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Innova 4100

Manufactured by GE Healthcare
Sourced in United States

The Innova 4100 is a medical imaging system designed for interventional radiology procedures. It provides high-quality fluoroscopic and digital imaging capabilities to support a range of minimally invasive medical procedures.

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13 protocols using innova 4100

1

Digital Subtraction Angiography IVC Occlusion

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A Innova-4100 (GE Healthcare®, Milwaukee, WI, USA) digital subtraction angiographic imaging system was used, and a 5F pigtail catheter was placed through the femoral or jugular vein to the edge of the IVC occlusion. Iobitridol (25−35 mL of 300 mg I/mL; Guerbet®, Roissy, France) was injected at a rate of 15−20 mL/s. When the patients presented with a complete IVC occlusion after injection through the femoral vein, a second injection was performed via jugular vein cannulation using a 5F single-curve catheter.
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2

Diagnostic DSA for Cerebral Vasospasm

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Diagnostic DSA was performed using a biplane system (Axiom Artis, Siemens, Erlangen, Germany or AlluraClarity, Philips Healthcare, Best, The Netherlands) or a monoplane system (Innova 4100; GE Healthcare, Waukesha, WI, USA). Iopromid (60–120 mL, containing 300 mg iodine per mL) was used as the contrast agent.
Every patient who underwent intra-arterial spasmolysis primarily received a diagnostic DSA to assess the severity of angiographic cerebral vasospasm. DSA was performed according to vascular regions with suspected cerebral vasospasm. A comparison of the diagnostic DSA and DSA on admission, if applicable, was performed. Therefore, not all segments were necessarily examined in every patient at every time point, especially not the vertebrobasilar region.
We regularly performed intra-arterial administration of spasmolytics over the entire study period, first using nimodipine, later using milrinone, or a combination of both. Nitro-glycerine and/or alprostadil were added as expanded access if the effect of the primarily given substances was insufficient.
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3

Diagnostic DSA for Vascular Imaging

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Diagnostic DSA was performed using a biplane system (Axiom Artis, Siemens, Erlangen, Germany and AlluraClarity, Philips Healthcare, Best, The Netherlands) or a monoplane system (Innova 4100; GE Healthcare, Waukesha, WI, USA). Iopromid (60–120 mL, containing 300 mg iodine per mL) was used as the contrast agent.
DSA was performed according to vascular regions with suspected CVS. Therefore, not all segments were necessarily examined in every patient, especially not the vertebrobasilar circulation.
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4

Percutaneous Coronary Intervention Protocol

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Aspirin (oral administration, 100 mg/day) and clopidogrel (oral administration, 75 mg/day) were given routinely before elective PCI for at least 3 days. For patients undergoing emergency PCI, aspirin (oral administration, 300 mg/day) and clopidogrel (oral administration, 450–600 mg) were given after PCI. All patients were operated by the same three experienced cardiologists. Prestenting balloon dilatation was performed in all patients. Sirolimus-eluting stents (Firebird, Shanghai MicroPort Medical, China) were implanted using a conventional routine technique. The diameters of the stents were identical to the diameters of the affected arteries. The stents were 3–5 mm longer than the lengths of the affected segments. If residual stenosis was <20% and the TIMI flow grade was grade 3, stent implantation was considered successful. After the procedure, patients received clopidogrel (75 mg/day) for at least 12 months and life-long aspirin (100 mg/day).
Standard CAG was conducted with the Judkins technique using a digital subtraction angiography machine (Innova 4100, GE Healthcare, Waukesha, Wisconsin, USA). Two experienced interventional cardiologists with uniform training reviewed the CAG images independently and in a blind manner. The quantitative analysis of the CAG images was conducted by a validated independent central laboratory.
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5

3D Laryngeal Scaffold Imaging

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Following termination, the operative site was carefully dissected and the entire larynx and a portion of the trachea were explanted and CT imaged (Innova 4100; GE Healthcare, Little Chalfont, U.K., http://www3.gehealthcare.com) to produce a 3D rendition of the entire larynx, with the specific aim to locate the implanted decellularized scaffold.
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6

