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Dspe peg 2kda mal

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DSPE-PEG(2kDa)-MAL is a heterobifunctional lipid-PEG conjugate with a maleimide functional group. It is designed for the conjugation of thiol-containing biomolecules to the distal end of the PEG chain.

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Lab products found in correlation

1 2 distearoyl sn glycero 3 phosphocholine, by Avanti Polar Lipids (1 mentions) Heparin, by Merck Group (1 mentions) Gwiz luc, by Aldevron (1 mentions) Sodium nitrite, by Merck Group (1 mentions) Gwiz gfp, by Aldevron (1 mentions) 3 5 dinitrosalicylic acid, by Merck Group (1 mentions) Triton x 100, by Merck Group (1 mentions) 5 5 dithiobis 2 nitrobenzoic acid, by Merck Group (1 mentions)

2 protocols using dspe peg 2kda mal

1

Lipid Modification and Crosslinking

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Lipids including 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-mPEG(2kDa)) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N [maleimide (polyethylene glycol)-2000] (ammonium salt) (DSPE-PEG(2kDa)-MAL) were obtained from Avanti Polar Lipids and used without further purification. Hetero-bifunctional cross-linker N-Succinimidyl 3-[2-pyridyldithio]-propionate (SPDP) was obtained from Pierce.
Chertok B, & Langer R. (2018). Circulating Magnetic Microbubbles for Localized Real-Time Control of Drug Delivery by Ultrasonography-Guided Magnetic Targeting and Ultrasound. Theranostics, 8(2), 341-357.
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2

Lipid-based Nanoparticle Formulation and Characterization

Check if the same lab product or an alternative is used in the 5 most similar protocols
Lipids including 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-mPEG(2 kDa)), 1,2-distearoyl-sn-glycero-3-phosphoethanol-amine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt) (DSPE-PEG(2 kDa)-MAL) and 1,2-dioleoyl-3-trimethy-lammonium-propane (DOTAP) were obtained from Avanti Polar Lipids and used without further purification. Heterobifunctional cross-linker 3-(2-pyridyldithio)propionyl hydrazide) (PDPH) was obtained from Pierce. Heparin, sodium nitrite, 3,5-dinitrosalicylic acid, tris(bipyridine)ruthenium(II) chloride), 5,5′-dithiobis(2-nitrobenzoic acid) (Ellman's reagent), tris(2-carboxyethyl)phosphine hydrochloride (TCEP-HCl), and Triton X-100 were obtained from Sigma-Aldrich and used without further purification. Plasmid DNA encoding for reporter proteins firefly luciferase (gWiz-Luc) and GFP (gWiz-GFP) were obtained from Aldevron.
Chertok B., Langer R, & Anderson D.G. (2016). Spatial Control of Gene Expression by Nanocarriers Using Heparin Masking and Ultrasound-Targeted Microbubble Destruction. ACS nano, 10(8), 7267-7278.
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