Brafi dabrafenib

Manufactured by MedChemExpress

BRAFi Dabrafenib is a laboratory compound used for research purposes. It is a selective inhibitor of BRAF kinase, a key component of the MAP kinase/ERK signaling pathway. This product is intended for scientific research use only and not for use in humans.

Automatically generated - may contain errors

Lab products found in correlation

Hx531, by Bio-Techne (2 mentions) Smartpool sirna, by Horizon Discovery (2 mentions) Meki trametinib, by MedChemExpress (2 mentions) Faki pf562271, by MedChemExpress (2 mentions) Recombinant gdnf, by Thermo Fisher Scientific (2 mentions)

2 protocols using brafi dabrafenib

Evaluating Targeted Therapeutic Combinations

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BRAFi Dabrafenib, MEKi Trametinib and FAKi PF562271 were purchased from MedChemExpress, RXR antagonist HX531 from Tocris, siRNA SMARTpools from Dharmacon (siRNA sequences are available upon request), recombinant GDNF from Peprotech.

Marin-Bejar O., Rogiers A., Dewaele M., Femel J., Karras P., Pozniak J., Bervoets G., Van Raemdonck N., Pedri D., Swings T., Demeulemeester J., Borght S.V., Lehnert S., Bosisio F., van den Oord J.J., Bempt I.V., Lambrechts D., Voet T., Bechter O., Rizos H., Levesque M.P., Leucci E., Lund A.W., Rambow F, & Marine J.C. (2021). Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma. Cancer cell, 39(8).

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Evaluating Targeted Therapeutic Combinations

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Marín-Béjar O., Rogiers A., Dewaele M., Femel J., Karras P., Poźniak J., Bervoets G., Raemdonck N.V., Pedri D., Swings T., Demeulemeester J., Pelt J.v., Bosisio F.M., Oord J.J.v.d., Bempt I.V., Lambrechts D., Voet T., Bechter O., Rizos H., Levesque M.P., Leucci E., Lund A.W., Rambow F., & Marine J. (2020). A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanoma.

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