Data acquisition and preprocessing were identical to those described in (49 (link)); details are available in the Supplement . Briefly, eight-minute rsfMRI scans (3.75×3.75×3.5mm resolution, 64×64 matrix, repetition time (TR) of 2.5s) were acquired on a 3T GE Healthcare MRI scanner (HDX; Milwaukee, WI) with an eight-channel coil. Participants were asked to close their eyes and relax but not fall asleep.
Eight channel coil
Manufactured by GE Healthcare
The eight-channel coil is a piece of lab equipment designed for magnetic resonance imaging (MRI) applications. It is an essential component that provides high-quality signal reception and enhances imaging capabilities. The device features eight independent channels that work together to capture detailed images, enabling healthcare professionals to make informed diagnoses and treatment decisions.
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Lab products found in correlation
Excite scanner, by GE Healthcare (3 mentions)
Ge signa hdxt scanner, by GE Healthcare (2 mentions)
3 tesla scanner, by GE Healthcare (1 mentions)
Signa whole body scanner, by GE Healthcare (1 mentions)
Eight channel phase array head coil, by GE Healthcare (1 mentions)
Signa hdxt scanner, by GE Healthcare (1 mentions)
11 protocols using eight channel coil
1
Resting-State fMRI Acquisition and Preprocessing
2
Multimodal Neuroimaging Protocol for DTI Analysis
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All MRI imaging data were acquired with a 3.0 Tesla GE Excite scanner using an eight-channel coil (GE Medical System, Milwaukee, WI), including a high-resolution T1-weighted image and diffusion tensor imaging (DTI) scans.
DTI sequences were obtained including 30 volume sequences with diffusion gradients applied along 30 non-collinear directions (b = 1000 s/mm2) and one volume sequence with a b value of 0 s/mm2, and the following parameters were slice thickness, 4 mm; field of view (FOV) = 240 × 240 mm2; matrix size = 128 × 128; repetition time (TR) = 40,000 ms; and echo time (TE) = 84 ms. Additionally, high-resolution anatomical images were also acquired by applying a T1-weighted three-dimensional MRI sequence with the following parameters: 140 axial slices; TR = 8.5 ms; TE = 3.4 ms; flip angle = 12°; slice thickness = 1.0 mm; no gap; matrix = 240 × 240; and FOV = 240 × 240 mm2. Each participant was placed in a standard head coil to decrease head movement during MRI data acquisition.
DTI sequences were obtained including 30 volume sequences with diffusion gradients applied along 30 non-collinear directions (b = 1000 s/mm2) and one volume sequence with a b value of 0 s/mm2, and the following parameters were slice thickness, 4 mm; field of view (FOV) = 240 × 240 mm2; matrix size = 128 × 128; repetition time (TR) = 40,000 ms; and echo time (TE) = 84 ms. Additionally, high-resolution anatomical images were also acquired by applying a T1-weighted three-dimensional MRI sequence with the following parameters: 140 axial slices; TR = 8.5 ms; TE = 3.4 ms; flip angle = 12°; slice thickness = 1.0 mm; no gap; matrix = 240 × 240; and FOV = 240 × 240 mm2. Each participant was placed in a standard head coil to decrease head movement during MRI data acquisition.
3
Resting-state fMRI Data Collection
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Data acquisition and preprocessing were identical to those described in [49 (link)]; details are available in the Supplementary. Briefly, eight-minute rsfMRI scans (3.75 × 3.75 × 3.5 mm resolution, 64 × 64 matrix, repetition time (TR) of 2.5 s) were acquired on a 3 T GE Healthcare MRI scanner (HDX; Milwaukee, WI) with an eight-channel coil. Participants were asked to close their eyes and relax but not fall asleep.
4
Diffusion MRI Protocol for White Matter Analysis
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Scanning was performed using a 3-Tesla scanner (GE Healthcare, Milwaukee) with an eight-channel coil, with 60 diffusion-weighted directions (B = 1000 s/mm2), eight opening B = 0 directions and a 2mm2 resolution (echo time = 81.6 ms, repetition time = 7600 ms). Images were pre-processed using the automatic quality-control feature of DTIPrep (Oguz et al., 2014 (link)) and were tensor-fitted using the FSL software package (Jenkinson et al., 2012 (link)), generating FA, axial and radial diffusivity maps (AD and RD). AD and RD metrics are thought to represent different aspects of white matter microstructure (axonal structure and myelination, respectively), while FA is a scalar measure of apparent coherence of fiber orientation, considered a proxy measure of microstructural architecture. See Supplementary material for details.
