Animals were anesthetized by isoflurane inhalant. Animals were placed in sternal recumbency in a 16-slice Multi-Detector Computed Tomography unit (GE BrightSpeed, General Electric Company, Milwaukee, WI). Pre-contrast scans of the thorax and abdomen were acquired. A dynamic perfusion CT study of the liver was performed by scanning repeatedly an area of the liver (4 contiguous locations of 5 mm) over 60 seconds at 80 kVp after injection of a bolus of 0.5 ml/kg of iodinated contrast material (iohexol 350mgI/ml) at 4ml/sec using a power injector (GE Nemoto Dual-Shot injector, Waukesha, WI) at a maximum pressure of 2067 kP. After the perfusion study, a post-contrast scan of the whole body was obtained after injection of another bolus of 1.7 ml/kg of the same contrast material using the same injector and injection parameters. Thoracic scans were obtained at a thickness of 1.25 mm/120kVp with a lung algorithm and abdominal scans at a thickness of 2.5 mm/120kVp with a detail algorithm. A separate non-irradiated group of 3 animals (age matched to the other experimental animals evaluated by CT angiography) were subjected to the same CT protocol.
Ge brightspeed
Manufactured by GE Healthcare
Sourced in United States
The GE Brightspeed is a computed tomography (CT) imaging system designed to provide efficient and high-quality diagnostic imaging. It is capable of generating detailed cross-sectional images of the body, which can be used to identify and evaluate various medical conditions.
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11 protocols using ge brightspeed
1
Perfusion CT Imaging of Liver
2
Lung CT Scan Protocol for Pulmonary Lesion Assessment
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Lung CT scans were performed using one of three scanners (128-slice Somatom Definition Edge, Siemens Healthcare; 64-slice Ingenuity, Philips Healthcare; 16-slice GE Brightspeed, GE Medical System) without contrast media injection, with the patient in supine position, during end-inspiration. Scanning parameters were: tube voltage 120 KV, automatic tube current modulation, collimation width 0.625 or 1.25 mm, acquisition slice thickness 2.5 mm, and interval 1.25 mm. Images were reconstructed with a high-resolution algorithm at slice thickness 1.0/1.25 mm. During CT reporting, each radiologist completed both the usual radiology report as well as a structured report, including the presence/absence of GGO and consolidations, and the extension of pulmonary lesions using a visual scoring system (0%, 1–19%, 20–39%, 40–59%, and ≥60% of parenchymal involvement) [25 (link)].
3
Retrospective Multicenter CT Imaging Analysis
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All CT images used in the study were acquired on one of five multi-detector CT scanners (Siemens Edge Plus: Siemens Healthineers; Erlangen, Germany, GE Revolution CT, GE Brightspeed: GE Healthcare Chicago, Illinois, USA) available at the University Hospital of Liège. As CT images were collected prospectively as part of standard care, no standardized scan protocol was available over the complete dataset. Two thoracic radiologists performed CT scan analysis (PC: 3 years of experience, CD: 6 years of experience).
4
COVID-19 CT Imaging Acquisition Protocol
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CT scans were performed using one of three scanners (128-slice Somatom Definition Edge, Siemens Healthineers; 64-slice Ingenuity, Philips Healthcare; 16-slice GE Brightspeed, GE Healthcare) without contrast media injection, with the patient in supine position, during end-inspiration. Scanning parameters were as follows: tube voltage 120 KV, automatic tube current modulation, collimation width 0.625 or 1.25 mm, acquisition slice thickness 2.5 mm, and interval 1.25 mm. Images were reconstructed with a high-resolution algorithm at slice thickness 1.0/1.25 mm. Patients wore face masks, and thorough decontamination of the room was performed after each patient.
