Sepin-1 (2,2-dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide) with >97% purity was purchased from ChemBridge (San Diego, CA, United States). Phenacetin, efavirenz, paclitaxel, (S)-mephenytoin, quercetin, α-naphthoflavone, ticlopidine, ketoconazole, sulfaphenazole, and dextromethorphan were purchased from Cayman Chemical (Ann Arbor, MI, United States). Reduced GSH, diclofenac sodium, quinidine, midazolam solution, formic acid, and NADPH were obtained from Sigma-Aldrich (St. Louis, MO, United States). HLM, MLM, and RLM, and the recombinant human CYP450s (EasyCYP Bactosomes) were purchased from XenoTech (Lenexa, KS, United States). All the solvents for LC and MS were of the highest grade commercially available.
Efavirenz
Manufactured by Cayman Chemical
Sourced in United States
Efavirenz is a pharmaceutical compound used as an active ingredient in various laboratory applications. It functions as a non-nucleoside reverse transcriptase inhibitor (NNRTI) that blocks the activity of the HIV-1 reverse transcriptase enzyme, an essential component of the HIV replication process. Efavirenz is commonly utilized in research and development settings for the study of HIV/AIDS treatment and related therapeutic interventions.
Automatically generated - may contain errors
Lab products found in correlation
Diclofenac sodium, by Merck Group (1 mentions)
Paclitaxel, by Cayman Chemical (1 mentions)
Quercetin, by Cayman Chemical (1 mentions)
Ketoconazole, by Cayman Chemical (1 mentions)
Sulfaphenazole, by Cayman Chemical (1 mentions)
Quinidine, by Merck Group (1 mentions)
Reduced gsh, by Merck Group (1 mentions)
Sepin 1, by ChemBridge (1 mentions)
S mephenytoin, by Cayman Chemical (1 mentions)
α naphthoflavone, by Cayman Chemical (1 mentions)
Dextromethorphan, by Cayman Chemical (1 mentions)
Formic acid, by Merck Group (1 mentions)
Nadph, by Merck Group (1 mentions)
Saquinavir, by Cayman Chemical (1 mentions)
Enfuvirtide, by Merck Group (1 mentions)
Emtricitabine, by Abcam (1 mentions)
Lamivudine, by Targetmol (1 mentions)
2 protocols using efavirenz
1
In Vitro Enzymatic Characterization
2
Antiretroviral Drug Combination Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
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Enfuvirtide (T-20; SML0934) was purchased from Sigma-Aldrich, Emtricitabine (FTC; ab145045) from abcam, Abacavir (ABC; Cay14746-10) from Biomol, Lamivudine (3TC; T0682) and Dolutegravir (DTG; T6198) from TargetMol, Efavirenz (EFV; 14412) and Saquinavir (SQV; 9001893) from Cayman.
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