Mr750 3.0t scanner

Manufactured by GE Healthcare

Sourced in United States

The MR750 3.0T scanner is a magnetic resonance imaging (MRI) system developed by GE Healthcare. The system is designed to generate high-quality, 3-dimensional images of the body's internal structures using a powerful 3.0 Tesla magnetic field.

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Lab products found in correlation

32 channel head coil, by GE Healthcare (2 mentions) 8 channel cranial coil, by GE Healthcare (1 mentions) 8 channel head coil, by GE Healthcare (1 mentions)

Spelling variants of this product

MR750 (286 citations) MR750 scanner (64 citations) Discovery MR750 3.0T scanner (45 citations) 3.0T scanner (23 citations) Discovery MR750 3.0T MRI scanner (9 citations) Discovery MR750 3.0T MR scanner (3 citations) Scanners (2 citations)

13 protocols using mr750 3.0t scanner

Resting-state fMRI and Anatomical Imaging in TIA Patients

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MR data was acquired using a GE MR-750 3.0 T scanner (GE Medical Systems, Inc., Waukesha, WI, United States) at Anshan Changda Hospital, China. The time interval between the last TIA attack and subsequent MRI scanning was 0.25–6 days for the patients. During the data acquisition, participants were instructed to keep awake, relax with their eyes closed and remain motionless as much as possible.
Resting-state fMRI (rs-fMRI) data was obtained using an echo-planar imaging sequence with following protocols: 43 axial slices, TR = 2000 ms, TE = 30 ms, flip angle = 60°, matrix = 64 × 64, in-plane resolution of 3.44 mm × 3.44 mm, thickness/gap = 3.2/0 mm, 240 contiguous EPI functional volumes, 8 min.
3D high resolution T1-weighted anatomical images were acquired using a 3D-MPRAGE sequence: 176 sagittal slice, TR = 8100 ms, TE = 3.1 ms, matrix = 256 × 256, voxel size: 1 mm × 1 mm × 1 mm, thickness/gap = 1/0 mm. This session lasted for about 5 min.
Three patients were excluded from further analysis due to incomplete coverage of the whole brain for rs-fMRI scan (2) or the lost of 3D T1 image (1).

Lv Y., Li L., Song Y., Han Y., Zhou C., Zhou D., Zhang F., Xue Q., Liu J., Zhao L., Zhang C, & Han X. (2019). The Local Brain Abnormalities in Patients With Transient Ischemic Attack: A Resting-State fMRI Study. Frontiers in Neuroscience, 13, 24.

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Rhesus Macaque Neurodevelopmental MRI Analysis

Cited 4 times

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This study was performed based on a public rhesus macaque neurodevelopment data set with 32 (Macaca mulatta) [1 (link)], in which each monkey has 4 to 5 longitudinal MRI scans during early postnatal stages, by using a GE MR 750 3.0T scanner. The number of subjects at each age is shown in Fig. 2. T1-weighted (T1w) MR images were acquired using parameters: TI/TR/T E = 450/8.684/3.652 ms, FOV=140 ×140 mm, flip angle = 12, acquisition matrix= 256 × 256, and voxel size= 0.55 × 0.55 × 0.8 mm³. T2-weighted (T2w) MR images were acquired using parameters: T R/T E = 2500/87 ms, flip angle = 90, acquisition matrix= 256 × 256, and voxel size = 0.6 × 0.6 × 0.6 mm³.
All T2w MR images were rigidly aligned onto the corresponding T1w MR images, and all images were resampled to 0.55 × 0.55 × 0.55 mm³. To handle the low tissue contrast problem appeared in early stage postnatal MRI scans, we applied our in-house developed tools for infant brain tissue segmentation and cortical surface reconstruction [5 (link), 6 (link), 7 (link)]. At each vertex on the reconstructed cortical surfaces, the cortical morphological features (e.g., cortical thickness, sulcal depth, average convexity and curvature) were computed. All cortical surfaces were then mapped onto a standard sphere to facilitate further atlas construction and analysis.

Wang F., Lian C., Xia J., Wu Z., Duan D., Wang L., Shen D, & Li G. (2018). CONSTRUCTION OF SPATIOTEMPORAL INFANT CORTICAL SURFACE ATLAS OF RHESUS MACAQUE. Proceedings. IEEE International Symposium on Biomedical Imaging, 2018, 704-707.

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Structural and Functional MRI Acquisition

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Magnetic resonance imaging data were acquired using a GE MR750 3.0T scanner with an 8-channel cranial coil at the MRI Research Center, Institute of Psychology, Chinese Academy of Sciences. T1-weighted anatomical images were acquired using a 3D-SPGR pulse sequence [192 sagittal slices, repetition time (TR) = 6.65 ms, echo time (TE) = 2.93 ms, flip angle (FA) = 12°, field of view (FOV) = 256 mm × 256 mm, matrix size = 256 × 256, slice thickness = 1 mm, voxel size = 1 × 1 × 1 mm³]. The functional data were acquired with echo-planar imaging (EPI) sequence (37 axial slices, TR = 2000 ms, TE = 30 ms, FA = 90 degrees, FOV = 224 mm × 224 mm, matrix size = 64 × 64, slice thickness = 3.5 mm, voxel size = 3.5 × 3.5 × 3.5 mm³).

