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V plex vascular injury panel 2

Manufactured by MSD
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The V-plex vascular injury panel 2 is a multiplex assay that allows for the simultaneous quantitative measurement of multiple biomarkers associated with vascular injury. This panel provides a comprehensive assessment of various factors related to vascular health and function.

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Lab products found in correlation

V plex proinflammatory panel 1 human kit, by MSD (1 mentions) V plex proinflammatory panel 1, by Mesoscale (1 mentions)

2 protocols using v plex vascular injury panel 2

1

Multiparametric Cytokine Profiling by MSD

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Serum cytokines IL-1β, IL1Ra, IL-6, IL-8, IL-10, IL-18, CXCL10, ICAM, G-CSF, GM-CSF, TNFα, IFNg were quantified by MSD using the S-plex GM-CSF Human kit (MSD; K151F3S-1), the V-plex Cytokine panel 2 (human) kit (MSD; K151WTD), the V-plex Proinflammatory panel 1 (human) kit (MSD; K15049D), U-plex Human IL-18 (MSD; K151VJK), U-plex Human G-CSF (MSD; K151VGK), V-plex Chemokine panel 1 (human) kit (MSD; K151NVD), V-plex vascular injury panel 2 (human) kit (MSD; K151SUD) according to manufacturer’s protocol, with data acquired on a MESO QuickPlex SQ 120.
Bosteels C., Van Damme K.F., De Leeuw E., Declercq J., Maes B., Bosteels V., Hoste L., Naesens L., Debeuf N., Deckers J., Cole B., Pardons M., Weiskopf D., Sette A., Weygaerde Y.V., Malfait T., Vandecasteele S.J., Demedts I.K., Slabbynck H., Allard S., Depuydt P., Van Braeckel E., De Clercq J., Martens L., Dupont S., Seurinck R., Vandamme N., Haerynck F., Roychowdhury D.F., Vandekerckhove L., Guilliams M., Tavernier S.J, & Lambrecht B.N. (2022). Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment. Cell Reports Medicine, 3(12), 100833.
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2

Multiplex Biomarker Profiling Protocol

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Plasma concentrations of IFN-γ, TNF-α, interleukin-1-beta (IL-1-β), IL-2, IL-4, IL-6, IL-8, IL-10, IL-13, CRP, soluble intracellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) were measured using the multiplex V-Plex Pro-Inflammatory Panel 1 (Meso Scale Diagnostics (MSD; Maryland, USA), K15049D) and V-Plex Vascular Injury Panel 2 (MSD, K15198D) according to manufacturer’s instructions. Standards and samples were run in duplicate and the mean value for each duplicate pair was used in analyses. The lower limits of detection for each marker can be found in Supplementary Table 1.
Byrne J.F., Healy C., Mongan D., Susai S.R., Zammit S., Fӧcking M., Cannon M, & Cotter D.R. (2022). Transdiagnostic inflammatory subgroups among psychiatric disorders and their relevance to role functioning: a nested case-control study of the ALSPAC cohort. Translational Psychiatry, 12, 377.
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