Most of the statistical analyses were performed with the Sigma-Stat software version 3.1 (Systat Software Inc., US). The obtained data are presented as a median (first quartile; third quartile) or as a mean ± standard deviation. The normality of distribution was tested with a Shapiro-Wilk test, and the statistical difference between the groups was evaluated with one-way analysis of variance or with a Mann-Whitney rank-sum test. A p value of ≤0.05 was considered statistically significant. The correlation between the evaluated parameters was evaluated with Pearson's correlation coefficient. IS, PCRn, and UA data are normally distributed. The post hoc power of the study was performed with the post hoc power calculator-ClinCalc (www.https://clincalc.com/stats/Power.aspx) (see Table 2).
Sigmastat software version 3
Manufactured by Grafiti LLC
Sourced in United States, Germany
SigmaStat software version 3.5 is a statistical analysis tool. It provides functions for data analysis and presentation.
Automatically generated - may contain errors
Lab products found in correlation
21 protocols using sigmastat software version 3
1
Statistical Analysis of Research Findings
2
Concentration-Response Analysis of Pharmacological Inhibition
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Data obtained from the inhibitory effect of the compounds on phasic and tonic contractions underwent a concentration-response curve analysis, which was performed using Sigma Plot version 14.0 notebook software (Systat Software Inc., San Jose, CA, USA) to obtain the inhibitory concentration-50 (IC 50 ) values, a drug concentration that reaches 50% of the maximum inhibitory effect (potency), and the E max , a maximum inhibitory response produced by the highest concentration of the tested compound (efficacy). All the data are expressed as the means ± standard error of the mean (SEM) from the determinations for each concentration (n = 6). The differences in IC 50 and E max values of the drugs were determined by the one-way ANOVA followed by a Student-Newman-Keuls or a Bonferroni post hoc tests using Sigma Stat Software version 3.1 (Systat Software Inc., San Jose, CA, USA). In all cases, P < 0.05 was considered statistically significant.
3
Obstetric Outcomes Analysis
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
It was done using SigmaStat software version 3.1 (Systat Software, Inc., Point Richmond, CA, USA). Patients and obstetric data were collected and presented as the mean ± SD or median (range). The analysis was carried out using the unpaired Student's t-test for comparison of data between the two groups and with Chi-square tests for dichotomous data. P < 0.05 was considered statistically significant.
4
Statistical Analysis of Patient Data
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Statistical analysis was performed using SigmaStat software version 3.1 (Systat Software, Inc., Point Richmond, CA, USA). Patients' data were collected and presented as mean ± SD or median (interquartile range), as appreciate. The analysis was carried out using the unpaired student's t-test between the two groups and the Chi-square test for dichotomous data.
5
Uterine Contractility Inhibition Assay
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Data for the effect of the drugs of interest on spontaneous uterine contractions were subjected to a concentration-response column analysis performed using Sigma Plot version 10 software (Systat Software Inc., San Jose, CA, USA) in order to obtain values for inhibitory concentration 50 (IC50) (a drug concentration that produces 50% of the maximum inhibitory effect), and Emax, a maximum inhibitory response that can be produced by the highest concentration of the tested compound. Data are expressed as the means±SEM taken from determinations for each concentration (n=5). The IC50 and Emax differences among the compounds were determined by a one-way ANOVA test followed by a post-hoc Student-Newman-Keuls test using Sigma Stat software, version 3.1 (Systat Software Inc., San Jose, CA, USA). In all cases, p<0.05 was considered statistically significant.
6
Concentration-Response Curve Analysis of Drugs
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Data for the effect of drugs on phasic and tonic contractions underwent a concentration-response curve analysis, which was performed using Sigma Plot version 10 software (Systat Software Inc., San Jose, CA, USA) to obtain the inhibitory concentration-50 (IC50) values, a drug concentration that produces 50% of the maximum inhibitory effect (potency), and the Emax, a maximum inhibitory response that can be produced by the highest concentration of the tested compound (efficacy). Data are expressed as the means±SEM from determinations for each concentration (n=6). The differences in IC50 and Emax among the compounds were determined by one-way ANOVA followed by a post hoc Student-Newman-Keuls test using Sigma Stat software version 3.1 (Systat Software Inc., San Jose, CA, USA). In all cases, p<0.05 was considered statistically significant.
7
Quantifying Robot-Mediated Treatment Effects
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The overall effect of the robot-mediated treatment was quantified using two approaches.
In addition, we analyzed the NEEM metrics to assess the intra-session effect of the treatment, by comparing the initial and final cycles of each session. For each session, median values of the first and last 5 flexion/extension cycles were extracted. The median values of all the indices extracted from the initial and final cycles of each session (from Days 1 to 10) were computed. MET and ZTA data from all participants were thus grouped in four vectors, namely METInit Cycle, METFinal Cycle, ZTAInit Cycle, and ZTAFinal Cycle. A Wilcoxon signed-rank test was used for comparison of initial and final cycles values.
Statistical significance was set at p < 0.05. SigmaStat software (version 3.5) (Systat Software, San Jose, CA, USA) was used for statistical analysis.
In addition, we analyzed the NEEM metrics to assess the intra-session effect of the treatment, by comparing the initial and final cycles of each session. For each session, median values of the first and last 5 flexion/extension cycles were extracted. The median values of all the indices extracted from the initial and final cycles of each session (from Days 1 to 10) were computed. MET and ZTA data from all participants were thus grouped in four vectors, namely METInit Cycle, METFinal Cycle, ZTAInit Cycle, and ZTAFinal Cycle. A Wilcoxon signed-rank test was used for comparison of initial and final cycles values.
Statistical significance was set at p < 0.05. SigmaStat software (version 3.5) (Systat Software, San Jose, CA, USA) was used for statistical analysis.
8
Comparative Analysis of Antioxidant Profiles
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All data are presented as median (25 and 75 quartiles-interquartile range). The calculations were performed using SigmaStat software version 3.5 (Systat Software Inc., Erkrath, Germany) and MedCalc software version 18.10 (MedCalc Software bvba, Belgium). After the exclusion of normality using the Kolmogorov-Smirnov test, differences between the two groups were analyzed using the Mann-Whitney U test. Friedman rank sum test for multiple comparisons and a subsequent Dunn test were used for time-dependent changes within each group. A P value of less than 0.05 was regarded as statistically significant.
9
Statistical Analysis of Experimental Data
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The data values were expressed as mean±SD. One-way analysis of variance (ANOVA) with post hoc LSD test was performed using Sigma Stat software version 3.5 (Systat Software Inc., San Jose, CA, USA). A p-value of less than 0.05 was considered a statistically significant difference.
10
Statistical Analysis of Experimental Data
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All data are presented as median (quartiles) unless otherwise stated. The calculations were done using SigmaStat software version 3.5 (Systat Software Inc., Erkrath, Germany). After exclusion of normality using the Kolmogorov– Smirnov test, differences within each group and between the groups were analyzed with the Kruskal-Wallis rank sum test for multiple comparisons and a subsequent Dunn’s test. A p value of less than 0.05 was regarded as statistically significant.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!