Vertebral Height Restoration Measurement

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The surgical procedures were performed with C-arm digitalized x-ray system (Angiostar, Siemens, Germany; Innova 4100, GE, USA) at a 40-cm field of view and automatic adaptation of kV, mA, and time of exposure. The fluoroscopic spot radiographs were exported to a workstation (Advantage Windows 4.0; GE, USA). The radiographs were reviewed to measure the anterior and middle vertebral heights before and after the surgeries. Then, the restoration percentage of the anterior and middle vertebral heights was calculated as follows: [35 ]
Rp=(HaHb)Hb×100%
where Rp is the restoration percentage of the anterior or middle vertebral height after the surgery, Ha is the anterior or middle vertebral height after the surgery, Hb is the anterior or middle vertebral height before the surgery.
The wedge angles were measured as described in our previous report [12 (link)]. Briefly, the wedge angle was measured as the angle between the upper endplate and the lower endplate of the treated vertebral body in the standard lateral fluoroscopic spot radiographs before and after the surgeries.
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7

Integrated Angiography-CT Imaging Protocols

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We analyzed the procedures performed in 3 different integrated ACT rooms. Two of them were equipped with an Innova 4100 angiography unit combined with a LightSpeed CT (ACT/SmartGantry Option LS system, GE Healthcare), and one was equipped with an IGS 540 combined with a Discovery RT wide bore CT (INTERACT Discovery RT, GE Healthcare). The angiography table was shared with the CT unit, which was mounted on a rolling platform, and as opposed to in conventional CT systems, the gantry was moving instead of the table during a CT scan. The ACT system had a user interface that allowed users to quickly switch the system into either imaging modality mode, and each system was equipped with a dedicated CT fluoroscopy kit.
In order to maximize patient access and scan range, the table was usually fully extended during CT scans, and more specifically during CT-guided procedures, though there was no specific requirement regarding the table’s longitudinal position to perform a CT acquisition. The ACT system allowed users to acquire multiple CT scans using a single scout image even if the user had changed the active modality from CT to fluoroscopy during the case.
Ultrasound devices used during the procedures were both the Logiq E9 or Logic S7 (GE Healthcare) systems.
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8

Dyna-CT Imaging of Liver Metastases

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A GE dyna-CT protocol was used for the study after calibration of a C-arm of Innova 4100 (GE) in anterior-posterior and lateral position. The region of interest dyna- CT acquisition was focused on the patients’ liver. The examination parameters were as follows: rotation angle of C-arm: 20°/s, rate of images capture: 15 fr/s, total time: 27s.
Only clearly separated metastatic tumours were measured in dyna-CT liver images during three TACE procedures (initial treatment, last treatment). RECIST criteria were used for treatment result assessment.
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9

Diagnostic DSA for Cerebral Vasospasm

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Diagnostic DSA was performed using a biplane system (Axiom Artis, Siemens, Erlangen, Germany or AlluraClarity, Philips Healthcare, Best, The Netherlands) or a monoplane system (Innova 4100; GE Healthcare, Waukesha, WI, USA). Iopromid (60–120 mL, containing 300 mg iodine per mL) was used as the contrast agent.
Every patient who underwent intra-arterial spasmolysis obtained a diagnostic DSA run to assess the severity of angiographic cerebral vasospasm. DSA was performed according to vascular regions with suspected cerebral vasospasm. A visual comparison of the diagnostic DSA and DSA on admission, if applicable, was performed. Therefore, not all segments were necessarily examined in every patient at every time point, especially not the vertebrobasilar circulation.
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10

Diagnostic Digital Subtraction Angiography

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Diagnostic digital subtraction angiography (DSA) was performed by neuroradiologists using either a biplane Siemens system (Axiom Artis, Erlangen, Germany) or a monoplane GE system (Innova 4100; GE Healthcare, Waukesha, Wisc). Iopromid (60–120 ml, containing 300 mg iodine per ml) was used as the contrast agent. For catheter placement, a femoral artery approach was employed in which the tip of a 4-F or 5-F catheter (Tempo® Catheter, Cordis, Miami, FL) was guided from the right or left common femoral artery to the ascending aorta and positioned in the right and left common carotid arteries. After the selective catheterization, at least three different views (posteroanterior, lateral and 45° oblique) were obtained for all patients. Quantification of ICA stenosis was measured according to the NASCET criteria [1 (link)].
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