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1 2 dimyristoyl sn glycero 3 phosphocholine

Manufactured by NOF corporation
Sourced in Japan, United States

1,2-dimyristoyl-sn-glycero-3-phosphocholine is a synthetic phospholipid that is commonly used in research applications. It is a zwitterionic lipid that is composed of two myristic acid chains attached to a glycerol backbone, with a phosphocholine headgroup. The core function of this product is to serve as a model membrane component for the study of lipid bilayer properties and interactions.

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3 protocols using 1 2 dimyristoyl sn glycero 3 phosphocholine

1

Lipid Compounds for Biomembrane Studies

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The compounds 1-palmitoyl-2-oleoyl-glycero-3phosphocholine (POPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) were purchased from NOF corporation (White Plains, NY, USA). The compound 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[azido(polyethylene glycol)-2000] (DSPE-PEG2k) was purchased from Avanti Polar Lipids (Alabaster, AL, USA). Lipopolysaccharide (LPS) (E. coli O111:B4) was purchased from Sigma Aldrich (St. Louis, MO, USA). Cholesterol was purchased from Sigma Aldrich (Milwaukee, WI, USA). Wako Cholesterol E Kit was purchased from Fujifilm (Richmond, VA, USA). IL-6 and TNF-α ELISA kits were purchased from Invitrogen (Ann Arbor, MI, USA).
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2

DMPC, PG, and Castor Oil Formulation

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1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) was purchased from NOF CORPORATION (Tokyo, JP), propylene glycol (PG) from Polioles S.A. de C.V. (Mexico City, MX) and castor oil from Textron (Providence, RI, US).
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3

Lipid Bilayer Membrane Preparation

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FD-4 was obtained from Sigma-Aldrich (St. Louis, MO, USA). 1,2-Dimyristoylsn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), and 1,2-dioleoyl-snglycero-3-phosphocholine (DOPC) were purchased from NOF Corporation (Tokyo, Japan). MGE was kindly provided by Farnex Inc. (Yokohama, Japan). Polyoxyethylene sorbitan monooleate (Tween 80) was obtained from Tokyo Chemical Industry (Tokyo, Japan). All other regents were used without further purification.
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