Nah2po4

Chromeazurol S (CAS), hexadecyl trimethyl ammonium bromide (CTAB), and resveratrol were purchased from Shanghai Macklin Biochemical Technology Co., Ltd. (Shanghai, China). Glucose, peptone, NaH₂PO₄, KH₂PO₄, and FeCl₃ were purchased from Tianjin Damao Chemical Reagent Factory (Tianjin, China). MgSO₄·7H₂O, CaCl₂, Na₂HPO₄·12H₂O, NaCl, NH₄Cl, MeOH, and 95% EtOH were obtained from Xilong Science Co., Ltd. (Guangzhou, China). The phosphate buffer solution (PBS) and dimethyl sulfoxide (DMSO) were acquired from Biosharp (Anhui, China). Agar powder was bought from Guangdong Huankai Microbial Technology Co., Ltd. (Guangdong, China), and N-methyl-3-phenyl-2-propen-1-amine was bought from Sigma (MO, USA). (5Z)-4-bromo-5-(bromomethylene)-2(5H)-furanone was kindly presented by Prof. W.M. Chen (Jinan University, China). Hordenine, 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMN), and crystal violet were obtained from Aladdin Biochemical Technology Co., Ltd. (Shanghai, China). Furthermore, P. aeruginosa PAO1 was obtained from Prof. Q.H. Gong (Ocean University of China, China).

ITZ of pharmaceutical grade was purchased from Sanlian Pharmaceutical (Harbin, China), its active metabolite hydroxyitraconazole (OH-ITZ) (purity higher than 99%) was purchased from J&K Scientific Ltd. (Shanghai, China) and used as a reference substance. Commercial Sporanox^® capsules were obtained from Xian Janssen Pharmaceutical Ltd. (Xian, China). d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), Poloxamer 188, and sodium dodecyl sulfate (SDS) were purchased from BASF (Ludwigshafen, Germany), Macklin Biochemical Ltd. (Shanghai, China), and FuchenChemical Reagents Factory (Tianjin, China), respectively. Hydroxypropylmethylcellulose acetate succinate (HPMC AS) (grade LF) was kindly provided by Shin Etsu (Shin-Etsu Chemical Co., Ltd., Tokyo, Japan). The beagle dogs used for in vivo bioavailability study were purchased from the ChaiMen Biological Technology Ltd. (Nanjing, China). HCl was obtained from Jinkun chemical co., Ltd (Bengbu, China), the Na₃PO₄, NaH₂PO₄ and Na₂HPO₄ were purchased from Damao Chemical Reagent Factory (Tianjin, China). All reagents were of grade analytical and used without further purification.