5
Diffusion Tensor Imaging Protocol for Brain Mapping
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All subjects were scanned on a 3.0 Tesla GE Excite scanner using an eight channel coil (GE Medical Systems, Milwaukee, WI). DTI images were obtained with a single-shot echo-planar imaging sequence where the diffusion sensitizing gradients were applied along two repeats of 30 non-collinear directions (b = 1000 s/mm2) with five repeats of the b0 (no diffusion weighted image). The imaging parameters were 75 continuous axial slices with a slice thickness of 2 mm and no gap, field of view (FOV) = 256*256 mm2; TR = 9400 ms; TE = 84 ms; and matrix size = 128 × 128, resulting in 2 mm isotropic voxels.
For each subject, a high-resolution structural image was acquired by using a three-dimensional MRI sequence with a voxel size of 1 × 1 × 1 mm3 using an axial Fast Spoiled Gradient Recalled sequence (FSGPR) with the following parameters: repetition time (TR) = 1.900 ms; echo time (TE) = 2.26 ms; data matrix = 256 × 256; and field of view (FOV) = 256 × 256 mm2.
For each subject, a high-resolution structural image was acquired by using a three-dimensional MRI sequence with a voxel size of 1 × 1 × 1 mm3 using an axial Fast Spoiled Gradient Recalled sequence (FSGPR) with the following parameters: repetition time (TR) = 1.900 ms; echo time (TE) = 2.26 ms; data matrix = 256 × 256; and field of view (FOV) = 256 × 256 mm2.
6
Resting-state fMRI of Ketamine Effects
7
High-Resolution 3T MRI Brain Imaging
8
Diffusion Tensor Imaging of the Brain
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All subjects were scanned on a 3.0 Tesla GE Excite scanner using an eight-channel coil (GE Medical Systems, Milwaukee, WI). DTI was obtained with a single-shot echo-planar imaging sequence. The diffusion sensitizing gradients were applied along two repeats of 30 non-collinear directions (b = 1,000 s/mm2) with five repeats of b0 (no diffusion weighted image). The imaging parameters were: 75 continuous axial slices with a slice thickness of 2 mm and no gap; field of view (FOV) = 256; TR = 9,400 ms; TE = 84 ms; and matrix size = 128 × 128, resulting in 2 mm isotropic voxels.
9
Diffusion-Weighted Imaging Protocol for Brain MRI
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For all participants, MRI data were acquired using a 3.0-T GE Signa HDxt scanner (GE Healthcare, Milwaukee, WI, USA) at CHA Bundang Medical Center. Diffusion-weighted images (DWI) were acquired using an echo planar imaging (EPI) sequence with the following parameters: repetition time, 17,000 ms; echo time, 108 ms; field of view, 240 mm; 144×144 matrix; slice thickness, 1.7 mm; and voxel size, 1.67× 1.67×1.7 mm3. A double-echo option was used to reduce the distortion effect of the eddy currents. An eight-channel coil and an array of spatial sensitivity encoding techniques (ASSET; GE Healthcare) with a sensitivity encoding (SENSE) factor of two were applied to reduce the effect of EPI spatial distortions. Seventy axial slices parallel to the anterior commissureposterior commissure line for the whole brain were acquired in fifty-one directions with a b-value of 900 s/mm2. Eight baseline scans at b=0 s/mm2 were also obtained. Using the leastsquares method, DTIs were extracted from DWIs (approximate scan time of 17 min).
10
Diffusion Tensor Imaging Protocol
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All participants underwent MRI using a 3.0-Tesla GE Signa HDxt scanner (GE Healthcare, Milwaukee, WI, USA) comprising an eight-channel phase-array head coil at CHA Bundang Medical Center. Diffusion-weighted images were acquired using an echo planar imaging (EPI) sequence with the following parameters: repetition time = 17,000 ms; echo time = 108 ms; field of view = 240 mm; matrix = 144 × 144; slice thickness = 1.7 mm; voxel size = 1.67 × 1.67 × 1.7 mm3. A double-echo option was applied to minimize eddy-current-related distortions. An eight-channel coil and Array of Spatial Sensitivity Encoding Technique (GE Healthcare) with a SENSE factor of 2 were used to reduce the impact of EPI spatial distortions. Seventy axial slices parallel to the anterior commissure–posterior commissure line covering the whole brain were acquired in 51 directions with a b-value of 900 s/mm2. Eight baseline scans with b = 0 s/mm2 were also acquired. DTIs were estimated from the diffusion-weighted images using the least-squares method. The total scanning time was 17 min.
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