Log In Sign up
The largest database of trusted experimental protocols

α muricholic acid

Manufactured by Steraloids
Visit Supplier
Sourced in Canada, United States

α-muricholic acid is a naturally occurring bile acid. It is a key component in the bile of certain animal species. This compound is commonly used in laboratory research settings for various scientific applications.

Automatically generated - may contain errors

Lab products found in correlation

β muricholic acid, by Steraloids (3 mentions) Glycodeoxycholic acid, by Steraloids (2 mentions) Chenodeoxycholic acid, by Steraloids (2 mentions) Deoxycholic acid, by Steraloids (2 mentions) Cholic acid, by Steraloids (2 mentions) Glycocholic acid, by Steraloids (2 mentions) Glycochenodeoxycholic acid, by Steraloids (2 mentions) Taurocholic acid, by Steraloids (2 mentions) Taurodeoxycholic acid, by Steraloids (2 mentions) Taurochenodeoxycholic acid, by Steraloids (2 mentions) Taurolithocholic acid, by Steraloids (2 mentions) Tauro β muricholic acid, by Steraloids (2 mentions) ω muricholic acid, by Steraloids (2 mentions) Fetal calf serum (fcs), by Merck Group (1 mentions) Dulbecco s modified eagle s medium, by Merck Group (1 mentions) Trisodium citrate, by Merck Group (1 mentions) N n dimethylformamide (dmf), by Merck Group (1 mentions) Lithocholic acid, by Steraloids (1 mentions) Ursodeoxycholic acid, by Steraloids (1 mentions) Clofibric acid, by Merck Group (1 mentions)

3 protocols using α muricholic acid

1

Synthesis and Characterization of Bile Acid Derivatives

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Deoxycholic acid (DCA), chenoDeoxycholic acid (CDCA), cholic acid (CA), α-muricholic acid, β-muricholic acid, glycoDeoxycholic acid (GDCA), glycochenoDeoxycholic acid (GCDCA), and glycocholic acid (GCA) were obtained from Steraloids, Inc. Bile acid structures are shown in fig. S1. Bile acid A (37 ), 5-cholanic acid-3α,4β,7α-triol (7)(38 (link)), and AMPP (39 (link)) were synthesized according to published procedures. N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), 4-(dimethylamino)pyridine (DMAP), diethylamine, N,N-dimethylformamide, trisodium citrate, sodium hydroxide (NaOH), chloroform, Dulbecco’s modified Eagle’s medium, fetal calf serum, and penicillin G and streptomycin sulfate were obtained from Sigma–Aldrich. HPLC solvents (methanol and acetonitrile) were HPLC grade and were purchased from EMD Chemicals. Milli-Q ultrapure water was prepared in-house with a Milli-Q Integral Water Purification System.
Jiang X., Sidhu R., Mydock L., Hsu F.F., Covey D.F., Scherrer D.E., Earley B., Gale S.E., Farhat N.Y., Porter F.D., Dietzen D.J., Orsini J.J., Berry-Kravis E., Zhang X., Reunert J., Marquardt T., Runz H., Giugliani R., Schaffer J.E, & Ory D.S. (2016). Development of a Bile Acid-Based Newborn Screen for Niemann-Pick C Disease. Science translational medicine, 8(337), 337ra63.
+ Open protocol
+ Expand
2

Bile Acid Compound Sourcing Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Taurocholic acid (TCA), tauro-β-muricholic acid (TMCA), tauromurideoxycholic acid (TMDCA), taurochenodeoxycholic acid (TCDCA), taurodeoxycholic acid (TDCA), taurolithocholic acid (TLCA), cholic acid (CA), α-muricholic acid (αMCA), β-muricholic acid (βMCA), ω-muricholic acid (ωMCA), murideoxycholic acid (MDCA), ursodeoxycholic acid (UDCA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), and lithocholic acid (LCA) were purchased from either Steraloids, Inc. (Newport, RI) or Sigma-Aldrich (St Louis, MO). Clofibric acid (CLOF) was purchased from Sigma-Aldrich Co. (St. Louis, MO). Chloroform, agarose, and ethidium bromide were purchased from AMRESCO Inc. (Solon, OH). RNA-Bee was purchased from TelTest Inc. (Friendswood, TX). All other chemicals, unless indicated, were purchased from Sigma-Aldrich Co. (St. Louis, MO).
Zhang Y., Lickteig A.J., Csanaky I.L, & Klaassen C.D. (2017). Activation of PPARα decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion. Toxicology and applied pharmacology, 338, 112-123.
+ Open protocol
+ Expand
3

Quantifying Bile Acid Profiles

Check if the same lab product or an alternative is used in the 5 most similar protocols
BA standards including cholic acid (CA), chenodeoxycholic acid (CDCA), deoxycholic acid (DCA), lithocholic acid (LCA), ursodeoxycholic acid (UDCA) and hyodeoxycholic acid (HDCA) were purchased from Sigma-Aldrich Chemicals Co (Steinheim, Germany). α-muricholic acid (α-MCA), β-muricholic acid (β-MCA), ω-muricholic acid (ω-MCA), tauro-cholic acid (T-CA), tauro-chenodeoxycholic acid (T-CDCA), tauro-deoxycholic acid (T-DCA), tauro-lithocholic acid (T-LCA), tauro-ursodeoxycholic acid (T-UDCA), tauro-α-muricholic acid (T-α-MCA), tauro- β-muricholic acid (T-β-MCA), glyco-cholic acid (G-CA), glyco-chenodeoxycholic acid (G-CDCA), glyco-deoxycholic acid (G-DCA), glyco-lithocholic acid (G-LCA), glyco-ursodeoxycholic acid (G-UDCA) and deuterated internal standards (IS) lithocholic acid-2,2,4,4-D4 (LCA-D4), deoxycholic acid-2,2,4,4-D4 (DCA-D4) and glycochenodeoxycholic acid-2,2,4,4-D4 (GCDCA-D4) were obtained from Steraloids, Inc. (Newport, RI, USA). Methanol HPLC grade was from Merck (Darmstadt, Germany). Ultra-pure reagent water was purified by a Milli-Q gradient system (Millipore, Bedford, MA, USA). Acetonitrile LC-MS grade was from VWR and formic acid LC-MS grade was purchased from Sigma Aldrich Chemicals Co.
Ghaffarzadegan T., Essén S., Verbrugghe P., Marungruang N., Hållenius F.F., Nyman M, & Sandahl M. (2019). Determination of free and conjugated bile acids in serum of Apoe(−/−) mice fed different lingonberry fractions by UHPLC-MS. Scientific Reports, 9, 3800.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!