1 3 dicyclohexylcarbodiimide

Manufactured by Merck Group

1,3-dicyclohexylcarbodiimide is a chemical compound commonly used as a coupling agent in organic synthesis. It is a versatile reagent that facilitates the formation of amide bonds between carboxylic acids and amines.

Automatically generated - may contain errors

Lab products found in correlation

Close spelling variants of this product

Dicyclohexylcarbodiimide (75 citations) 1,3-dicyclohexylcarbodiimide (DCC), (2 citations)

3 protocols using 1 3 dicyclohexylcarbodiimide

Synthesis and Characterization of TPGS Nanoparticles

Check if the same lab product or an alternative is used in the 5 most similar protocols

TPNa, d-α-tocopherol poly(ethylene
glycol) 1000 succinate (TPGS), PF127, 1,3-dicyclohexylcarbodiimide
(DCC), 2,6-di-tert-butyl-p-cresol
(BHT), and methanol were purchased from Sigma-Aldrich (St. Louis,
MO). MnTMPyP was from Calbiochem (EMD Millipore, Billerica, MA). 6-Maleimidohexanoic
acid was from AK Scientific (Union City, CA). Succinimidyl 4-[N-maleimidiomethyl]cyclohexane-1-carboxylate (SMCC) and N-succinimidyl S-acetylthioacetate (SATA)
were from Thermo Scientific Pierce (Rockford, IL). Streptavidin was
from Calbiochem (San Diego, CA). Mouse anti-PECAM MEC13.3 was purchased
from BD Bioscience (San Jose, CA), and monoclonal antibody (mAb 62)
against human anti-PECAM was provided by Dr. Marian Nakada (Centoor;
Malvern, PA). Whole molecule rat IgG was from Rockland Immunochemicals
(Gilbertsville, PA).

Howard M.D., Hood E.D., Greineder C.F., Alferiev I.S., Chorny M, & Muzykantov V. (2014). Targeting to Endothelial Cells Augments the Protective Effect of Novel Dual Bioactive Antioxidant/Anti-Inflammatory Nanoparticles. Molecular Pharmaceutics, 11(7), 2262-2270.

+ Open protocol

+ Expand

Synthesis and Characterization of Substituted Anilines

Check if the same lab product or an alternative is used in the 5 most similar protocols

The analytical grades of ethyl 4-aminobenzoate, sodium nitrite (NaNO₂), phenol, 1-bromohexane, 1,3-dicyclohexylcarbodiimide (DCC), 4-(N,N-dimethyl amino)pyridine (DMAP), 4-fluoro aniline, 2-fluoro aniline, 2-nitro aniline, 2-trifluoromethyl aniline, 2,4-dinitro aniline, potassium carbonate (K₂CO₃), sodium hydroxide (NaOH), potassium hydroxide (KOH), potassium iodide (KI) were procured from Sigma Aldrich and Spectrochem. For column chromatography silica gel 60-120 and neutral alumina were procured from Thomas baker. Acetone, hexane, ethyl acetate and dichloromethane were dried over phosphorus pentaoxide and calcium hydride, respectively. These solvents were distilled using standard methods when required for the experiment. Thin-layer chromatography (TLC) were performed on aluminium sheet precoated with silica gel-60 F₂₅₄ (Merck). Infrared (IR) spectra were recorded using a PerkinElmer 1000 spectrometer. Proton nuclear magnetic resonance (¹H NMR) spectra were recorded on a 400 MHz Bruker NMR spectrometer, using CDCl₃ as a solvent and tetramethyl silane (TMS) as an internal standard.

Sunil B.N., Behera P.K., Achalkumar A.S., Shanker G, & Hegde G. (2020). Influence of inter- and intramolecular H-bonding on the mesomorphic and photoswitching behaviour of (E)-4-((4-(hexyloxy)phenyl)diazenyl)-N-phenyl benzamides. RSC Advances, 10(34), 20222-20230.

+ Open protocol

+ Expand

Synthesis and Characterization of Functionalized Pluronic Hydrogels

Check if the same lab product or an alternative is used in the 5 most similar protocols

Pluronic F127® (Average Mw= 12600), acryloyl chloride, 4-dimethyl-aminopyridine (DMAP), 2,2-bis(hydroxymethyl)propionic acid (bis-MPA), acryloyl chloride, triethylamine (TEA), 1,3-dicyclohexylcarbodiimide (DCC), benzaldehyde dimethyl acetal, p-toluensulfonic acid monohydrate, 2-hydroxy-1-(4-(hydroxyethoxy) phenyl)-2methyl-1-propanone (Irgacure 2959, I2959), rhodamine B, CuSO 4 .5H 2 O, (L)-ascorbate and camptothecin were obtained from Sigma-Aldrich. Pluronic F127® was dried during 3 hours at 100 ⁰C under vacuum prior to use. All solvents were purchased from Sigma-Aldrich. 4-(dimethylamino) pyridinium 4-toluenesulfonate (DPTS), 6-azido-hexan-1ol, 2-(but-3-ynoyl)-2-methylpropane-1,3-diyl distearate (HCC-2C 18 ) [11] and tris(benzyltriazolylmethyl)amine [20] (TBTA) were synthesized according to previous reported procedures.

Jiménez-Pardo I., González-Pastor R., Lancelot A., Claveria-Gimeno R., Velázquez-Campoy A., Abian O., Ros M.B, & Sierra T. (2015). Shell Cross-Linked Polymeric Micelles as Camptothecin Nanocarriers for Anti-HCV Therapy. Macromolecular bioscience, 15(10).

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!