Li H.X, & Hu X. (2022). Dialectical Thinking Is Linked With Smaller Left Nucleus Accumbens and Right Amygdala. Frontiers in Psychology, 13, 760489.

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High-Resolution fMRI Acquisition Protocol

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Images were acquired on a GE MR750 3.0T scanner. The anatomical images were scanned using a T1-weighted axial sequence parallel to the anterior-commissure-posterior commissure line. Each anatomical scan had 156 axial slices (spatial resolution = 1 mm × 1 mm × 1 mm, field of view = 256 mm × 256 mm, time repetition [TR] = 8.124 ms). The functional images were scanned using a T2^∗-weighted single-shot gradient EPI sequence with a TR of 2 s. Each functional volume contained 43 axial slices (spatial resolution = 3.75 mm × 3.75 mm × 3.3 mm, field of view = 240 mm × 240 mm, TE = 28 ms, flip angle = 90°). Each fMRI run lasted for 416 s (208 TRs). During image acquisition, software monitored head movement in real-time. When the head movement exceeded 3 mm or 3° within a run, the scanning for that run was re-started using a new trial sequence.

Wu X., Wang T., Liu C., Wu T., Jiang J., Zhou D, & Zhou J. (2017). Functions of Learning Rate in Adaptive Reward Learning. Frontiers in Human Neuroscience, 11, 592.

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Resting-state MRI of Transient Ischemic Attack

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MRI scans were performed using a GE MR-750 3.0 T scanner (GE Medical Systems Inc., Waukesha, WI, United States). For individuals with TIA, there was a time interval from the latest TIA to the subsequent MRI scan of 6 hours to 16 days. All participants were instructed to relax, stay still, keep their eyes closed but not fall asleep, and not to think systematically during resting-state scanning [15 (link)]. Functional MRI scans were acquired using an echo planar imaging sequence with repetition time (TR)/echo time (TE) = 2000 ms/30 ms, flip angle (FA) = 60°, acquisition matrix = 64 × 64, slice thickness = 3.2 mm, gap = 0 mm, and slices = 43. The scanning time for the functional MRI was 8 minutes (240 volumes). The structural MRI data were acquired using a high-resolution anatomic sagittal 3D T1 sequence (voxel size = 1 mm × 1 mm × 1 mm), TR/TE = 8100 ms/3.1 ms, 176 slice acquisition matrix = 256 × 256, slice thickness = 1 mm, and gap = 0 mm. The scanning time for the structural MRI was 5 minutes.

Hao Z., Song Y., Shi Y., Xi H., Zhang H., Zhao M., Yu J., Huang L, & Li H. (2022). Altered Effective Connectivity of the Primary Motor Cortex in Transient Ischemic Attack. Neural Plasticity, 2022, 2219993.

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Multi-Contrast 3T MRI Protocols for Hematoma and MS

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Five cerebral hematoma patients were scanned using a GE Signa HDxt 3 T scanner (GE Healthcare, Waukesha, WI) equipped with an 8-channel head coil. Phase images with whole-brain coverage were acquired using a standard flow-compensated 3D SPGR sequence with the following parameters: TE₁/ΔTE/TE₁₆ = 3.16/4.85/75.9 ms, TR = 43 ms, FA = 12°, FOV = 220×220×132 mm³, matrix size = 256×256×66. This protocol resulted in an isotropic in-plane resolution (0.86×0.86 mm²) with 2 mm slice thickness. Total acquisition time was about 12 minutes.
In vivo brain image data from 4 patients with multiple sclerosis were acquired on a GE MR750 3.0T scanner using the 3D SPGR sequence with the following parameters: TE₁/ΔTE/TE₁₆ = 3.00/4.18/65.7 ms, TR = 54 ms, FA = 12°, FOV = 220×220×132 mm³, matrix size = 256×256×132, spatial resolution = 0.86×0.86×1 mm³. All experiments were approved by the local institutional review boards. Total acquisition time was about 30 minutes.

Wei H., Dibb R., Zhou Y., Sun Y., Xu J., Wang N, & Liu C. (2015). Streaking Artifact Reduction for Quantitative Susceptibility Mapping of Sources with Large Dynamic Range. NMR in biomedicine, 28(10), 1294-1303.

