved scanning of brain (T2*-W) and head/torso (QT2) was performed after nanoparticle administration. Scan times were 6.2 min (T2W structural image) 20.3 min (QT2 image) 1.9 min (T2*-W image).

Chiarelli P.A., Revia R.A., Stephen Z.R., Wang K., Jeon M., Nelson V., Kievit F.M., Sham J., Ellenbogen R.G., Kiem H.P, & Zhang M. (2017). Nanoparticle Biokinetics in Mice and Nonhuman Primates. ACS nano, 11(9), 9514-9524.

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