Gamma med plus ix

Manufactured by Agilent Technologies

Sourced in United States

The Gamma-med Plus iX is a laboratory equipment product from Agilent Technologies. It is designed to measure and analyze gamma radiation. The core function of this product is to provide accurate and reliable gamma radiation detection and quantification for research and diagnostic applications.

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Lab products found in correlation

Brachyvision, by Agilent Technologies (1 mentions) Eclipse treatment planning system, by Agilent Technologies (1 mentions)

3 protocols using gamma med plus ix

Brachytherapy for Cancer Patients

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All patients were treated with a Gamma-med Plus iX (Varian medical systems, Palo Alto, CA) remote after a loader with an Ir 192 source. Subsequent applications were done similarly after 3–7 days. Patients did not undergo CT simulation for the remaining fractions, and the same plan was executed.
After completion of brachytherapy, patients were followed up every 2 months for 2 years, every 3 months for the third year and 6 months thereafter and annually after 5 years. They underwent a clinical examination only at each follow-up. Imaging was reserved for symptomatic patients or patients with suspected recurrence. All recurrences were proven by biopsy. Treatment failures were classified as local recurrence, loco-regional recurrence or distant metastases.

Rishi K.S., David S., Pathikonda M., Ramachandra P., Giri G.V., Vadaparty A, & Srinath B.S. (2021). Preliminary clinical outcomes of patients treated with vaginal brachytherapy alone using multi-channel vaginal brachytherapy applicator in operated early-stage endometrial cancer. Reports of Practical Oncology and Radiotherapy, 26(1), 43-49.

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HDR Surface Mould Brachytherapy Optimization

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All the patients were contoured, planned, and evaluated by a single evaluator to minimize interpersonal variations. All plans were optimized and calculated using Varian BrachyVision (version 13.0), which has both standard TG-43 formalism, and Acuros^® BV (version 1.4.0) developed by Transpire, Inc., Gig Harbor, Washington, USA, which was integrated into Eclipse treatment planning system (Varian Medical Systems Inc., Palo Alto CA, USA). Planned treatments were executed in GammaMedPlus^® iX (Varian Medical Systems Inc., Palo Alto CA, USA), with a maximum activity of 370 GBq ¹⁹²Ir stepping radioactive source to deliver the prescribed dose with decay correction. HDR brachytherapy plans were firstly performed using TG-43 formalism and inverse planning adaptive volume optimization. This was achieved with specific objectives for target volume and normal tissue sparing, followed by GBBS algorithm-based calculation (Acuros^® BV). During planning, surface mould brachytherapy with catheter flap calculation resolution was set to 1 mm as a standard to provide the best output. Similarly, the matrix grid was identically ensured in both the calculation methods. Both EBRT and HDR surface mould brachytherapy plans were evaluated at the same time in order to arrive at a conclusion on organ dose-limiting and to evaluate skin dose.

Sinnatamby M., Neelakandan V., Karunanidhi G., Kandasamy S., Ramapandian S., Kannan M, & Sampath E. (2021). Impact of GBBS algorithm on post-mastectomy scar boost irradiation of breast using catheter flap. Journal of Contemporary Brachytherapy, 13(3), 310-317.

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Phantom-Based 192-Ir Source Dosimetry

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The measurement itself is performed with the head phantom positioned on the treatment couch and the IP to the side of the head ( Fig. 2 a) or below the couch ( Fig. 2 b). The experiments were performed using a Gam-maMed Plus HDR 192-Ir source and GammaMed Plus iX afterloader (Varian Medical Systems). The used IP (PAXS-CAN 2530HE, Varex Imaging), has a detection area of 24.5 × 30.2 cm 2 , with 1792 by 2176 pixels and 0.139 mm resolution. As determined to be the optimal settings in previous research ( 13 ) (link), the 2 × 2 pixel binning mode was used. Binning was beneficial, because it allows for a higher frame rate (10 fps), requires less storage data, and the full image resolution is unnecessarily high for our purposes, for which 0.28 mm suffices. The intended position of the IP will be either on the lateral side of the patient, or below the treatment table (see Fig. 2 b). Due to the fact that the table will attenuate gamma rays coming from the 192 Ir source, its effect on the IP acquisitions had to be investigated. The distance of the surface of the phantom to the patient was set at 25 cm.

van Wagenberg T., Fonseca G.P., Voncken R., van Beveren C., van Limbergen E., Lutgens L., Vanneste B.G.L., Berbee M., Reniers B, & Verhaegen F. (2023). Treatment verification in high dose rate brachytherapy using a realistic 3D printed head phantom and an imaging panel. Brachytherapy, 22(2).

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