Linoleoyl ethanolamide

Manufactured by Cayman Chemical

Sourced in United States

Linoleoyl ethanolamide is a chemical compound that serves as a precursor for the synthesis of biologically active lipid mediators. It is a naturally occurring fatty acid derivative that can be used in research applications. This product is intended for laboratory use only.

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2 protocols using linoleoyl ethanolamide

Lipid Compound Characterization and Storage

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The following chemicals were obtained from Cayman Chemical: lin oleic acid (#90150), 2-linoleoyl glycerol (#62260), linoleoyl ethanolamide (#90155), linoleoyl glycine (#9000326), oleic acid (#9000326), 1-oleoyl-2-acetyl-sn-glycerol (OAG, #62600), 2-arachidonoyl glycerol (#62160), 2-arachidonoyl glycerol ether (#62165), R-1 methanandamide (#90070), JZL 184 (#13158) and IDFP (#10215). The chemicals were dissolved in ethanol or DMSO and kept at −80°C. Riluzole [2-Amino-6-(trifluoromethoxy)benzothiazole] (329-92191, FUJIFILM Wako Chemicals) and GSK1702934A (SML2323, Sigma-Aldrich) were dissolved in DMSO and kept at −20°C. Ruthenium red (R2751, Sigma-Aldrich) was dissolved in water and stored at −20°C.

Sokabe T., Bradshaw H.B., Tominaga M., Leishman E., Chandel A, & Montell C. (2022). Endocannabinoids produced in photoreceptor cells in response to light activate Drosophila TRP channels. Science signaling, 15(755), eabl6179.

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Comprehensive Lipidomics Analysis of Bioactive Lipids

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Chemical reagents and HPLC grade organic solvents were purchased from Sigma Aldrich (St. Louis, MO, USA). These include HPLC grade Methanol, Chloroform, Acetonitrile, Isopropanol, Butylated Hydroxytoluene, Ammonium Formate, and Formic Acid. Synthetic lipid standards 21:0–22:6 PC was purchased from Avanti Polar Lipids (Alabaster, AL, USA). Oxylipin standards 9,10-DIHOME, 20-HETE, 9-HETE, 8,9-DHET, 14,15-DHET, 5-HETE, 12-HETE, 11,12-DHET, 5,6-DHET, 13-KODE, 13-HpODE, 9-HpODE, 9-HODE, 9-HoTre, 13-HoTre, 14(15)-EET, 8(9)-EET, 11(12)-EET, 12(13)-EPOME, 13-HODE, Prostaglandin E2, Prostaglandin E2 Ethanolamide, Prostaglandin E2 Glycerol, ARA-Ethanolamide (AEA), 2-AG, Oxy-AEA, Oleamide, Docosanoyl Ethanolamide, Docosahexaneoyl Ethanolamide (DHEA), Lin Oleoyl Ethanolamide (LEA), dihomo-gamma Linolenoyl Ethanolamide, a-Linolenoyl Ethanolamide (ALEA), Resolvin D3, Resolvin D1, Resolvin D2, Resolvin E1, Thromboxane B2, Leukotriene B4, Prostaglandin F2a, 8-Isoprostane, Oleoyl Ethanolamide (OEA), Palmitoyl Ethanolamide (PEA), Stearoyl Ethanolamide (SEA) were purchased from Cayman Chemical (Ann Arbor, MI, USA).

Maner-Smith K.M., Ferranti E., Dunlop A., Corwin E, & Ortlund E.A. (2022). African American Women with Cardiometabolic Complications of Pregnancy Have Decreased Serum Abundance of Specialized Pro-Resolving Lipid Mediators and Endocannabinoids. Nutrients, 15(1), 140.

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