Spss for mac ver 20

All data were expressed as mean ± SD for four independent experimental groups. Statistical analysis was performed using SPSS for Mac Ver. 20.0 (SPSS, Inc., Chicago, IL, United States). All graphs were made using the Prism program (GraphPad, San Diego, CA, United States). The significance (P < 0.05) among different groups was evaluated using one-way ANOVA followed by the Tukey test.

Data were presented as mean ± (or median with interquartile range) for continuous variables that were normally (or not normally) distributed and as frequencies for categorical variables. The normal distribution of continuous parameters was analyzed by the Shapiro-Wilk test. After log transformation, the baseline GH concentration, IGF-1 index, and tumor volume were normally distributed. Student's t-test was used to analyze 2 groups of normally distributed continuous variables before or after log transformation. The significance of the differences in mean values among different groups was evaluated using one-way ANOVA followed by the Tukey test. To analyze the correlations between the IRS and clinical parameters, the Pearson correlation coefficient or the Spearman rank correlation coefficient was calculated when variables were normally or not normally distributed, respectively. Following this, parametric or nonparametric significance testing was performed. Statistical analyses were performed using the statistical package SPSS for Mac Ver. 20.0 (SPSS Inc., Chicago, IL, USA). P values less than 0.05 were considered to be statistically significant.

All statistical analyses were performed using SPSS for Mac Ver. 20.0 (SPSS Inc., Chicago, IL, USA). Data are expressed as mean ± SEM. The significance among different groups was evaluated using one-way ANOVA followed by the Tukey test. All graphs were made using PRISM program (GraphPad, San Diego, California, USA). Differences were considered statistically significant for P values <0.05.