5
COVID-19 Pulmonary Lesion Assessment on CT
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CT scans were performed using one of the three scanners (128-slice Somatom Definition Edge, Siemens Healthineers; 64-slice Ingenuity, Philips Healthcare; 16-slice GE Brightspeed, GE Healthcare) without contrast media injection, with the patient in the supine position, during end-inspiration. Scanning parameters were tube voltage 120 KV, automatic tube current modulation, collimation width 0.625 or 1.25 mm, acquisition slice thickness 2.5 mm and interval 1.25 mm. Images were reconstructed with a high-resolution algorithm at slice thickness 1.0/1.25 mm. From the verbal and structured CT reports, the extension of pulmonary lesions estimated by using a visual scoring system resulted in a percentage of total lung parenchyma which had any pathological changes likely due to COVID-19.
6
Non-contrast CT Scan Techniques
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CT scans were performed without contrast media injection, with one of the following scanners: 128-slice Somatom Definition Edge, Siemens Healthcare; 64-slice Ingenuity, Philips Healthcare; 16-slice GE Brightspeed, GE Medical Systems. Other details on CT acquisition technique have been previously reported [12 (link)].
7
Biomechanical Evaluation of Spinal Ligaments
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Eight fresh-frozen human cadaveric specimens of L1–5 were included. Specimens were prepared by cleaning surrounding soft tissue and muscle and preserving the discs and spinal ligaments (supraspinous, interspinous, facet capsules, posterior longitudinal ligament, anterior longitudinal ligament). The mean specimen age was 66.5±11.5 years. There were 7 male and 1 female specimens. The average body mass index was 31.1±7.32 kg/m2. All specimens were visually inspected to confirm no fracture, deformity, previous surgery, or severe spondylosis.
A computed tomography (CT) scan (GE Brightspeed, Boston, MA, USA) was performed on all specimens (120 kV, 20 mA, 0.62-mm resolution) to investigate the bone quality and produce measurements to plan optimal implant size. Nondestructive testing was performed for all the conditions in flexion/extension, lateral bending, and axial rotation.
A computed tomography (CT) scan (GE Brightspeed, Boston, MA, USA) was performed on all specimens (120 kV, 20 mA, 0.62-mm resolution) to investigate the bone quality and produce measurements to plan optimal implant size. Nondestructive testing was performed for all the conditions in flexion/extension, lateral bending, and axial rotation.
8
Bladder Cancer Brachytherapy Imaging Protocol
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Patients with an applicator underwent T2-weighted MR imaging, with a 3 mm slice thickness using a 1.5-Tesla MRI scanner (Philips Archiva, Philips Medical Systems B.V., Eindhoven, The Netherlands) and CT imaging with a 1.25 mm slice thickness (GE Brightspeed, GE Medical Systems, Milwaukee, WI, USA) for brachytherapy planning. All patients followed the bladder filling protocol with 50-100 ml saline before the MRI and CT scans. The images were exported to brachytherapy planning system (BrachyVision version 13.6, Varian Medical Systems, Palo Alto, CA, USA). All target volumes and OAR delineations were performed on both image modalities by a same radiation oncologist.
9
Chest CT Imaging Protocol for QCT
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Chest CTs were performed using a 16-slice multidetector scanner (GE BrightSpeed; GE Healthcare, Waukesha, WI, USA) without intravenous contrast. Images were obtained as a single acquisition during inspiration using the following parameters: power of 120 KVp, current of 60 mA, gantry rotation time of 0.5 s, pitch of 1.375, collimation of 20 mm, increments of 5 mm, and 1.25-mm-thick reconstructions. The effective radiation doses ranged from 0.8 to 1.3 mSv, and the dose-length product was 69 to 86 mGy·cm. The protocol of the QCT was followed according to the recommendations by Newell et al [20 (link)].
10
CT Imaging of Emergency Patients
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CT scans were performed using one of three different types of scanner present in the five hospitals with an ER (128-slice Somatom Definition Edge, Siemens Healthineers; 64-slice Ingenuity, Philips Healthcare; 16-slice GE BrightSpeed, GE Healthcare) without contrast media injection, with the patient in supine position, during end-inspiration. Scanning parameters were tube voltage 120 kV, automatic tube current modulation, collimation width 0.625 or 1.25 mm, acquisition slice thickness 2.5 mm, and interval 1.25 mm. Images were reconstructed with a high-resolution algorithm at slice thickness 1.0/1.25 mm.
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