Maxwell rsc whole blood kit

Manufactured by Promega

Sourced in Switzerland

The Maxwell RSC Whole Blood Kit is a laboratory instrument designed for the automated purification of genomic DNA from whole blood samples. It utilizes magnetic particle technology to extract and purify DNA, providing a streamlined and consistent sample preparation process.

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Lab products found in correlation

Maxwell rsc, by Promega (14 mentions) Maxwell rsc instrument, by Promega (7 mentions) Paxgene blood rna kit, by Preanalytix (1 mentions) Maxwell rsc dna ffpe kit, by Promega (1 mentions) Maxwell rsc tissue dna kit, by Promega (1 mentions) Truseq pcr, by Illumina (1 mentions) Truseq pcr free dna library, by Illumina (1 mentions) Maxwell rsc 48, by Promega (1 mentions)

Close spelling variants of this product

Maxwell RSC Maxwell kits

23 protocols using maxwell rsc whole blood kit

DNA Isolation from Feline EDTA Blood

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Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega). Additionally we used DNA from EDTA blood of 171 non-affected control cats of various breeds that had been stored in our biobank.

Hug P., Kern P., Jagannathan V, & Leeb T. (2019). A TAC3 Missense Variant in a Domestic Shorthair Cat with Testicular Hypoplasia and Persistent Primary Dentition. Genes, 10(10), 806.

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Genomic DNA and RNA Isolation

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Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit, using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). Genomic DNA from liver tissue samples of the stillborn puppies was isolated with a proteinase K / phenol-extraction method [32 (link)]. Total RNA was extracted from PAXgene blood samples using the PAXgene Blood RNA Kit (PreAnalytiX GmbH, Hombrechtikon, Switzerland).

Lourdes Frehner B., Christen M., Reichler I.M., Jagannathan V., Novacco M., Riond B., Peters L.M., Suárez Sánchez-Andrade J., Pieńkowska-Schelling A., Schelling C., Kipar A., Leeb T, & Balogh O. (2023). Autosomal recessive hyposegmentation of granulocytes in Australian Shepherd Dogs indicates a role for LMBR1L in myeloid leukocytes. PLOS Genetics, 19(6), e1010805.

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Australian Shepherd Genomic DNA Extraction

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This study included 247 Australian Shepherds. Genomic DNA was either isolated from EDTA blood samples with the Maxwell RSC Whole Blood Kit, or from formalin-fixed paraffin-embedded (FFPE) tissue samples with the Maxwell RSC DNA FFPE Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Kiener S., Laprais A., Mauldin E.A., Jagannathan V., Olivry T, & Leeb T. (2020). LAMB3 Missense Variant in Australian Shepherd Dogs with Junctional Epidermolysis Bullosa. Genes, 11(9), 1055.

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Automated Genomic DNA Extraction from Blood

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Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Gurtner C., Hug P., Kleiter M., Köhler K., Dietschi E., Jagannathan V, & Leeb T. (2020). YARS2 Missense Variant in Belgian Shepherd Dogs with Cardiomyopathy and Juvenile Mortality. Genes, 11(3), 313.

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Genomic DNA Extraction from Blood

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EDTA blood samples were collected for genomic DNA isolation. Genomic DNA was isolated from 500 µL of EDTA blood with the Maxwell RSC Whole-Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Rudd Garces G., Christen M., Loechel R., Jagannathan V, & Leeb T. (2022). FYCO1 Frameshift Deletion in Wirehaired Pointing Griffon Dogs with Juvenile Cataract. Genes, 13(2), 334.

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Hair Shaft Dystrophy in Domestic Cats

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This study included two unrelated domestic shorthair (DSH) cats affected by hair shaft dystrophy, and 61 genetically diverse control cats. The 63 sequenced cats included 34 purebred cats from 11 different breeds and 29 random-bred domestic cats (Table S1). Genomic DNA was isolated from ETDA blood samples with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Kiener S., Rostaher A., Rüfenacht S., Jagannathan V., Sundberg J.P., Welle M, & Leeb T. (2021). Independent DSG4 frameshift variants in cats with hair shaft dystrophy. Molecular Genetics and Genomics, 297(1), 147-154.

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Automated Genomic DNA Extraction from Blood

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Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Rudd Garces G., Turba M.E., Muracchini M., Diana A., Jagannathan V., Gentilini F, & Leeb T. (2021). PRKG2 Splice Site Variant in Dogo Argentino Dogs with Disproportionate Dwarfism. Genes, 12(10), 1489.

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Genomic Analysis of Rough Collies

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Genomic DNA was isolated from EDTA blood with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). Ten Rough Collies consisting of 3 cases and 7 control dogs from an extended family were genotyped on the Illumina canine_HD BeadChips containing 220,853 markers (Neogen, Lincoln, NE, USA).

Hug P., Anderegg L., Kehl A., Jagannathan V, & Leeb T. (2019). AKNA Frameshift Variant in Three Dogs with Recurrent Inflammatory Pulmonary Disease. Genes, 10(8), 567.

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Genomic DNA Extraction from Tissue and Blood

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Genomic DNA was either isolated from frozen liver tissue with a Maxwell RSC Tissue DNA Kit or from ETDA blood samples with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland).

Garcia T.M., Kiener S., Jagannathan V., Russell D.S, & Leeb T. (2020). A COL7A1 Variant in a Litter of Neonatal Basset Hounds with Dystrophic Epidermolysis Bullosa. Genes, 11(12), 1458.

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Genomic DNA Isolation from Golden Retriever and Labrador Families

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Genomic DNA was isolated from EDTA blood of 30 members of an extended Golden Retriever family with the Maxwell RSC Whole Blood Kit using a Maxwell RSC instrument (Promega, Dübendorf, Switzerland). Additionally we used DNA from EDTA blood of 459 non-affected control Labrador Retrievers that had been stored in our biobank.

Hug P., Anderegg L., Dürig N., Lepori V., Jagannathan V., Spiess B., Richter M, & Leeb T. (2019). A SIX6 Nonsense Variant in Golden Retrievers with Congenital Eye Malformations. Genes, 10(6), 454.

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