Peripheral venous blood was obtained under sterile conditions from patients prior to treatment (on cycle 1, day 1, predose) and every 3 weeks thereafter. Serum was separated by centrifuging for 10 min at 1000 g and 4°C in vacuum gel tubes, and then kept at –80°C until the time of assay. CRP was analyzed by routine clinical laboratory test protocols utilizing an automated chemical analyzer using the high sensitivity Siemens HS-CRP assay for this study, though in practice any validated CRP assay can be used since a time-dependent relative ratio method is used, as described below.
Hs crp assay
Manufactured by Siemens
The HS-CRP assay is a laboratory instrument used for the measurement of high-sensitivity C-Reactive Protein (HS-CRP) levels in human blood samples. HS-CRP is a biomarker that can indicate the presence of inflammation or infection in the body. The HS-CRP assay provides quantitative results that can be used by healthcare professionals as part of the clinical assessment process.
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Lab products found in correlation
2 protocols using hs crp assay
1
Serum CRP Analysis Protocol
2
Serum hsCRP Measurement Protocol
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The Siemens Atellica hsCRP assay was used to measure hsCRP levels in stored serum. The assay range is from 0.1 to 50 mg/L with a coefficient of variation of 6.8% at 1.16 mg/L.15
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