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Flavine adenine dinucleotide

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Flavine adenine dinucleotide is a cofactor that plays a key role in various enzymatic reactions. It is a compound consisting of an adenine nucleotide and a flavin mononucleotide. Flavine adenine dinucleotide serves as a coenzyme for numerous oxidoreductase enzymes, facilitating the transfer of hydrogen or electrons during metabolic processes.

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Lab products found in correlation

Sodium tungstate, by Merck Group (2 mentions) Reduced nicotinamide adenine dinucleotide phosphate, by Merck Group (2 mentions) 2 6 dichlorophenolindophenol, by Merck Group (2 mentions) Glycylglycine, by Merck Group (2 mentions) Glutathione reductase, by Merck Group (2 mentions) 1 chloro 2 4 dinitrobenzene, by Merck Group (2 mentions) Oxidized glutathione, by Merck Group (2 mentions) 1 2 dithio bis nitro benzoic acid, by Merck Group (2 mentions) Tween 20, by Merck Group (2 mentions) Sodium hydroxide (naoh), by Merck Group (2 mentions) Bovine serum albumin (bsa), by Merck Group (2 mentions) Picric acid, by Merck Group (2 mentions) Glucose 6 phosphate (g6p), by Merck Group (2 mentions) Perchloric acid, by Merck Group (2 mentions) Reduced glutathione, by Merck Group (2 mentions) γ glutamyl p nitroanilide, by Merck Group (1 mentions) Trichloroacetic acid, by Merck Group (1 mentions) Thiobarbituric acid, by Merck Group (1 mentions) Nicotinamide adenine dinucleotide, by Roche (1 mentions) Nicotinamide adenine dinucleotide phosphate, by Merck Group (1 mentions)

3 protocols using flavine adenine dinucleotide

1

Glutathione Metabolism Assessment Methods

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Reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione reductase, γ-glutamylp-nitroanilide, glycylglycine, bovine serum albumin (BSA), 1,2-dithio-bis nitro benzoic acid (DTNB), 1-chloro-2,4-dinitrobenzene (CDNB), reduced nicotinamide adenine dinucleotide phosphate (NADPH), flavine adenine dinucleotide (FAD), glucose-6-phosphate, Tween-20, 2,6-dichlorophenolindophenol, thiobarbituric acid (TBA), picric acid, sodium tungstate, sodium hydroxide, trichloroacetic acid (TCA) and perchloric acid (PCA) were purchased from Sigma Chemicals Co. St. Louis, USA.
Shah N.A., Khan M.R, & Nigussie D. (2017). Phytochemical investigation and nephroprotective potential of Sida cordata in rat. BMC Complementary and Alternative Medicine, 17, 388.
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2

Metabolomic Standards for SAM and SAH

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S-(5′-Adenosyl)-l-methionine chloride dihydrochloride (A7007), crystalline S-(5′-Adenosyl)-l-homocysteine (A9384), Nicotinamide Adenine Dinucleotide Phosphate (N5755), Acetyl-Coenzyme A (A2056), Coenzyme A (C4812) and Flavine Adenine Dinucleotide (F6625) were obtained from Sigma-Aldrich. Nicotinamide Adenine Dinucleotide (10127964001) was from Roche Basel, Switzerland. The metabolomics standard SAMd3 (D-4093) was bought from CDN Isotopes Pointe-Claire, Canada, SAHd4 was from Cayman Chemical (9000372); tritiated SAM-[methyl-2H] at 250 μCi (NET155V250UC) was from PerkinElmer Waltham, US. Pierce™ Trypsin, MS-grade (90059) was from ThermoFisher Scientific Waltham, US.
Rosenberger F.A., Tang J.X., Sergeant K., Moedas M.F., Zierz C.M., Moore D., Smith C., Lewis D., Guha N., Hopton S., Falkous G., Lam A., Pyle A., Poulton J., Gorman G.S., Taylor R.W., Freyer C, & Wredenberg A. (2022). Pathogenic SLC25A26 variants impair SAH transport activity causing mitochondrial disease. Human Molecular Genetics, 31(12), 2049-2062.
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3

Glutathione Assay Protocol

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Reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione reductase, gamma-glutamyl p-nitroanilide, glycylglycine, bovine serum albumin (BSA), 1,2-dithio-bis nitro benzoic acid (DTNB), 1-chloro-2,4-dinitrobenzene (CDNB), reduced nicotinamide adenine dinucleotide phosphate (NADPH), CCl4, flavine adenine dinucleotide (FAD), glucose-6-phosphate, Tween-20, 2,6-dichlorophenolindophenol, thiobarbituric acid (TBA), picric acid, sodium tungstate, sodium hydroxide, trichloroacetic acid (TCA) and perchloric acid (PCA) were purchased from Sigma Chemicals Co. USA.
Alkreathy H.M., Khan R.A., Khan M.R, & Sahreen S. (2014). CCl4 induced genotoxicity and DNA oxidative damages in rats: hepatoprotective effect of Sonchus arvensis. BMC Complementary and Alternative Medicine, 14, 452.
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