Piperazine pip

Manufactured by Merck Group

Piperazine (PiP) is a chemical compound commonly used in the pharmaceutical and chemical industries. It is a cyclic diamine with the chemical formula C4H10N2. Piperazine serves as a core building block for various pharmaceutical and chemical products, but a detailed description of its specific applications or intended use is not provided here to maintain an unbiased and factual approach.

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Lab products found in correlation

Chloroform, by Avantor (1 mentions) Acetonitrile, by Avantor (1 mentions) Methanol, by Avantor (1 mentions) Super q water system, by Merck Group (1 mentions) Bovine serum albumin (bsa), by Merck Group (1 mentions) Trimesoyl chloride tmc, by Merck Group (1 mentions) Milli q system, by Merck Group (1 mentions) Triethylamine, by Merck Group (1 mentions) N hexane, by Merck Group (1 mentions)

3 protocols using piperazine pip

Synthesis of Stimuli-Responsive Hydrogels

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N-Isopropylacrylamide (NiPAAm), glycidyl methacrylate (GMA), 2,2′-azobis(2-methylpropionitrile) (azobisisobutyronitrile, AIBN), N,N′-methylenebisacrylamide (MBA), and piperazine (PiP) were purchased from Sigma-Aldrich (Sigma, St. Louis, MO) and used as received. The solvents−tetrahydrofuran (THF), dimethylformamide (DMF), diethyl ether, and acetone in analytical grade and water, acetonitrile, chloroform, and methanol in HPLC grade–were obtained from VWR (Radnor, PA) and used as received. Phosphate buffered saline (PBS) solution was mixed from powder (pH 7.4, Gibco Life, Grand Island, NY), and ultrapure water was obtained from a Millipore Super-Q water system (Millipore, Billerica, MA).

Tzouanas S.N., Ekenseair A.K., Kasper F.K, & Mikos A.G. (2014). Mesenchymal Stem Cell and Gelatin Microparticle Encapsulation in Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering. Journal of biomedical materials research. Part A, 102(5), 1222-1230.

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Polysulfone Membrane Fabrication and Characterization

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All chemicals were used as received: 1,3,5-benzenetricarboxylic chloride (TMC), (98%, Alfa), piperazine (PIP) (99%, anhydrous, Alfa), BSA (96%, Sigma-Aldrich). Sulfaguanidine (SG) (98%, TCI). Dyes including methyl orange (MO), chrome black T (CBT), rhodamine B (RB), congo red (CR), methyl blue (MB) were purchased from Aladdin Reagent Company (Shanghai, China). Neutral solutes (PEG200, PEG400, PEG600 and PEG1000) and all other reagents such as n-hexane, NaOH, Na₂SO₄, MgSO₄, NaCl, CaCl₂ were of analytical grade and supplied by Kelong Chemical Reagent Factory (Chengdu, China). All chemicals mentioned above were used without further purification. Flat-sheet nonwoven-reinforced polysulfone (PSf) ultrafiltration membranes [molecular weight cut-off (MWCO) = 60 000] as supports were provided by Beijing Haiqingyuan Technology Co. Ltd. Deionized (DI) water with the conductivity less than 3 μs cm⁻¹ was produced by water distiller.

Zhang H.L., Liu B.H., Yang M., Zhang P, & Gai J.G. (2019). Sulfaguanidine nanofiltration active layer towards anti-adhesive and antimicrobial attributes for desalination and dye removal. RSC Advances, 9(36), 20715-20727.

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Fabrication of PVDF-CA Composite Membranes

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Polyvinylidene fluoride (PVDF, Solef 6010, Mw ≈ 320,000) was purchased from Solef (Suzhou, China) and cellulose acetate (CA, Mw ≈ 100,000) was purchased from Sigma-Aldrich (Shanghai, China). N,N-Dimethylacetamide (DMAc, ReagentPlus, 99%) was provided by the China National Pharmaceutical Group Corporation (Beijing, China). Piperazine (PIP, 99%) and trimesoyl chloride (TMC, 98%) were supplied by Sigma-Aldrich. Triethylamine (analytical reagent, TEA), sodium dodecyl sulfate (SDS, Acros), and N-hexane (analytical reagent, 95%) were purchased from Sigma-Aldrich. Deionized water was produced using a Milli-Q system (Millipore, Burlington, MA, USA).

Liu F., Li Y., Han L., Xu Z., Zhou Y., Deng B, & Xing J. (2022). A Facile Strategy toward the Preparation of a High-Performance Polyamide TFC Membrane with a CA/PVDF Support Layer. Nanomaterials, 12(24), 4496.

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