Gn rb1

Manufactured by Yuanye Bio-Technology

Sourced in China

Gn-Rb1 is a laboratory instrument used for the quantitative analysis of Ginsenoside Rb1, a bioactive compound found in the roots of Panax plants. It utilizes a sensitive analytical technique to measure the concentration of Ginsenoside Rb1 in various samples with high accuracy and precision.

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Lab products found in correlation

Bcl2 associated x (bax), by Cell Signaling Technology (1 mentions) Histone h3, by Abcam (1 mentions) Gp91phox, by Abcam (1 mentions) Gapdh, by Cell Signaling Technology (1 mentions) Bcl 2, by Cell Signaling Technology (1 mentions) Keap1, by Abmart (1 mentions) Vdac1, by Abcam (1 mentions) Cleaved caspases 3, by Abcam (1 mentions) 3 nitrotyrosine, by Abcam (1 mentions) Dihydroethidium dhe, by Beyotime (1 mentions) Mitofusin 2, by Abcam (1 mentions)

2 protocols using gn rb1

Mitochondrial Dysfunction and Oxidative Stress

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Gn-Rb1 was purchased from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China). Antibodies against gp91^phox, SOD₂, 3-nitrotyrosine, 4 hydroxynonenal, DRP1, DRP1 (phospho S637), DRP1 (phospho S616), Mitofusin 2, OPA1, Fis1, Histone H3, caspases-3, cleaved caspases-3, and VDAC1 were obtained from Abcam (Cambridge, MA, USA). GAPDH, Bax, and Bcl-2 were obtained from Cell Signaling Technology (Beverly, MA, USA). Nrf2, keap1, NQO1, HO1, Ndufs1, Ndufv1, Ndufs6, Ndufs4, Ndufv2, and Ndufa12 were obtained from Abmart (Shanghai, China). Dihydroethidium (DHE) wasobtained from Beyotime (Jiangsu, China).

Chen L., Geng N., Chen T., Xiao Q., Zhang H., Huo H., Jiang L., Shao Q, & He B. (2023). Ginsenoside Rb1 Improves Post-Cardiac Arrest Myocardial Stunning and Cerebral Outcomes by Regulating the Keap1/Nrf2 Pathway. International Journal of Molecular Sciences, 24(5), 5059.

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Investigating Inflammatory Pathways with Biochemical Assays

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GnRb1 was attained from Shanghai Yuanye Bio-Technology Co., Ltd. (Shanghai, China). LPS from E. coli strain (O55:B5) was obtained from Sigma (St. Louis, MO, USA). The ELISA kits to determine MPO, pro- and anti-inflammatory cytokines were obtained from Nanjing Jiancheng Bioengineering Institute (Nanjing, China). ELISA kits NF-κB pathway (total and phospho IκBα and NF-κB p65) proteins and primary, and secondary antibodies were procured from Cell Signaling Technology (CST, Danvers, MA, USA).

Shaukat A., Shaukat I., Rajput S.A., Shukat R., Hanif S., Shaukat I., Zhang X., Chen C., Sun X., Ye T., Niu K., Yao Z., Shaukat S., Safdar M., Abdelrahman M., Riaz U., Zhao J., Gu X, & Yang L. (2021). Ginsenoside Rb1 Mitigates Escherichia coli Lipopolysaccharide-Induced Endometritis through TLR4-Mediated NF-κB Pathway. Molecules, 26(23), 7089.

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