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Human il 18

Manufactured by Abcam
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Human IL-18 is a recombinant protein that represents the mature form of human interleukin-18. Interleukin-18 is a proinflammatory cytokine that plays a role in the regulation of the immune response.

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Lab products found in correlation

Human cxcl10, by Abcam (2 mentions) Human il 1ra, by Abcam (2 mentions) Human gasdermin d, by MyBioSource (2 mentions) Cytometric bead array for human il 1b, by BD (2 mentions) Human anti spike rbd igg, by BioLegend (2 mentions) Human il 1β, by BD (2 mentions)

Spelling variants of this product

IL-18 (87 citations) Human IL-18 ELISA Kit (9 citations) Human IL-18 SimpleStep ELISA® Kit (2 citations)

2 protocols using human il 18

1

Quantifying Immune Responses to SARS-CoV-2

Check if the same lab product or an alternative is used in the 5 most similar protocols
Human IL-18 (Sigma or RND), human CXCL10 (RND), human IL-1RA(Abcam), Human Gasdermin D (MyBioSource) were quantified from supernatants of BMDMs infected (or not) with SARS-CoV-2-mNG or from serum or lung homogenates of SARS-CoV-2-mNG infected (or not) MISTRG6 or MISTRG6-hACE2 mice following manufacturer’s instructions. Human IL-1β was quantified from supernatants of BMDMs infected with SARS-CoV-2-mNG using cytometric bead array for human IL-1B (BD) following manufacturer’s instructions. Human anti-Spike-RBD IgG (Biolegend) was quantified from sera and lung homogenates of infected or uninfected MISTRG6-hACE2 mice.
Sefik E., Qu R., Junqueira C., Kaffe E., Mirza H., Zhao J., Brewer J.R., Han A., Steach H.R., Israelow B., Blackburn H.N., Velazquez S.E., Chen Y.G., Halene S., Iwasaki A., Meffre E., Nussenzweig M., Lieberman J., Wilen C.B., Kluger Y, & Flavell R.A. (2022). Inflammasome activation in infected macrophages drives COVID-19 pathology. Nature, 606(7914), 585-593.
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2

Quantifying Immune Responses to SARS-CoV-2

Check if the same lab product or an alternative is used in the 5 most similar protocols
Human IL-18 (Sigma or RND), human CXCL10 (RND), human IL-1RA(Abcam), Human Gasdermin D (MyBioSource) were quantified from supernatants of BMDMs infected (or not) with SARS-CoV-2-mNG or from serum or lung homogenates of SARS-CoV-2-mNG infected (or not) MISTRG6 or MISTRG6-hACE2 mice following manufacturer’s instructions. Human IL-1β was quantified from supernatants of BMDMs infected with SARS-CoV-2-mNG using cytometric bead array for human IL-1B (BD) following manufacturer’s instructions. Human anti-Spike-RBD IgG (Biolegend) was quantified from sera and lung homogenates of infected or uninfected MISTRG6-hACE2 mice.
Sefik E., Qu R., Junqueira C., Kaffe E., Mirza H., Zhao J., Brewer J.R., Han A., Steach H.R., Israelow B., Blackburn H.N., Velazquez S.E., Chen Y.G., Halene S., Iwasaki A., Meffre E., Nussenzweig M., Lieberman J., Wilen C.B., Kluger Y, & Flavell R.A. (2022). Inflammasome activation in infected macrophages drives COVID-19 pathology. Nature, 606(7914), 585-593.
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