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Quantifying Optic Radiation Lesions in MRI

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Annual brain MRI scans were acquired on a GE MR750 3.0-T scanner with an 8-channel head coil as previously described^{3 (link)} using pre- and post-contrast (gadolinium) sagittal 3D T1, axial fluid attenuated inversion recovery (GE CUBE T2 FLAIR), and whole brain 64-directions diffusion-weighted imaging sequences. Probabilistic tractography was used to reconstruct OR fibers. Individual lesions were identified on coregistered T2 FLAIR images and semiautomatically segmented using JIM 7 software (Xinapse Systems, Essex, United Kingdom). Lesions were then intersected with OR fibers to obtain OR lesion volume measures.

You Y., Barnett M.H., Yiannikas C., Parratt J.D., Matthews J.G., Graham S.L, & Klistorner A. (2021). Interferon-β Is Less Effective Than Other Drugs in Controlling the Rate of Retinal Ganglion Cell Loss in MS. Neurology® Neuroimmunology & Neuroinflammation, 8(3), e971.

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Resting-state fMRI Acquisition Protocol

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GE MR-750 3.0 T scanner (GE Medical Systems, Inc., Waukesha, WI, United States) was used. The time interval between the latest TIA attack and subsequent MRI scanning was 0.25–16 days for the patients. During the resting state scanning, all participants were instructed to refrain from any cognitive task (Biswal et al., 1995 (link)). Specifically, all participants were required to keep relaxed, to close their eyes but not fall asleep, not to think systematically, and to remain motionless.
BOLD-fMRI EPI (echo planar imaging) scan parameters included TE (echo time) = 30 ms, TR (repetition time) = 2,000 ms, FA (flip angle) = 60°, matrix size = 64 × 64, thickness/gap = 3.2/0 mm, slices = 43, time = 8 min. A total of 240 scans were collected.
The high-resolution anatomic 3D T1 sequence had the following parameters: 176 sagittal slice, TR = 8,100 ms, TE = 3.1 ms, matrix = 256 × 256, voxel size = 1 mm × 1 mm × 1 mm, thickness/gap = 1/0 mm. This session lasted for about 5 min.

Ma H., Huang G., Li M., Han Y., Sun J., Zhan L., Wang Q., Jia X., Han X., Li H., Song Y, & Lv Y. (2022). The Predictive Value of Dynamic Intrinsic Local Metrics in Transient Ischemic Attack. Frontiers in Aging Neuroscience, 13, 808094.

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High-Resolution Multimodal Brain Imaging

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Functional images were acquired at the Duke-UNC Brain Imaging and Analysis Center (BIAC) on a General Electric (Waukesha, WI, USA) MR750 3.0 T scanner equipped with 50 mT/m gradients (200 T/m/s slew rate) and an 8-channel head coil for parallel imaging. High resolution T1-weighted anatomical images were acquired with 162 axial slices using a FSPGR pulse sequence (TR = 7.584 ms; TE = 2.936 ms; FOV = 256 mm; image matrix = 256 × 256; voxel size = 1 × 1 × 1 mm; flip angle = 12°) and used for normalization and coregistration with the functional data. This structural image was aligned in a near axial plane defined by the anterior and posterior commissures. Whole-brain functional images were acquired using a spiral-in SENSE sequence (TR = 1500 ms; TE = 30 ms; FOV = 240 mm; image matrix, 64 × 64; flip angle = 60°; voxel size, 3.75 × 3.75 × 4.0 mm; 34 axial slices) to reduce susceptibility artifacts and recover signal in orbital frontal regions (Pruessmann et al., 2001 (link); Truong and Song, 2008 (link)). A semi-automated high-order shimming program ensured global field homogeneity.

Carl H., Walsh E., Eisenlohr-Moul T., Minkel J., Crowther A., Moore T., Gibbs D., Petty C., Bizzell J., Dichter G.S, & Smoski M.J. (2016). Sustained anterior cingulate cortex activation during reward processing predicts response to psychotherapy in major depressive disorder. Journal of affective disorders, 203, 204-212.

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Multimodal MRI Acquisition Protocol

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All participants will be scanned using an MR750 3.0T scanner (General Electric Company) at the Department of Radiology in Beijing Children’s Hospital. First, a three-dimensional magnetisation prepared rapid gradient echo sequence will be used to acquire T1-weighted images, and its parameters are listed: TR=2530 ms, TE=2.34 ms, TI=1100 ms, resolution=256×256, flip angle=7, slices=176 and slice thickness=1 mm. The T1 sequence lasted for 649 s. After T1-weighted image acquisition, all participants will also undergo T2-weighted image scans that lasted for 60 s to exclude incidental central nervous system diseases. We will acquire resting-state fMRI (rs-fMRI) scans by T2-weighted echo planar imaging with the following parameters: TR=2500 ms, TE=21 ms, slices=42, flip angle=90, slice thickness=35, field of view=200 mm, resolution=64×64, voxel size=3.1×3.1×3.5 mm and bandwidth=2520 Hz/Px.

Wang F., Wen F., Liu J., Yan J., Yu L., Li Y, & Cui Y. (2022). Classification of tic disorders based on functional MRI by machine learning: a study protocol. BMJ Open, 12(5), e047343.

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