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Cb6f1

Manufactured by Charles River Laboratories
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Sourced in Germany

The CB6F1 is a mouse model developed by Charles River Laboratories. It is a hybrid mouse strain that combines characteristics of the C57BL/6 and BALB/c mouse strains. The CB6F1 model is commonly used in a variety of research applications, including immunology, oncology, and drug development studies.

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Lab products found in correlation

C57bl 6, by Jackson ImmunoResearch (1 mentions) Nod scid il2rγ null mice, by Jackson ImmunoResearch (1 mentions) Female balb c, by Charles River Laboratories (1 mentions) C57bl 6 mice, by Charles River Laboratories (1 mentions)

Spelling variants of this product

CB6F1 mice (11 citations) Female CB6F1 mice (3 citations) CB6F1/Crl mice (2 citations)

3 protocols using cb6f1

1

Neuroprotective Nanoparticle Efficacy in Mice

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For animal studies, CD-1 (Charles River Labs), CB6F1 (Charles River Labs) and C57/BL6 (Jackson Labs) female mice with 20 g body weight were used. All animal work was approved and monitored by the University of North Carolina Animal Care and Use Committee.
Sample size is calculated based on our preliminary data with Wtmn and CPZ NPs. We calculated an effect size of 1.821. The nonparametric analog of this effect size can be stated in terms of p1=Pr (X1 is true. The null hypothesis being tested is p1=0.5. For effect size 1.821, p1=0.099. A sample size of 8 in each group will have 80% power to detect a probability of 0.099 that an observation in Group X is less than an observation in Group Y, using a Wilcoxon (Mann-Whitney) rank-sum test, with a 0.05 two-sided significance level.
Yang F., Medik Y., Li L., Tian X., Fu D., Brouwer K.L., Wagner K., Sun B., Sendi H., Mi Y, & Wang A.Z. (2020). Nanoparticle drug delivery can reduce the hepatotoxicity of therapeutic cargo. Small (Weinheim an der Bergstrasse, Germany), 16(7), e1906360.
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2

Mouse Strain Comparison for Research

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Age-matched 5-12 week-old female CAF1/J and NOD-scid IL2Rγnull mice were purchased from The Jackson Laboratory (Bar Harbor, ME), CB6F1 from Charles Rivers Laboratories (Wilmington, MA) and BALB/c from the National Cancer Institute (Frederick, MD). Mice were housed in specific pathogen-free conditions and cared for according to the guidelines of the University of Arizona Institutional Animal Care and Use Committee (IACUC).
Stokes J., Hoffman E.A., Zeng Y., Larmonier N, & Katsanis E. (2016). Post-transplant bendamustine reduces GvHD while preserving GvL in experimental haploidentical bone marrow transplantation. British journal of haematology, 174(1), 102-116.
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3

Murine Leukemia Virus Infection in Mice

Cited 1 time
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Female BALB/c, CB6F1, and C57BL/6 mice were purchased from Charles River (Erkrath, Germany). Fluorescently labelled FV containing mWasabi-modified Friend murine leukemia virus has been described before [6 (link)]. Different strains of mice were infected with different doses of mWasabi-FV in PBS (BALB/C with 500 SFFU, CB6F1 1500 SFFU, and C57BL/6 20 000 SFFU respectively) by intravenous injection of total volume of 100 μl.
Malyshkina A., Bayer W., Podschwadt P., Otto L., Karakoese Z., Sutter K., Bruderek K., Wang B., Lavender K.J., Santiago M.L., Leipe P.M., Elsner C., Esser S., Brandau S., Gunzer M, & Dittmer U. (2023). Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles. PLOS Pathogens, 19(10), e1011725.
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